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War-045

Gene
War-045
Protein
Viral histone-like protein
Organism
African swine fever virus (isolate Warthog/Namibia/Wart80/1980)
Length
104 amino acids
Function
DNA-binding protein that plays a critical role in viral DNA replication and gene expression. Binds to both ssDNA and dsDNA with a binding site covering about 15 nucleotides. Displays DNA-supercoiling activity only when associated with the viral DNA topoisomerase 2.
Similarity
Belongs to the bacterial histone-like protein family.
Mass
11.579 kDa
Sequence
MSAKKKPTITKQELYSLVAADTQLNKALIERIFTSQQKIIQNALKHNQEVIIPPGIKFTVVTVKAKPARQGHNPATGEPIQIKAKPEHKAVKIRALKPVHDMLN