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UL7

Gene
UL7
Protein
Cytoplasmic envelopment protein 1
Organism
Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997)
Length
388 amino acids
Function
Plays a critical role in cytoplasmic virus egress. Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm.
Similarity
Belongs to the herpesviridae cytoplasmic envelopment protein 1 family.
Mass
43.015 kDa
Sequence
MSVESSSAPGSVPTTSTVRKPRPGRETTREKSGTSPIEACVEAAPRANVSSGSGARTMANWAKETCDAVCHGGGARRRTPLERISEADEDAEECGNSANLPTRYEFANMLARGMPTAELVRAVVAHVIPRFFFEIRTAPGMPVVFAADSVSAILVGRDGSEMELELVSGTSMTMEDYFDAYLEMDNHLGFVFSVLTGAEDRVGSVALTWTELIDRMYVIQPNTSVDFSLCVLCMYLENVAEEDVTLSHCVMLKAALDKLKRKITFHAKVAALLANGCEWLLNTLMAMHDLPAFDRELILPHYGVAKPLMSVESEGLEELIRGLYDTHTITVINMPEPGHSDVQIMLEARKSTLNRVYENGNYYSRVLRLWWNTPLKRKNAYAMYHVYK
Protein
Cytoplasmic envelopment protein 1: UL7

Gene
UL7
Protein
Cytoplasmic envelopment protein 1
Organism
Human herpesvirus 1 (strain 17)
Length
296 amino acids
Function
Plays a critical role in cytoplasmic virus egress. Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm.
Similarity
Belongs to the herpesviridae cytoplasmic envelopment protein 1 family.
Mass
33.059 kDa
Sequence
MAAATADDEGSAATILKQAIAGDRSLVEAAEAISQQTLLRLACEVRQVGDRQPRFTATSIARVDVAPGCRLRFVLDGSPEDAYVTSEDYFKRCCGQSSYRGFAVAVLTANEDHVHSLAVPPLVLLHRFSLFNPRDLLDFELACLLMYLENCPRSHATPSTFAKVLAWLGVAGRRTSPFERVRCLFLRSCHWVLNTLMFMVYVKPFDDEFVLPHWYMARYLLANNPPPVLSALFCATPTSSSFRLPGPPPRSDCVAYNPAGIMGSCWASEEVRAPLVYWWLSETPKRQTSSLFYQFC
Protein
Cytoplasmic envelopment protein 1: UL7

Gene
UL7
Protein
Cytoplasmic envelopment protein 1
Organism
Human herpesvirus 2 (strain HG52)
Length
296 amino acids
Function
Plays a critical role in cytoplasmic virus egress. Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm.
Similarity
Belongs to the herpesviridae cytoplasmic envelopment protein 1 family.
Mass
32.967 kDa
Sequence
MADPTPADEGTAAAILKQAIAGDRSLVEVAEGISNQALLRMACEVRQVSDRQPRFTATSVLRVDVTPRGRLRFVLDGSSDDAYVASEDYFKRCGDQPTYRGFAVVVLTANEDHVHSLAVPPLVLLHRLSLFRPTDLRDFELVCLLMYLENCPRSHATPSLFVKVSAWLGVVARHASPFERVRCLLLRSCHWILNTLMCMAGVKPFDDELVLPHWYMAHYLLANNPPPVLSALFCATPQSSALQLPGPVPRTDCVAYNPAGVMGSCWNSKDLRSALVYWWLSGSPKRRTSSLFYRFC
Protein
Cytoplasmic envelopment protein 1: UL7

Gene
UL7
Protein
CEACAM1-like protein UL7
Organism
Human cytomegalovirus (strain AD169)
Length
222 amino acids
Function
Plays a role in modulating the host immune response and affecting host cytokine production. Structurally and functionally homolog of host CEACAM1, induces endothelial cell angiogenesis (PubMed:21670740). Ligands for host FLT3 receptor, activates the PI3K/AKT and MAPK/ERK pathways. In turn, triggers hematopoietic progenitor cell and monocyte differentiation leading to virus reactivation (PubMed:29691342).
Similarity
Belongs to the RL11 family.
Mass
24.353 kDa
Sequence
MASDVSSHLLTVTQSRWTIHHMYNKLLILALFTPVILESIIYVSGPQGGNVTLVSNFTSNISARWFRWDGNDSHLICFYKRGEGLSTPYVGLSLSCAANQITIFNLTLNDSGRYGAEGFTRSGENETFLWYNLTVKPKPLETTTASNVTTIVTTTPTVIGTKSNVTGNASLAPQLRAVAGFLNQTPRENNTHLALVGVIVFIALIVVCIMGWWKLLCSKPKL
Protein
CEACAM1-like protein UL7: UL7

Gene
UL7
Protein
CEACAM1-like protein UL7
Organism
Human cytomegalovirus (strain Merlin)
Length
222 amino acids
Function
Plays a role in modulating the host immune response and affecting host cytokine production. Structurally and functionally homolog of host CEACAM1, induces endothelial cell angiogenesis.
Similarity
Belongs to the RL11 family.
Mass
24.322 kDa
Sequence
MASDVGSHPLTVTRFRCRVHYVYNKLLILTLFAPVILESVIYVSGPQGGNVTLVSNFTSNISARWFRWDGNDSHLICFYKRGEGLSTPYVGLSLSCAANQITIFNLTLNDSGRYGAEGFTRSGENETFLWYNLTVKPKPLETTPASNVTTIVTTTSTVTDAKSNVTGNVSLAPQLRAVAGFSHQTPLENNTHLALVGVVVFLVLIVVCIMGWWKLLCSKSEL
Protein
CEACAM1-like protein UL7: UL7