Protein
Zinc finger and BTB domain-containing protein 32
Function
DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity).
Similarity
Belongs to the krueppel C2H2-type zinc-finger protein family.
Sequence
MSLPPIRLPSPYGSDRLVQLAARLRPALCDTLITVGGQEFPAHSLVLAGVSQQLGRRGQWALGEGISPSTFAQLLNFVYGESVELQPRELRPLQEAARALGVQSLEEACWRARGDRAKKPDPGLKKHQEEPEKPSRNAERELGDPGEKQKPEQVSRTGGREQEMLHKHSPPRGSPEMAGATQEAQQEQTRSKEKHLQAPVGQRGADGKHGVLMWLRENPGGSEESLHKLPGPLPPAGSLQTSVTPRPSWAEAPWLVGGQPALWSILLMPPRYGIPFYHSTPTTGAWQEVWREHRIPLSLNAPKGLWSQNQLASSSPTPGSLPQGPAQLSPGEMEESDQGHTGALATCAGHEDKAGCPPRPHPPPAPPARSRPYACSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRXXLCGAGCPSLASMQAHMRGHSPSQLPPGWTIRSTFLYSSSRPSRPSTSPCCPSSSTT