Organism
Vaccinia virus (strain Western Reserve)
Function
Plays a role in the inhibition of host innate immune response. Within the host nucleus, inhibits activation of interferon-beta promoter by inhibiting IRF3 activation.
Similarity
Belongs to the poxviridae N2 protein family.
Sequence
MTSSAMDNNEPKVLEMVYDATILPEGSSMDPNIMDCINRHINMCIQRTYSSSIIAILDRFLMMNKDELNNTQCHIIKEFMTYEQMAIDHYGGYVNAILYQIRKRPNQHHTIDLFKRIKRTRYDTFKVDPVEFVKKVIGFVSILNKYKPVYSYVLYENVLYDEFKCFINYVETKYF