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VH1

Gene
VH1
Protein
Probable dual specificity protein phosphatase H1 homolog
Organism
Raccoon poxvirus
Length
171 amino acids
Function
Serine/Tyrosine phosphatase which down-regulates cellular antiviral response by dephosphorylating activated STAT1 and blocking interferon (IFN)-stimulated innate immune responses.
Similarity
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Mass
19.741 kDa
Sequence
MDKKSLYKYLLLRSTGDIHRAKSPTMMTRVTNNVYLGNYKNAMEAPSSEVKFKYILNLTMDKYSFTNSNINIIHVPMVDDTSTDISIYFDDITAFLSKCDQRNEPVLVHCAAGVNRSGAMILAYLMSKNKESSPMLYFLYVYHSMRDLRGAFVENPSFKRQIIEKYVIDKN