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ZBTB18

Gene
zbtb18
Protein
Zinc finger and BTB domain-containing protein 18
Organism
Danio rerio
Length
537 amino acids
Function
Transcriptional repressor that plays a role in various developmental processes. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes (By similarity).
Similarity
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
Mass
59.193 kDa
Sequence
MEFPDHSRHLLQCLSEQRHQGFLCDSTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKSLPVEDVLAAASYLHMYDIVKVCKKKLKQKATAEADSTKREEDTSSCSDKVESFSEGGSTGRPATADLLQSDDEDMENKRDSPQEPGSMWMRLPSDRTTSPTTSPREAETHGPDAGKSPAGSPSSSSGSLSRRSAASRRVSADTDCVLDLSVKSSLGGGPGENIAGNPYFCSSVTPDSLQSALVQVKVEKDTGSDDDELVSGDYEMEHSGVKEPPSTNGTHLSLVAQRRLGLEAHLSALREASLASELERDDKGGDDDTDVLGGDSDRVQEAAGVESSLLPYVSSMLGAPHTQIFMCPLCNKVFPSPHILQIHLSTHFREQEGVRAKPAGDVNVPTCSICGKTFSCMYTLKRHERTHSGEKPYTCTTCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALNLPTVRDWALEDSSQELWK

Gene
ZBTB18
Protein
Zinc finger and BTB domain-containing protein 18
Organism
Homo sapiens
Length
522 amino acids
Function
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.
Similarity
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
Mass
58.354 kDa
Sequence
MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK

Gene
Zbtb18
Protein
Zinc finger and BTB domain-containing protein 18
Organism
Mus musculus
Length
522 amino acids
Function
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. May also play a role in the organization of chromosomes in the nucleus.
Similarity
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
Mass
58.385 kDa
Sequence
MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHMAGDLPSDEDEGEDDKLNILPSKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMENSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK

Gene
Zbtb18
Protein
Zinc finger and BTB domain-containing protein 18
Organism
Rattus norvegicus
Length
522 amino acids
Function
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. May also play a role in the organization of chromosomes in the nucleus (By similarity).
Similarity
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
Mass
58.31 kDa
Sequence
MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHMAGDLPSDEDEGEDDKLNILPSKRDLAAEPGNMWMRLPSDAAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRGNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSANNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWR

Gene
ZBTB18
Protein
Zinc finger and BTB domain-containing protein 18
Organism
Bos taurus
Length
522 amino acids
Function
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. May also play a role in the organization of chromosomes in the nucleus (By similarity).
Similarity
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
Mass
58.356 kDa
Sequence
MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHMAGDLPSDEDEGEDEKLNILPSKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELEREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGLRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPAVRDWTLEDSSQELWK

Gene
zbtb18
Protein
Zinc finger and BTB domain-containing protein 18
Organism
Xenopus tropicalis
Length
521 amino acids
Function
Transcriptional repressor that plays a role in various developmental processes. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes (By similarity).
Similarity
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
Mass
58.45 kDa
Sequence
MEFPEHSRHLLQCLSEQRHQGFLCDCTVLVGDAHFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKIECLSDGSSHMAGDLPSDEDDVEEEKINILPGKTDLATESGNMWIRLPSDSASIPQTGGEAETHTAAAGKTADSPCSSTGSLSHRSATSMRDSADVDCVLDLSVKSSLSGAETLNNSYLSSQEILRNSLVQVKVEKEASCDENDIDTTEYDIERNTVKESSSSNIRAPYEPVHLAPIREDSVLRELDHDDKASDDDITPENERVQMETNMDSSLLPYVPNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQEGIRSKPANDVHVPTCSLCGKTFSCMYTLKRHERTHSGEKPFTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSETLGLPAVRDWTLEDSSQELWK

Gene
zbtb18
Protein
Zinc finger and BTB domain-containing protein 18
Organism
Xenopus laevis
Length
520 amino acids
Function
Transcriptional repressor that plays a role in various developmental processes. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes (By similarity).
Similarity
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
Mass
58.57 kDa
Sequence
MEFPEHSRHLLQCLSEQRHQGFLCDCTVLVGDAHFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGILQFKGLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTDSTKKEEDTSSFSDKVECLSDGSSHMAGDLPSDEDDVEDEKINILPGKTDLATESRNMWIRLPTESASIPRTVGEAETHTTAAGKTAVSPCSSTGSLSHRSAISMGDSADVDCVLDLSVKSSLSGTETMNNSYLSSQEILRNSLVQVKVEKEATCDKNDIDTTEYDIERNTVKESVSSNIRASYEPVHLAPIREDSVLRELDHDDKASDDDMITLENERVQMEANTDNSLLPYVPNIISPTGQIFMCPLCNKVFPSPHILQIHLSTHFREQEGIRSKPANDVHVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSETLGLPAVRDWTLEDSSQELWK