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USB1

Gene
usb1
Protein
U6 snRNA phosphodiesterase
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
364 amino acids
Function
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.
Similarity
Belongs to the 2H phosphoesterase superfamily. USB1 family.
Mass
39.92 kDa
Sequence
MKRPLVDYDSGSGSESECGSSSDGPKSSSTNIPPQLKKRRNGDIGTRAPPSAPASTPIAPLGRSSGTHTIPPKPAPKSTSSLPPISDRFNDLYASNTRTAVSDDPSLHQGRQRQVPHIPGNWPSHVYIDWDPSSGDRELLSSLVDKLQTRVAAAAQRYPDLEGVKISTALRDPELPVDKPLHISLSAPLTLTSKNKDAFLDDVTRALRSSGVSPFVVDFSGGVNWYRSEESTRSFLVLRVREVQNTGMTTADSSPNPRLTTLLQRCNKTAKEYGQPPLYDSQDMGYRFHVTIAWTHARPSESLKQLTDSIFDDCKTMYSENMSIRDKLCTGSSFRVETVKVKIGNHVTRFELPDKGLALPVKTT

Gene
USB1
Protein
U6 snRNA phosphodiesterase
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
290 amino acids
Function
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 3'phosphate. Could be involved in aerobic respiration.
Similarity
Belongs to the 2H phosphoesterase superfamily. USB1 family.
Mass
33.694 kDa
Sequence
MEFISADYSSSDGSDTESESSNKSEVQIEYTEKTCIQKADSTDLPAIPDSIILKYHIPPNLQKYEHQDMNMSRFWRSFTYFEWRPTPAIHRQLQKIICKYKETFMKQEYTNPYQLVDFDPLFISHLGAPKPLHVSLTRSLLFETEEQRHVFIQEMRNGLRNNEITPFKLQICSYPKLYISERANTLYLGLPVSECPNKAQISPFKTIIAEALQKSGISNYQDLIVSRQNLHVSIAIASNPSKATLKRYQQLNETMGALLLLNNDFAYKLEFLVNSIYCDENRHSIRIPFN

Gene
usb1
Protein
U6 snRNA phosphodiesterase
Organism
Danio rerio
Length
276 amino acids
Function
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.
Similarity
Belongs to the 2H phosphoesterase superfamily. USB1 family.
Mass
31.57 kDa
Sequence
MIVNYSSSSSEEESGSSSSPSGKRQKLDTETSEALDHGSAQRKVCKSSHLTPRLPLPESVKEMFRDSEELWTDKSEEHGGRLRSFQHERGNWATYVFFPYDPEEAFLEVLNKMMAAAEAHDIPLTVSEEFHLSLSKTVVLRHHWIQPFVQSIRTSLTHFQKFYCVAYKLKVYSNAEKTRTFLGMEVSTGTPHLLELSKIVDETMKEFNLSTFYEDPSFHISLAWCVGDQTERLKKACLLELQGLIDAHEDGPFHARLNCNELRCKTGNKVFVFPLQ

Gene
Usb1
Protein
U6 snRNA phosphodiesterase
Organism
Mus musculus
Length
267 amino acids
Function
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.
Similarity
Belongs to the 2H phosphoesterase superfamily. USB1 family.
Mass
30.25 kDa
Sequence
MSSAPLVGYSSSGSEDEAEAVAAGRSKPGTGFHRCGQNPVPSEKLPVPDSVLSMFPSTEEGPEDDSAKHGGRIRTFPHERGNWATHIYIPYEAKEDFRDLLDALLPRAQMFVPRLVLMEEFHVSLSQSVVLRHHWILPFVQVLKDRMASFQRFFFTANRVKIYTNQEKTRTFIGLEVSSGHAQFLDLVSEVDRAMKEFDLTTFYQDPSFHISLAWCVGDASLQLEGQCLQELQEIVDEFEDSEMLLRVLANQVRCKSGNKFFSMPLK

