WDR62

WD repeat-containing protein 62

1541 amino acids

Required for cerebral cortical development. Plays a role in neuronal proliferation and migration (By similarity). Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity).

168.899 kDa

MAALGTGGYVRNDAVEKLPTIMAGVPARRAQSSPPPAPPLCLRRRTRLTAAPEDAVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILNPKENKQQHILNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTVGNRHVRFWFLEVSTEAKVTGTVPLVGRSGILGELHDNVFCGVACGRGQMAGSTFCVSYSGLLCQFNEKRVLEKWINLKVSLSSCLCVSQELIFCGCTDGIVRIFQAHSLHYLANLPKPHYLGVDVAQGLEPSFLFHRKAEAVYPDTVALTFDPNHQWLSCVYKDHSIYIWDVKDINKVGKMWSELFHSSYVWNVEVYPEFEDQRACLPSGSFLTCSSDNTIRFWNLDSNPDSHWQKNIFSDTLLKVVYVESDIQHLQDMSHFPDRGSENGMAVDMKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVRVEAHDAEVLCLEYSKPETGLTLLASASRDRLIHVLNVEKNYSLEQTLDDHSSSITAVKFTGSRDIQMISCGADKSIYFRSAQQASDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECVAKMFGHSEIITGMKFTYDCRHLITVSGDSCVFIWHLGPEITNCMKQHLLEIDQREQPQQNTKDGKWSRDPRQETCTSMPSEISLSPGEQTEDELEEECEPEELLKTPSKESLDSDPRCLLTNGKLPLWAKRLLGDDDVADGSAFHAKRSYQPHGRWAERADQEPLKTILDARDLDCYFTPMKPESLEDSILDTVESQRLAGLLSQSESPQEDGCRHPSLTPPQRESSEVSELLCSLESEVTITGTDSKPCAEEGEGAPGDQQDDFYLRVPSITSKDLNPPEDSGESEADLECSFTAVHSPPRPDPDPPFDVAVPPAPGCPGATEELARPEVPGLSNGSLPQTPEQEKFLRHHFETLTDAPAEELFHGSLRDLKASEAKDDFFNPRLSISAQFLSRFQKPSRFTHTFPTRLPRHPMQSPEVKLTDLAGSQPRAEPLRAGTGYTSPGRTNVLSAGKAEEPLEAWSPLTSCLTGLAPCVSSSSVPPTDKTPPTPTALPTPGLAQGVHTPATSSYVEATAGSRAKMSRSISLEDSKGPVLAELARPPCRPSSLGELSSLGQELRAITTTVTPSSDSEGQEPALPSRGNHEARASLKLTLSSICDRLLLPPPQLEPSAMCVWSQEPVAIQPNVMVTTASFSAPSPVNVSASRLHNSTFLPRFLAPEPLNTSAHPNSPPLPEARPGVPGNITSLLESAPDALSPVHRCPGHCGQPRVPARVPPPGPLELSNVGSIVHRLQTAFQEALDLYHMMVSRDEVSAEQQQAQTELASTFLWIHSQLEANDWLVGTDGAPAQALPSPGPPSPPTLCPLASPDLHALLEHYSELLVQAVRRKAQRD

Wdr62

WD repeat-containing protein 62

1523 amino acids

Required for cerebral cortical development. Plays a role in neuronal proliferation and migration (By similarity). Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity).

