Protein
Trans-prenyltransferase
Organism
African swine fever virus (isolate Warthog/Namibia/Wart80/1980)
Function
Trans-prenyltransferase that catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with different allylic diphosphates, such as dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), farnesyl diphosphate (FPP) and geranylgeranyl diphosphate (GGPP), farnesyl diphosphate being the best allylic substrate.
Similarity
Belongs to the FPP/GGPP synthase family. Asfivirus trans-prenyltransferase subfamily.
Sequence
MLHLIYISIIVVLIIILISYTRKPKYFRITAPRSVALFHGIHPLNPKNYKTFSEEFETILNNAIEDGDFKGQLTEPCSYALRGGKYIRPIILMEIVRACQLQHSFGAPIYPAEAALAVEYFHVASLIIDDMPSFDNDVKRRNKDTVWARFGVAKAQMSALALTMQGFQNICRQIDWIKEHCPRFPDPNQLGALLCTFVSHSLNSAGSGQLVDTPEKTIPFFKIAFIMGWVLGTGSVEDIGMIERAAHCFGNAFQLADDIKDHDTDTGWNYAKIHGKRKTFDDVAQFLQECKKILHGKKIYTSIWNEIFQKVINVALGT