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YFH1

Gene
YFH1
Protein
Frataxin homolog, mitochondrial
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
174 amino acids
Function
Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. Plays a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). Can store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization. May be involved in regulation of the mitochondrial electron transport chain.
Similarity
Belongs to the frataxin family.
Mass
19.49 kDa
Sequence
MIKRSLASLVRVSSVMGRRYMIAAAGGERARFCPAVTNKKNHTVNTFQKRFVESSTDGQVVPQEVLNLPLEKYHEEADDYLDHLLDSLEELSEAHPDCIPDVELSHGVMTLEIPAFGTYVINKQPPNKQIWLASPLSGPNRFDLLNGEWVSLRNGTKLTDILTEEVEKAISKSQ

Gene
YFH1
Protein
Frataxin, mitosomal
Organism
Encephalitozoon cuniculi (strain GB-M1)
Length
118 amino acids
Function
Promotes the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways.
Similarity
Belongs to the frataxin family.
Mass
13.906 kDa
Sequence
MLHKQTPEDVITRQLYHKLADETLTDLSEQLDKELDGGYADYKDGNLQIKIDNVGEYMFNKQPASMQIWASSPITGPRKFDICRRHEWIDLKSNTSFSRYIEEELRRMRSKMAGKHKK

Gene
YFH1
Protein
Frataxin
Organism
Trachipleistophora hominis
Length
107 amino acids
Function
Promotes the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways.
Similarity
Belongs to the frataxin family.
Mass
12.434 kDa
Sequence
MLQKIADQRSYLTAAHNTLTALEKKLDNDYGEIEHNNNVIEYTVDGVGRYVVSRQPSVMELWVSSPITGPSKFGMVEKKFVEKKNGMEIMKYFEMEMERIKRMLGNR