URB2

Gene

URB2

Protein

Unhealthy ribosome biogenesis protein 2 homolog

Organism

Homo sapiens

Length

1524 amino acids

Mass

170.544 kDa

Sequence

MAAVYSGISLKLKSKTTSWEDKLKLAHFAWISHQCFLPNKEQVLLDWARQSLVAFYKKKLELKEDIVERLWIYIDNILHSRKLQNLLKNGKTINLQISLVKIINERVAEFSLSGSQRNICAVLRCCQGILSTPALAVIYTAKQELMVALLSQLCWSACRQPEGAVVAQLFEVIHLALGHYLLILQQQVNPRRAFGDVTAHLLQPCLVLRHLLSGGTWTQAGQGQLRQVLSRDIRSQIEAMFRGGIFQPELLSSYKEGLLDQQQGDVKTGAMKNLLAPMDTVLNRLVDAGYCAASLHTSVVANSVALLYKLFLDSYFKEGNQLLCFQVLPRLFGCLKISHLQEEQSKALSTSDWTTELLVVEQLLNSVANNNIYNIAADRIRHEEAQFRFYRHVAELLINHAQAPIPAWFRCLKTLISLNHLILEPDLDDLLASAWIDAEVTEFRTKKAQEALIRTVFQTYAKLRQVPRLFEEVLGVICRPAAEALRQPVLASGPSTVLSACLLELPPSQILDTWSLVLEKFQSLVLPYLQSDADMALKSLSLSLLLHCIMFNMRSLDSSTPLPIVRRTQCMMERMMRELVQPLLALLPDTPGPEPELWLQKVSDSVLLLSYTWAQVDAMFSLNCSQYHSMSGPLIGVALEISNLPSLLPGVKTQHWKKIEKFTAQFSSLGTYCLEQLYLQKMKRTLMQTSFRSEGAIQSLRCDAAFIIGSGRKSLNQRTTASWDGQVGMVSGLTYPVAHWHLIVSNLTILISYLCPDDVGYLASVLLRTLPMGKAQEVSIDEEAYITLEKISKAFLHSPLFPEMQSLHSAFLTCVTTSCSSILCSGAQRDSGLVSQQLPWLFEKDHMVVGHWENRFAKAGPEGIEPRGEIAQNLLSLVKSDFPIQLEGEQLESILGLLEVISALQLDSLLPPYHVHYFLVLLSMAVTKLGCSCSSSLALKFLTTCYQLLGYLQKGKSARSVFKIMYGSDIFEVVLTSLFRASSRFLIEMDDPAWLEFLQVIGTFLEELMQMLIQMKLSLVLNFRKITAFLSSSKPYTEAASSKQLENQNPQGRQLLLVSLTRLCHVLGPFLKEQKLGQEAPAALSELLQQVVLQTGAVLQLCSVPGARGWRLPSVLISSVSTLLEADLGQHCRDGGADISQGSDRTLLSHVALYQGVYSQILLELPALAGHDQSFQAALQFLTLFFLAPELHPKKDSVFTSMFHSVRRVLADPEIPVQVTQDIEPHLGALFTQMLEVGTTEDLRLVMQCILQGLDVSNMWKADVQAVVSAVTLLRLLLNCPLSGEKASLLWRACPQIVTALTLLNREASQEQPVSLTVVGPVLDVLAALLRQGEEAIGNPHHVSLAFSILLTVPLDHLKPLEYGSVFPRLHNVLFSILQCHPKVMLKAIPSFLNSFNRLVFSVMREGRQKDKGSIDDLPTVLKCARLVERMYSHIAARAEEFAVFSPFMVAQYVLEVQKVTLYPAVKSLLQEGIYLILDLCIEPDVQFLRASLQPGMRDIFKELYNDYLKYHKAKHEGEKRYTA

Protein

Unhealthy ribosome biogenesis protein 2 homolog: URB2

Gene

urb2

Protein

Probable nucleolar pre-ribosomal-associated protein 2

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

1318 amino acids

Function

Required for 27S pre-rRNA processing. Has an early role during 60S ribosomal subunit assembly (By similarity).

