Function
Glycosyltransferase that possesses phloretin 2'-O-glycosyltransferase activity. Converts phloretin to phlorizin (phloretin 2'-O-glucoside), a potent antioxidant. Is specific for phloretin and does not possess glycosyltransferase activity toward naringenin, naringenin chalcone, eriodictyol, eriodictyol chalcone, apigenin, luteolin, kaempferol, quercetin, isoliquiritigenin, butein, caffeic acid, 2-coumaric acid, 3-coumaric acid, 3-hydroxybenzoic acid, 3,4-dihydroxybenzoic acid and 3,4-dihydroxyhydrocinnamic acid (Ref.1). Can glycosylate phloretin in the presence of UDP-glucose, UDP-xylose and UDP-galactose (By similarity).
Sequence
MGDVIVLYASPGMGHIVAMVELGKFIVHRYGPHKFSITILYTCGSIVDTASIPVYIRRISHSHPFISFRQFPRVTNNITRNISVPAITFDFIRQNDPHVRSALQEISKSATVRAFIIDLFCTSALPIGKEFNIPTYYFHTSGAAVLAAFLYLPKIDEQTKTTESFKDLRDTVFEFPGWKSPLKATHMVQLVLDRNDPAYSDMIYFCSHLPKSNGIIVNTFEELEPPSVLQAIAGGLCVPDGPTPPVYYVGPLIEEEKELSKDADAAEKEDCLSWLDKQPSRSVLFLCFGSMGSFPAAQLKEIANGLEASGQRFLWVVKKPPVEEKSKQVHGVDDFDLKGVLPEGFLERTADRGMVVKSWAPQVVVLKKESVGGFVTHCGWNSVLEAVVAGVPMIAWPLYAEQHMNRNVLVTDMEIAIGVEQRDEEGGFVSGEEVERRVRELMESEGGRALRERCKKLGEMASAALGETGSSTRNLVNFVSSIT