About Products Protein Database Contact

VDAC4

Gene
VDAC4
Protein
Mitochondrial outer membrane protein porin 4
Organism
Oryza sativa subsp. japonica
Length
317 amino acids
Function
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity).
Similarity
Belongs to the eukaryotic mitochondrial porin (TC 1.B.8.1) family.
Mass
33.757 kDa
Sequence
MEAETECKVPGVYSETGIPVEDPAPGLNSDVSKKDAPPAVAAPGPGLYFEIGKKARDLLYKDFHTDQKFTLTTYTNNGVVITAASTMKDEAIFSEIQTKLKSNNVMLDVKATSDSQVLTTITTEDLGVSGLKQIVSLPFPYQTAGKAELQYLHDYAGISLGVGLTSKPLVNLSGVFGNKSVAVGADVAVDTSTGDFTKYDAGLTINNSDLAADLTLNNKGDSLTASYYHLVNKESGTAAGAELTHSFSTKENTLSFGMQHALDPLTTVKARYNNHGMVSALIQHEWRPKSFLTLSAEVDTKAIDKASKVGLSLVLKP

Gene
VDAC4
Protein
Mitochondrial outer membrane protein porin 4
Organism
Arabidopsis thaliana
Length
274 amino acids
Function
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity). Involved in plant growth and development at the vegetative and reproductive stages. Is important for leaf and pollen development and mitochondrial membrane potential steady state. May be involved in disease resistance.
Similarity
Belongs to the eukaryotic mitochondrial porin (TC 1.B.8.1) family.
Mass
29.505 kDa
Sequence
MGSSPAPFADIGKKAKDLLNKDYIFDHKFTLTMLSATGTEFVATGLKKDDFFFGDISTLYKGQNTIVDLKIDSHSSVSTKVTLKNLLPSAKAVISFKIPDHKSGKLDVQYVHPHATLNSSIGLNPTPLLDLSATIGSQNVCLGGEVSFDTASSSLTKYNAGIGFNNQGVSAALILEDKGESLRATYVHTVNPTTSFGAELIRRFSNYNNSFTVGSSHSVDQFTVVKTRFSNSGKAGMVVQREWRPKSHITFSAEYDSKAVTSSPKLGLALALKP