Mass

151.57 kDa

Sequence

MSLQTLTKRIRDKNGSREDQIDLANKLFRGEVDVYFPNKEEFIINFLLDRLKENSNLTCVNIGYWQLFLNIWKSDKLSGSFRVSAIRRQSLYPIILNAFEYLIKEFKKDVFLKISDVFVCVYSNLNILYISRSFPDQISLLFSRYCYLIASKIDDLLDSHPNEVFKETLICVIQSAVHSQASSTKAQTQFLHQTLGSILALLCKTQKGDPYFSFLNAVLMKCVLTQHTLDVLLLTKKDSSMTLCSLLNAISFEPINLKAIPLFFIICADSINFHLSSVEKSISQQKASELMYKLFSEHIAFLLSLKNLPEEATLDCMLSICQVFENDNLHRGHSDEYTFAMLEQLLELSVKTLRQNTCWSTSWEMLSSLLAIDFDVLLPHSKILWECIKSVSHQDDIHALKFLKRWVRASAKARILDSFCIDWHLNVQTMSERSILTNRDFITSFSAVAEVSLSQISIKKLVTWLMSSESIMSENSNRFVVYYSLCKSLKRESYPAHLVPNFELFTRSIFNASLKNFNILDERSQALLCMCQISHVQFFSSDMSISASVGMKTLFEDLMAEKSRGLSSTVWSLQLLLCYLEQCLRLNTLHEDTTFPMRVVNYALEYSSKALDKFAENSHLILLDMVDVGKPDLVLTLLCRWLHMVHLYSSRTSITSWIYSIASKFYFIDSLNLETKDSVLESNWERFISSTETYELDSIRDSLIDCLIRLLCYSSNNAIDPVSAPGNLDFDNSAELCSSLTRFTPKNIDFVLKSLIHIPIHSITKNQRTRLLNLLIIHEKLLSDKDNSAHISLRKIIYTLMKTPCSSGFYRDPKIIIDLMQFGKTDLSFHKVHVLIMRSWIQHLDEGNKSEVILKLLQLILADFRELPLETITLIFNALVDSLPTSKHIKNSNDILSSVFTINDMLIDEMTAYLSKKESLCSGTFSCLLACCNSVLRTQNLTSESLNKLHILKVGIEEKAISLKLNELPFLENWILFQCLLSFGGDDFLKVVAYMVYYRRTVGEMSFRVSDFELALSRLSTNDADYAILNILNLLTSNECDEFDYSVLMKVVGVFANYSDCFQRNRHLVHMVLLCCTHVFYNQTLKPATLIDSALDVFLCFVQKTSKFISLDSFNTILTALSTILNLKELECEPKDHANLILKIIQILNGLLFNHRSYMSGRFHVFYSILKSLLYSMVQHDSEMKKIKGIALMNFYKPKKVPIHVVQSFCRLLTTWMNPNLMHDSNKKNSSLTDAERLFVKATTKHFVFLLTDFMSAQTVYQIDIQVKELLTNCFYNVYENLSNHEKQMALVAMNAPSKSLYQKFVNDYLIFAKWNEA

Protein

Probable nucleolar pre-ribosomal-associated protein 2: urb2

Gene

URB2

Protein

Nucleolar pre-ribosomal-associated protein 2

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

1174 amino acids

Function

Required for 27S pre-rRNA processing. Has an early role during 60S ribosomal subunit assembly.

Mass

135.118 kDa

Sequence

MGDLTEELSIPDNAQDLSKLLRSTSTKPHQIAEIVSKFDKLETYFPKKEIFVLDLLIDRLNNGNLDDFKTSEHTWIIFTRLLDAINDPISIKKLLKKLKTVPVMIRTFFLWPKDKLLTRSVSFIKAFFAINDYLIVNFSVEESFQLLEHAINGLSSCPTTDFALSYLQDACNLTHVDNITTTDNKIATCYCKHMLLPSLRYFAQTKNSASSNQSFIRLSHFMGKFLLQPRIDYMKLNKKFVQENASEITDDMAYYYFATFVTFLSKDNFAQLEVIFTILGAKKPSLECRFLNLLSESKKTVSQEFLEALLLEMLASTDESGVLSLIPIILKLDIEVAIKHIFRLLELIQLENLNDPLFSSHIWDLIIQSHANARELSDFFAKINEYCSRKGPDSYFLINHPAYVKSITKQLFTLSSLQWKNLLQALLDQVNHDSTNRVPLYLIRICLEGLSEGASRATLDEVKPILSQVFTLESFNNSLQWDLKYHIMEVYDDIVPAEELEKIDYVLSSNIFDTTSADVEELFFYCFKLREYISFDLSDAKKKFMRHFEILDEERKSNLSYSVVSKFATLVNNNFTREQISSLIDSLLLNSTNLSSLLKNDDIFEETNITYALINKLASSYHQTFALEALIQIPIQCINKNVRVALINNLTCESFCLDSATRECLLHLLSSPTFKSNIETNFYELCEKTIMSPEMAISETGDEKKEIEDKISIFEKVWTNHLSQAKEPVSEKFLESGYDIVKQSMSLSNGDSKLIIAGFTIAKFLKPDNKHRDIQGMAISYAVKILENYSENFESETIPLFRISMSTLYKIITTGQGDISKHKSRILDIFSKIMLRYHSKKVYHAPEEQEMFLVHSLLTENKLEYIFAEYLNIEHTDKCDSALGFCLEESLKQGPDAFNRLLWNSAKSFSTISQPCAEKFVRVFIIMSKRIARDNNLGHHLFVIALLEAYTYCDIEKFGYKSYLLLFNAIKEFLVSKPWLFSQYCIEMLLPFCLKTLAFIVNHESTDEINEGFINIIEVIDHMLLVHRFKFSNRHHLFNSVLCQILEIIAIHDGTLCANSADAVARLITNYCEPYNVSNAQNGQKNNLSSKISLIKQSIRKNVLVVLTKYIQLSITTQFSLNIKKSLQPGIHAIFDILSQNELNQLNAFLDTPGKQYFKALYLQYKKVGKWRED

Protein

Nucleolar pre-ribosomal-associated protein 2: URB2