167.283 kDa

MAALAAGGYTRSDTIEKLSSVMAGVPARRNQSSPPPAPPLCLRRRTRLAAAPEDTVQNRVTLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVVLNPKENKQQHIFNTTRKSLSALAFSPDGKYIVTGENGHRPTVRIWDVEEKTQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTVGNRHVRFWFLEASTEAKVTSTVPLVGRSGILGELHNNIFCGVACGRGRMAGNTFCVSYSGLLCQFNEKRVLDKWINLKVSLSSCLCVSDELIFCGCTDGIVRIFQAHSLLYLTNLPKPHYLGVDVAHGLDSSFLFHRKAEAVYPDTVALTFDPVHQWLSCVYKDHSIYIWDVKDIDEVSKIWSELFHSSFVWNVEVYPEFEDQRACLPSGTFLTCSSDNTIRFWNLDSASDTRWQKNIFSDSLLKVVYVENDIQHLQDLSHFPDRGSENGTPMDMKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELIKVEAHDAEVLCLEYSKPETGVTLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGTRDVQMISCGADKSIYFRSAQQASDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVSGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISLIDFYSGECVAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWHLGPEITTCMKQHLLEINHQEQQQQPKDQKWSGPPSQETYASTPSEIRSLSPGEQTEDEMEEECEPEELLKTPSKDSLDPDPRCLLTNGKLPLWAKRLLGDDDVADSSAFHAKRSYQPHGRWAERAEQEPLKTILDAWSLDSYFTPMKPENLQDSVLDSVEPQNLAGLLSECSLGNGHTSPGEGLVSYLLHPELGSPKEDNRGHPSYLPLQREATEASELILCSPEAEVSLTGMHREYYEEETEAGPEDQQGDTYLRVSSVSSKDQSPPEDSGESEAELECSFAAAHSSAPQTDPGPHLTMTAGKPEYPSTEELSQPELPGLGNGSLPQTPEQEKFLRHHFETLTDAPTEELFHGSLGDIKISETEDYFFNPRLSISTQFLSRLQKTSRCPPRLPLHLMKSPEAQPVGQGGNQPKAGPLRAGTGYMSSDGTNVLSGQKAEETQEALSLLDRKPPTPTSVLTTGREQSISAPSSCSYLESTTSSHAKTTRSISLGDSEGPVTAELPQSLHKPLSPGQELQAIPTTVALTSSIKDHEPAPLSWGNHEARASLKLTLSSVCEQLLSPPPQEPPITHVWSQEPVDVPPSMAVTVASFCAPSPVDMSTLGLHSSMFLPKTSASGPLTPPAHLQLLETRSRVPGSTAALLEPTPDASGVIADSPGHWDTEVPTPELLGSVESVLHRLQTAFQEALDLYRMLVSSSQLGPEQQQAQTELASTFHWILNQLEASNCMAAANLAPPQTLPSPDPLSLPTLCPLASPNLQALLEHYSELLVQAVRRKARGD

WDR62

WD repeat-containing protein 62

1518 amino acids

Required for cerebral cortical development. Plays a role in neuronal proliferation and migration (PubMed:20890278, PubMed:20729831). Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (PubMed:26297806).

165.954 kDa

MAAVGSGGYARNDAGEKLPSVMAGVPARRGQSSPPPAPPICLRRRTRLSTASEETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTVGNRHVRFWFLEVSTETKVTSTVPLVGRSGILGELHNNIFCGVACGRGRMAGSTFCVSYSGLLCQFNEKRVLEKWINLKVSLSSCLCVSQELIFCGCTDGIVRIFQAHSLHYLANLPKPHYLGVDVAQGLEPSFLFHRKAEAVYPDTVALTFDPIHQWLSCVYKDHSIYIWDVKDINRVGKVWSELFHSSYVWNVEVYPEFEDQRACLPSGSFLTCSSDNTIRFWNLDSSPDSHWQKNIFSNTLLKVVYVENDIQHLQDMSHFPDRGSENGTPMDVKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIWHLGPEITNCMKQHLLEIDHRQQQQHTNDKKRSGHPRQDTYVSTPSEIHSLSPGEQTEDDLEEECEPEEMLKTPSKDSLDPDPRCLLTNGKLPLWAKRLLGDDDVADGLAFHAKRSYQPHGRWAERAGQEPLKTILDAQDLDCYFTPMKPESLENSILDSLEPQSLASLLSESESPQEAGRGHPSFLPQQKESSEASELILYSLEAEVTVTGTDSQYCRKEVEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDPAPRFATSLPHFPGCAGPTEDELSLPEGPSVPSSSLPQTPEQEKFLRHHFETLTESPCRALGDVEASEAEDHFFNPRLSISTQFLSSLQKASRFTHTFPPRATQCLVKSPEVKLMDRGGSQPRAGTGYASPDRTHVLAAGKAEETLEAWRPPPPCLTSLASCVPASSVLPTDRNLPTPTSAPTPGLAQGVHAPSTCSYMEATASSRARISRSISLGDSEGPIVATLAQPLRRPSSVGELASLGQELQAITTATTPSLDSEGQEPALRSWGNHEARANLRLTLSSACDGLLQPPVDTQPGVTVPAVSFPAPSPVEESALRLHGSAFRPSLPAPESPGLPAHPSNPQLPEARPGIPGGTASLLEPTSGALGLLQGSPARWSEPWVPVEALPPSPLELSRVGNILHRLQTTFQEALDLYRVLVSSGQVDTGQQQARTELVSTFLWIHSQLEAECLVGTSVAPAQALPSPGPPSPPTLYPLASPDLQALLEHYSELLVQAVRRKARGH