Function
Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Contributes to the trafficking of Golgi stacks, mitochondria and peroxisomes. Required for development of pavement cells, trichomes, and stigmatic papillae.
Sequence
MAAPVIIVGSHVWVEDPHLAWIDGEVTRIDGINVHVKTKKGKTVVTNVYFPKDTEAPSGGVDDMTKLSYLHEPGVLRNLETRYELNEIYTYTGNILIAVNPFQRLPHIYETDMMEQYKGIALGELSPHVFAIGDAAYRAMINEGKNNSILVSGESGAGKTETTKMLMRYLAFLGGRSGVEGRTVEQQVLESNPVLEAFGNAKTLRNNNSSRFGKFVEIQFDKNGRISGAAIRTYLLERSRVCQISDPERNYHCFYLLCAAPPEDIKKYKLENPHKFHYLNQSSCYKLDGVDDASEYLETRRAMDVVGISNEEQEAIFRVVAAILHLGNIDFGKGEEIDSSVIKDKDSRSHLNMAAELLMCNAQSLEDALIRRVMVTPEEIITRTLDPDNAIASRDTLAKTIYSHLFDWIVNKINTSIGQDPRSKSIIGVLDIYGFESFKCNSFEQFCINFTNEKLQQHFNQHVFKMEQEEYTKEEIAWSYIEFIDNQDVLELIEKKPGGIISLLDEACMFPKSTHETFSQKLFQTFKEHERFAKPKLSRTDFTISHYAGEVTYQSNHFIDKNKDYIVAEHQALFTASNCKFVAGLFHALHEDSSRSSKFSSIGSRFKQQLHSLMESLNGTEPHYIRCIKPNNVLKPGIFENFNVIHQLRCGGVLEAIRISCAGYPTRLAFYDFLDRFGLLAPEVLEGNYDDKVACQMILDKKSLTDYQIGKTKIFLRAGQMAELDARRAEVLGNAARVIQRQFRTCMARKNYRSIRNAAIVLQSFLRGEIARAVHKKLRIEAAALRVQKNFRRYVDRKSFVTTRSSTIVLQTGLRAMIARSEFRLRRQRKAAIVLQAHWRGRQAFSYYTRLQKAAIVTQCAWRCRLARRELRMLKMAARDTGALKDAKNKLEQRVEELSLRLHLEKRLRTDLEEAKVQEVAKLQEALHTMRLQLKETTAMVVKEQEAARVAIEEASSVNKEPVVVEDTEKIDSLSNEIDRLKGLLSSETHKADEAQHAYQSALVQNEELCKKLEEAGRKIDQLQDSVQRFQEKVFSLESENKVLRQQTLTISPTTRALALRPKTTIIQRTPEKDTFSNGETTQLQEPETEDRPQKSLNQKQQENQELLLKSISEDIGFSEGKPVAACLIYKCLIHWRSFEVERTSIFNRIIETIASAIEMQENSDVLCYWLSNSATLLMFLQRTLKAGATGSITTPRRRGMPSSLFGRVSQSFRGSPQSAGFPFMTGRAIGGGLDELRQVEAKYPALLFKQQLTAFLEKIYGMIRDKMKKEISPLLASCIQVPRTPRSGLVKGRSQNTQNNVVAPKPMIAHWQNIVTCLNGHLRTMRANYVPSLLISKVFGQIFSFINVQLFNSLLLRRECCSFSNGEYVKTGLAELEKWCHDATEEFVGSAWDELKHIRQAVGFLVIHQKPKKSLKEITTELCPVLSIQQLYRISTMYWDDKYGTHSVSTEVIATMRAEVSDVSKSAISNSFLLDDDSSIPFSLDDISKSMQNVEVAEVDPPPLIRQNSNFMFLLERSD