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WAR1

Gene
WAR1
Protein
Transcriptional regulator WAR1
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
947 amino acids
Function
Transcription factor required for yeast cell adherence to silicone substrate. Plays a role in resistance to weak organic acids such as acetate and sorbate. Binds in vitro to a nitric oxide-responsive element (NORE) but seems not to be involved in response to nitrosative stress.
Mass
105.854 kDa
Sequence
MSDTTPEKGSVDSVSPSASNGSNTNNPLNNSSPQPLKSNESDKKPKVTRRSVACKSCHSLKVKCTPSDPNNPSAPCVRCINANRICEIDLNQTRKRRKKSEILEAKRQAGQSLPEHKKEKNTPTQSGYNSSENYSSSINNANDSSLTSRYQSPMTFDPTSPMVFRPQASSAVPPISSNLNPQSAAPTPIPTSGIPPQLPSPHESAILRGNTTSPTSKDDEINQLKQRVRFLETELANKRLLANKKGFSNDSPTDLQSPPFVSKFDLESEISILAESSARLTDLTNQLNEAASRRIQLVSAKKPVDLISKGVITVAEAEERLKLYREQIYGRHPLIAIPDNMHAIEFSQSQPFLFNSIMSACNLITKNADKDVVLAIDNEAMTSVAVEVMVVGTKSVELVKAFSVLCLYYNSPELFKQRRYHMLNTICVSLLHDVGIFARPTYSYNQADGTLKQDASSKDKGNDEYRELVLITYFVTVSTCLVLRRSIYARWTPYVEECCSLLENSSQEKHRRLALFARMNNKLDKIHHIVHAPEMPGQKSGVSQYVIQELQRLLSDLKLKIKDNQYSLLSYYYSIEAYLHEPILTKVFKSDTELDGKAMKSIRYCTSSCLNALDEYSKLTPDQIALLPFPFGSRIMYTAGMLLRLRYLILSLPSHIDKELVPKRAVTSIQCVSKLVEQANILNPHNHYLTKMRLVLQLFIQTYATQVLELLSKNGNTPQNFKPDESETQQLRALAREYNDIRKVSKVSLVSDTRSAEPLDVLSYAATFRRENNDKPSAVAGSLRKSFSENDQAIKTPSQCGQFVSANNTPVPQVINSPPISQTNVPVLHQSQSIINGNNRNSAPLAFNNTTTPSLHQFGDVLPPSSMPQPDYRQFRLPSISNTVHYSSNPRLNANLANPDQLENSYQVLNDEFWSNLLSTDSTDRINFTSNNFNGNTSNDEVFFMNN

Gene
WAR1
Protein
Weak acid resistance protein 1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
944 amino acids
Function
transcription factor which binds to a weak acid response element (WARE) to mediate stress induction of PDR12 and FUN34, encoding an acid transporter and a putative ammonia transporter, respectively.
Mass
107.561 kDa
Sequence
MDTQIAITGVAVGKEINNDNSKTDQKVSLPKADVPCIDKATQTIIEGCSKDDPRLSYPTKLETTEKGKTKRNSFACVCCHSLKQKCEPSDVNDIYRKPCRRCLKHKKLCKFDLSKRTRKRKPRSRSPTPFESPMVNVSTKSKGPTDSEESSLKDGTSYLASFPSDPNAKQFPNSRTVLPGLQQSLSDLWSTLSQPPSYGAREAETTSTGEITTNNHTKSNGSVPTNPAVLASNDEHTNISDAPVIYSTYNSPVPISSAPTSINSEALFKHRPKIVGDEETQNVKVKRQKKSYSRHMTRSFRKQLQSLIISQKGKIRDISMKLDTWSKQWNDLVEKSMFLPTIADPVSVGIISHEEATLRLHLYKTEISYLSKLPFIKVEENVSVDELRKKKPILFSVIMSCVSIVLTPKQTTRGTIMKLDSFVLNLITNQIFKANNKSIEIIESLSTLCLWYNFFEWSSKTRYHIFNYICCCLTRDLGPTYVNRSFGMFSDEDPKRFKSPLELYSNGASLTLLVYISALNISIFLRQSIQARWSHVTEKACEDLVKETKKSRHYDNDKLLLDSADDPILVQFAKMNHVLENIHTHLHERDLNDDEFDDPIFTKKYLNKLMEKYHKQLQEIFTKLDRNRPRVIAFYYSVEAYLYQYKLAVFIGEMSHTINEKVELPREIMDDFVKCYHCCKSALEEFSKLEPILITSLPLFHTSRIIYTVGMLLLKLRYSVVAIPSFHDLMPLTDDAIALVIGVNNLLEKTSELYPFNNSLYKFRYVIALFCQTYANKVIDVADRYNAEREKLKEKQVIDEVSNGHDGTKPINAYVTESQKMPTEEDPIIDNNTNQNITAVPDEMLPVYSRVRDDTAAMNLNINSTSYMNESPHEHRESMTGTTLLPPPFISNDVTNSADSTNIKPSPSSSVDNLNDYLTDINSLAWGVNSLNDEFWTDLFMNDI