Protein
Thermolabile hemolysin
Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Function
Phospholipase hydrolyzing both fatty acid esters of phospholipid, i.e. it hydrolyzes phosphatidylcholine (PC) to lysophosphatidylcholine (LPC) and then LPC to glycerophosphorylcholine (GPC).
Similarity
Belongs to the 'GDSL' lipolytic enzyme family.
Sequence
MMKKTITLLTALLPLASAVAEEPTLSPEMVSASEVISTQENQTYTYVRCWYRTSYSKDDPATDWEWAKNEDGSYFTIDGYWWSSVSFKNMFYTNTSQNVIRQRCEATLDLANENADITFFAADNRFSYNHTIWSNDAAMQPDQINKVVALGDSLSDTGNIFNASQWRFPNPNSWFLGHFSNGFVWTEYIAKAKNLPLYNWAVGGAAGENQYIALTGVGEQVSSYLTYAKLAKNYKPANTLFTLEFGLNDFMNYNRGVPEVKADYAEALIRLTDAGAKNFMLMTLPDATKAPQFKYSTQEEIDKIRAKVLEMNEFIKAQAMYYKAQGYNITLFDTHALFETLTSAPEEHGFVNASDPCLDINRSSSVDYMYTHALRSECAASGAEKFVFWDVTHPTTATHRYVAEKMLESSNNLAEYRF