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XYLT2

Gene
XYLT2
Protein
Xylosyltransferase 2
Organism
Bos taurus
Length
867 amino acids
Function
Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN (By similarity). Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein (By similarity).
Similarity
Belongs to the glycosyltransferase 14 family. XylT subfamily.
Mass
97.189 kDa
Sequence
MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSVLEDDEPGEKGRQKKSRPLDPSEGSKDTDSSAGRRGSAGRRHGRWRGRAESPGVPVAKVVRAVTSRHRTGRRIPPTPPPEAPGRQNLSGAAAEEALVGAAGFPHGDTGSVEGAPQPTDNSFTPKCEIVGKDALSALARASSKQCQQEIANVVCLHQAGSLMPKAVPRHCQRAGKMSPGIPWDEVRAQQPADGPPVRIAYMLVVHGRAIRQLKRLLKAVYHKQHFFYVHVDERSNYLHREVVELARQYDNVRVTPWRMVTIWGGASLLRMYLRSMQDLLEVPGWAWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDNSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYTDDPLVAQLRQFYTYTLLPAESFFHTVLEISPACESLVDNNMRVTTWNRKMGSKSQYKHIVDWCGCSPNDFKPQDFLRLQQTARPTFFARKFEAVVNQEIIGQLDYYLYGNYPAGTPGLRSYWENVYDEPDGIHSLSDVTLTLYHSFSRLGLRRAEASLRAPGESSCRFEPRGLPSSVHLYFYDDHFQGYLVTQAVQSSAQGPAETLEMWLMPQGSLKLLGHSDQASRLQSLEVGQVGTEWDPKERLFRNFGGLLGPLDEPVAMQRWARGPNLTVTVVWIDPTYVVATSYDIVVDAETEVTQYKPPLSRPLRPGAWTVRLLQFWEPLGETRFLVLPLTFNRKLPLRKGKFSQMIAGPPHNEYMEQSFQGLSGILNLPQLEPAEEAARLHAELTGPALEAWTDGEQSSFWSVAGVCAVGPSACPSLELCRLTSWSSLSPDPKSELGPVKADGRLR
Protein
Xylosyltransferase 2: XYLT2

Gene
XYLT2
Protein
Xylosyltransferase 2
Organism
Canis lupus familiaris
Length
865 amino acids
Function
Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN (By similarity). Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein (By similarity).
Similarity
Belongs to the glycosyltransferase 14 family. XylT subfamily.
Mass
96.741 kDa
Sequence
MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSGLEEDEPGEKGRQRKPRPLDPGEGSKDTDSSAGRRGSAGRRHGRWRGRAESPGMPVAKVVRAVTSRHRASRRVPPAPPPEAPGRQNLSGAAAGEALVGAAGFPPHGDTGSVEGAPQPTDNGFTPKCEIVGKDALSALARASSKQCQQEIANVVCLHQAGNLMPKAVPRHCQLAGKMNPGIQWDEVRAQQPVDGPPVRIAYMLVVHGRAIRQLKRLLKAVYHEQHFFYIHVDKRSNYLHREVVELARQYDNVRVTPWRMVTIWGGASLLRMYLRSMQDLLEVPGWAWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDNSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYTDDPLVAQLRQFYTYTLLPAESFFHTVLENSPACESLVDNNLRVTNWNRRLGCKCQYKHIVDWCGCSPNDFKPQDFLRLQQVSRPTFFARKFESTVNQEVLEILDFHLYGSYPPGTPALKAYWENTYDAADGPGGLSDVMLTAYTAFARLSLRHAATAIPPLATPLCRFEPRGLPSSVHLYFYDDHFQGYLVTQAVQPSAQGPAETLEMWLMPQGSLKLLGRSDQASRLQSLEVGTEWDPKERLFRNFGGLLGPLDEPVAMQRWARGPNLTATVVWIDPTYVVATSYDIAVDADTEVTQYKPPLSRPLRPGAWTVRLLQFWEPLGETRFLVLPLTFNRKLPLRKDDASWLHAGPPHNEYMEQSFQGLSGILNLPQPEPAEEAARRHAELTGPALEAWTDGELSGFWSVAGLCAMGPSACPSLELCRLTSWSSVFPDPKSELGPVKADGRLR
Protein
Xylosyltransferase 2: XYLT2

