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VACWR167

Gene
VACWR167
Protein
Profilin
Organism
Vaccinia virus (strain Western Reserve)
Length
133 amino acids
Function
Participates in either intracellular transport of viral proteins or intercellular spread of the virus. Cellular profilins modulate actin filament dynamics (polymerization and depolymerization) via direct binding to actin through an actin-binding domain as well as by modulation of other actin-binding proteins (By similarity). In contrast to cellular homologs, the poxvirus profilins seem to bind actin only weakly.
Similarity
Belongs to the profilin family.
Mass
15.052 kDa
Sequence
MAEWHKIIEDISKNNKFEDAAIVDYKTTKNVLAAIPNRTFAKINPGEIIPLITNRNILKPLIGQKYCIVYTNSLMDENTYAMELLTGYAPVSPIVIARTHTALIFLMGKPTTSRRDVYRTCRDHATRVRATGN