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WIPF2

Gene
WIPF2
Protein
WAS/WASL-interacting protein family member 2
Organism
Homo sapiens
Length
440 amino acids
Function
Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system.
Similarity
Belongs to the verprolin family.
Mass
46.289 kDa
Sequence
MPIPPPPPPPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNINDRSAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEYKHFQRIYPSKTNRAARGAPPLPPILR
Protein
WAS/WASL-interacting protein family member 2: WIPF2

Gene
Wipf2
Protein
WAS/WASL-interacting protein family member 2
Organism
Mus musculus
Length
440 amino acids
Function
Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system (By similarity).
Similarity
Belongs to the verprolin family.
Mass
46.297 kDa
Sequence
MPIPPPPPPPPGPPPPPTFNQANTEQPKLSRDEQRNRGALLQDICKGTKLKKVTNVNDRSAPVIEKPRGSSGGYGPGAAALQPKGGLFQGGVPKLRPVGAKDASEAPAGKPALQVPSSRAAAPRPPGSAASGRPHDDTDSNRASLPELPRMQRPSLPDLSRPNTASGTGMKHSSSAPPPPPPGRRANAPPTPLPLHSNKAQAYNREKPLPPTPGQRLHPGREGHPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSATPSLLSNRPPPPAREPPSRGAAPPPPPPMIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEYKHLQRVYPSKTNRAARGAPPLPPILR
Protein
WAS/WASL-interacting protein family member 2: Wipf2