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War-068

Gene
War-068
Protein
CD2 homolog
Organism
African swine fever virus (isolate Warthog/Namibia/Wart80/1980)
Length
381 amino acids
Function
May play an immunosuppressive role by inhibiting lymphocyte proliferation and subsequently facilitating viral replication and generalization of infection (By similarity). Responsible for viral hemadsorption, which may help viral spread. Increases virus replication in the tick vector at the step of virus uptake or replication in the tick gut. May play a role in the host Golgi reorganization to yield viral factories (By similarity).
Similarity
Belongs to the asfivirus CD2 homolog protein family.
Mass
43.624 kDa
Sequence
MIIKLIFLICFKIVLSINYWVRYNDTVTLNSNINSETEGIFWNFYNNTFNTIATCGKKNNVCECSNYDKSLYNITNNCSLTIFPNNTKIFNTTYQLVYSRNRINYTINLLLPVTSPIITYNCTQSLITCEKTNGTNIHLFLNLNDTINEYTNKSFLNYYWNSSELNNIFLATCIINNTLNSANTTKVINCTNPLLKSYQNYFLENIHTLFYMIIFIVSGITISIFISIITFLSLRKRKKHVEEIESPPPESNEEEQCQHDDTTSIHEPSPREPLLPKPYSRYQYNTPIYYMRPSTQPLNPFPLPKPCPPPKPCPPPKPCPPPKPCPPPKPCPPPKPCPPPKPCPPPESYSPPKPLPSIPLLPNIPPLSTQNISLIHVDRII