Gene
XYLT2
Protein
Xylosyltransferase 2
Organism
Homo sapiens
Length
865 amino acids
Function
Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein.
Similarity
Belongs to the glycosyltransferase 14 family. XylT subfamily.
Mass
96.767 kDa
Sequence
MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSGLEEDEAGEKGRQRKPRPLDPGEGSKDTDSSAGRRGSTGRRHGRWRGRAESPGVPVAKVVRAVTSRQRASRRVPPAPPPEAPGRQNLSGAAAGEALVGAAGFPPHGDTGSVEGAPQPTDNGFTPKCEIVGKDALSALARASTKQCQQEIANVVCLHQAGSLMPKAVPRHCQLTGKMSPGIQWDESQAQQPMDGPPVRIAYMLVVHGRAIRQLKRLLKAVYHEQHFFYIHVDKRSDYLHREVVELAQGYDNVRVTPWRMVTIWGGASLLRMYLRSMRDLLEVPGWAWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDNSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYTDDPLVAQLRQFYTYTLLPAESFFHTVLENSLACETLVDNNLRVTNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFLRLQQVSRPTFFARKFESTVNQEVLEILDFHLYGSYPPGTPALKAYWENTYDAADGPSGLSDVMLTAYTAFARLSLHHAATAAPPMGTPLCRFEPRGLPSSVHLYFYDDHFQGYLVTQAVQPSAQGPAETLEMWLMPQGSLKLLGRSDQASRLQSLEVGTDWDPKERLFRNFGGLLGPLDEPVAVQRWARGPNLTATVVWIDPTYVVATSYDITVDTETEVTQYKPPLSRPLRPGPWTVRLLQFWEPLGETRFLVLPLTFNRKLPLRKDDASWLHAGPPHNEYMEQSFQGLSSILNLPQPELAEEAAQRHTQLTGPALEAWTDRELSSFWSVAGLCAIGPSPCPSLEPCRLTSWSSLSPDPKSELGPVKADGRLR
Protein
Xylosyltransferase 2: XYLT2

Gene
Xylt2
Protein
Xylosyltransferase 2
Organism
Mus musculus
Length
865 amino acids
Function
Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN (PubMed:17517600). Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein (By similarity).
Similarity
Belongs to the glycosyltransferase 14 family. XylT subfamily.
Mass
96.811 kDa
Sequence
MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSGLEEDEPGEKGRQRKPRPLDPGEGSKDTDSSAGRRGSAGRRHGRWRGRAESPGVPVAKVVRAVTSRQRASRRVPPAPPPEAPGRQNLSGAAAGEALIGAPGFPQHGDTGSVEGAPQPTDNTFTPKCEIVGKDALSALARASTKQCQQEIANVVCLHQAGNLMPKSVPRHCQLAGKMSPGVQWEEIRAQQPVGGPPVRIAYMLVVHGRAIRQLKRLLKAVYHEQHFFYIHVDKRSNYLYREVVELAQHYENVRVTPWRMVTIWGGASLLRMYLRSMKDLLEIPGWTWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDNSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYTDDPLVAQLRQFYTYTLLPAESFFHTVLENSPACASLVDNNLRVTNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFLRLQQVSRPTFFARKFESTVNQEVLEILDFHLYGSYPPSTPALKAYWENIYDVADGPGGLSDVLLTAYTAFARLSLRHAATAVSPLATAVCRFEPRGLPSSVHLYFYDDHFQGYLVTQAVQPSAQGPAETLEMWLMPQRSLKLLGHSDQASRLQSLEVGTEWDPKERLFRNFGGLLGPLDEPVAMQRWARGPNLTATVVWIDPTYVVATSYDITVDADTEVTQYKPPLSLPLRPGAWTVRLLQFWEPLGETRFLVLPLTFNRKLPLRKDDASWLHAGPPHNEYMEQSFQGLSGILNLPQAEALEEAARRHTELTGSALEAWTDGELSNFWSVAGLCAIGPSACPSLELCRLTSWSSLSPDPKSELGPVKADGRLR
Protein
Xylosyltransferase 2: Xylt2