Gene
Usb1
Protein
U6 snRNA phosphodiesterase
Organism
Rattus norvegicus
Length
267 amino acids
Function
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.
Similarity
Belongs to the 2H phosphoesterase superfamily. USB1 family.
Mass
30.475 kDa
Sequence
MNAAPLVGYSSSGSEDEAEAVAAGRSKPGSGLHRCGQNPLPSQRFPVPDSVLNMFPSTEEGPEDDSARHGGRIRTFPHERGNWATHIYIPYEANEEFQDLLDVLLPRAQMFAPRLVQMEEFHLSLSQSVVLRHHWILPFVQVLKDRMASFQRFFFTANRVKIYTNQEKTRTFIGLEVSSGHAQFLDMVSEVDRVMKEFDLTTFYQDPSFHVSLAWCVGDARLQLEGQCQQELQEIVDEFEDSEMLLRVLAEQVRCKSGNKFFSMPLK

Gene
USB1
Protein
U6 snRNA phosphodiesterase
Organism
Bos taurus
Length
265 amino acids
Function
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.
Similarity
Belongs to the 2H phosphoesterase superfamily. USB1 family.
Mass
29.957 kDa
Sequence
MSAAPLVGYSSSGSEDEAEAGARVRPGAEGRSRGQSPLPGQRLPVPDSVLHMFPSTEEGPVDDSAKHGGRVRTFPHERGNWATHVYIPYEAREEFLDLLDALLCHAQTYVPRLVRMEAFHLSLSQSVVLRHHWILPFVQALKDRVASFHRFCFTTDQVKIYTNQEKTRTFVGLEVTSGHAHFLDLVAEVDRVMEEFDLSTFYQDPSFHISLAWCVGDARLQMEGPCLQELQGIVDEFEDSEMLLRAYAEQIRCKSGNKFFSMPLK

Gene
USB1
Protein
U6 snRNA phosphodiesterase
Organism
Homo sapiens
Length
265 amino acids
Function
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.
Similarity
Belongs to the 2H phosphoesterase superfamily. USB1 family.
Mass
30.268 kDa
Sequence
MSAAPLVGYSSSGSEDESEDGMRTRPGDGSHRRGQSPLPRQRFPVPDSVLNMFPGTEEGPEDDSTKHGGRVRTFPHERGNWATHVYVPYEAKEEFLDLLDVLLPHAQTYVPRLVRMKVFHLSLSQSVVLRHHWILPFVQALKARMTSFHRFFFTANQVKIYTNQEKTRTFIGLEVTSGHAQFLDLVSEVDRVMEEFNLTTFYQDPSFHLSLAWCVGDARLQLEGQCLQELQAIVDGFEDAEVLLRVHTEQVRCKSGNKFFSMPLK

Gene
usb1
Protein
U6 snRNA phosphodiesterase
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
265 amino acids
Function
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.
Similarity
Belongs to the 2H phosphoesterase superfamily. USB1 family.
Mass
31.6 kDa
Sequence
MSLVCYESSSSGEDDDETISDNPRMLKVPKLQESFHELYKKKPKTFDSPEFHEGRIRGQKHIEGLWFVQTYLEVDLSKKVKKGIREFLNSQSRFQSLLCSEHNVPRRLHLSISENYRINYSTKNQLVHKWEQYTNNLNYRTLKFRLGKMCLLFNDEKTRMFLAFECKFSDENYKDLISHASDCMKEFTNRNLREDFLLHISFASSLTNEDEYQNWVSQDRESHFFKTMNEIINTKIQKDQFSESFIVDSLKLSIGHLIFTFPFCK

Gene
usb1
Protein
U6 snRNA phosphodiesterase
Organism
Xenopus laevis
Length
250 amino acids
Function
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.
Similarity
Belongs to the 2H phosphoesterase superfamily. USB1 family.
Mass
28.999 kDa
Sequence
MALVSYSSSEEDEGETSEPPGRRLPPLPPPTTVLRMFQDMEGDEDLDENTKHEGRIRSFKHERGNWATYVYIPFQPQEEFLDLLDELVSVAAENGVLLTKMSEFHISQSQTVVLRHHWINPFVESLKDKLHCMYRFLCIAERIKVYTNQEKTRTFLGLEVSVGMEHLLEVVSEVDRSLQEFNLQTFYQEPSFHVSLAWCVGDKYEKLKGSCLLELQKVIDRFEDSDTLTRFNAEEIRCKAGNKTFCIPLL