Organism
Arabidopsis thaliana
Function
Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). Involved in endocytosis via its action in endosomal trafficking.
Similarity
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class VIII subfamily.
Sequence
MMLSASPNTLAKSSLEEMLESLRQKDECDRPKDMPPALPSRPNSRARLPSARRSLPANFNVSSVMEDQNGSVVSVTPAVEAESERKEEGVKRKEKDLGVKRNSFGSKKMRTGLRSESPYAAEKEEEGVKISIAKVSLVENTEEHNKPESEWNNNVEYFIKKKLRVWCRVSNGQWQLGKIQSTSADTSLVMLSTANVVKVSTEELFPANPDILEGVEDLIQLSYLNEPSVLYNLRVRYLQDVIYSKAGPVLIAVNPFKNVEIYGNDVISAYQKKVMDAPHVYAVADAAYDEMMREEKNQSLIISGESGAGKTETAKFAMQYLAALGGGSCGVEYEILKTTCILEAFGNAKTSRNANSSRFGKLIEIHFSAMGKICGAKLETFLLEKSRVVQLFNGERSYHIFYELCAGASPILKERLKLKTASEYTYLSQSDCLTIAGVDDAQKFHKLLEAFDIVQIPKEHQERAFALLAAVLWLGNVSFRVTDNENHVEVVADEAVANAAMLMGCNTEELMVVLSTRKLQAGTDCIAKKLTLRQATDMRDGIAKFIYANLFDWLVEQINIALEVGKSRTGRSISILDIYGFESFKNNSFEQFCINYANERLQQHFNRHLFKLEQEEYEEDGIDWTKVEFVDNQECLDLIEKKPIGLLSLLDEESNFPKATDLTFANKLKQHLKTNSCFKGERGRAFRVNHYAGEVLYDTNGFLEKNRDPLPADLINLLSSCDCQLLKLFSTKMRGKSQKPLMLSDSTNQTVGTKFKGQLFKLMNKLENTSPHFIRCIKPNSKQLPRVYEEDLVLQQLRCCGVLEVVRISRSGYPTRLTHQEFAGRYGFLLSDKKVAQDPLSVSIAVLKQYDVHPEMYQVGYTKLYLRTGQIGIFEDRRKKVLQGIVGLQKHFRGHLSRAYFQNMRKVTLVLQSYIRGENARRLFDTEAKFHADSVSEASTDELSAVIHLQSAVRGWLARKHFNSMQRQKELRNVATKSKRKAGRRISEDKDIPLEQPQVQPTSMSDLQKRILKSEAALSQKEEENTALREQLRQFEERWSEYDIKMKSMEETWQKQMSSLQMSLAAARKSLAAESITGQAGGRQDTSISPFGYDSEDTMSTGTPGVRTPTNKFTNGNTPELRIRELNGSLNAVNHLAREFDQRRLNFDEDARAIVEVKLGPQATPNGQQQQHPEDEFRRLKLRFETWKKDYKARLRDTKARLHRVDGDKGRHRKWWGKRG