Gene
XYLT2
Protein
Xylosyltransferase 2
Organism
Pan troglodytes
Length
865 amino acids
Function
Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN (By similarity). Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein (By similarity).
Similarity
Belongs to the glycosyltransferase 14 family. XylT subfamily.
Mass
96.713 kDa
Sequence
MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSGLEEDEAGEKGRQRKPRPLDPGEGSKDTDSSAGRRGSTGRRHGRWRGRAESPGVPVAKVVRAVTSRQRASRRVPPAPPPEAPGRQNLSGAAAGEALVGAAGFPPHGDTGSVEGAPQPTDNGFTPKCEIVGKDALSALARASTKQCQQEIANVVCLHQAGSLMPKAVPRHCQLTGKMSPGIQWDESQAQQPMDGPPVRIAYMLVVHGRAIRQLKRLLKAVYHEQHFFYIHVDKRSNYLHREVVELAQGYDNVRVTPWRMVTIWGGASLLTMYLRSMRDLLEVPGWAWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDNSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYTDDPLVAQLRQFYTYTLLPAESFFHTVLENSLACETLVDNNLRVTNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFLRLQQVSRPTFFARKFESTVNQEVLEILDFHLYGSYPPGTPALKAYWENTYDAADGPSGLSDVMLTAYTAFARLSLHHAATAAPPMGTPLCRFEPRGLPSSVHLYFYDDHFQGYLVTQAAQPSAQGPAEMLEMWLMPQGSLKLLGRSDQASRLQSLEVGTDWDPKERLFRNFGGLLGPLDEPVAVQRWARGPNLTATVVWIDPTYVVATSYDITVDTETEVTQYKPPLSRPLRPGPWTVRLLQFWEPLGETRFLVLPLTFNRKLPLRKDDASWLHAGPPHNEYMEQSFQGLSSILNLPQPELAEEAAQRHTQLTGPALEAWTDRELSSFWSVAGLCAIGPSPCPSLEPCRLTSWSSLSPDPKSELGPVKADGRLR
Protein
Xylosyltransferase 2: XYLT2

Gene
Xylt2
Protein
Xylosyltransferase 2
Organism
Rattus norvegicus
Length
864 amino acids
Function
Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN (By similarity). Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein (By similarity).
Similarity
Belongs to the glycosyltransferase 14 family. XylT subfamily.
Mass
96.79 kDa
Sequence
MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSGLEEDEPGEKGRQRKPRPLDPGEGSKDTDSSAGRRGSAGRRHGRWRGRAESPGVPVAKVVRAVTSRQRASRRVPPAPPPEAPGRQNLSGAAAGEALIGAAGFPQHGDTGSVEGAPQPTDNSFTPKCEIVGKDALSALARASTKHCQQEIANVVCLHQAGNLMPKSVPRHCQLAGKVSPGIQWEEVRAQQPVSGPLVRIAYMLVVHGRAVRQLKRLLKAVYHEEHFFYIHVDKRSNYLYREVVELAQHYDNVRVTPWRMVTIWGGASLLRMYLRSMKDLLETPGWTWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDNSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYTEDPLVAQLRQFYTYTLLPAESFFHTVLENSPACESLVDNNLRVTNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFLRLQQVSRPTFFARKFESTVNQEVLEILDFHLYGSYPPGTPALKAYWENIYDMADGPSGLSDVLLTAYTAFARISLRHAATVSPLATAVCRFEPRGLPSSVHLYFYDDHFQGYLVTQAVQPSAQGPAETLEMWLMPQRLLKPLGHSDQASRLQSLEVGTEWDPKERLFRNFGGLLGPLDEPVAMQRWARGPNLTATVVWIDPTYVVATSYDITVDADTEVTQYKPPLSLPLRPGAWTVRLLQFWEPLGETRFLVLPLTFNHKLPLRKDDASWLHAGPPHNEYMEQSFQGLSGILNLPQPEAVEEAARRHTELTGPALEAWTDGELSSFWSVAGLCAIGPSSCPSLELCRLTSWSSLSPDPKSELGPVKADGRLR
Protein
Xylosyltransferase 2: Xylt2