UGT74AE2

Gene

UGT74AE2

Protein

UDP-glucosyltransferase 74AE2

Organism

Panax ginseng

Length

451 amino acids

Function

Component of the dammarane-type triterpene saponins (e.g. PPD-type ginsenosides or panaxosides) biosynthetic pathway (PubMed:25320211, PubMed:27746309, PubMed:29378087). Glycosyltransferase that catalyzes the biosynthesis of ginsenoside Rh2 from protopanaxadiol (PPD) and the conversion of compound K to ginsenoside F2 (PubMed:25320211, PubMed:27746309).

Similarity

Belongs to the UDP-glycosyltransferase family.

Mass

50.206 kDa

Sequence

MLSKTHIMFIPFPAQGHMSPMMQFAKRLAWKGVRITIVLPAQIRDSMQITNSLINTECISFDFDKDDGMPYSMQAYMGVVKLKVTNKLSDLLEKQKTNGYPVNLLVVDSLYPSRVEMCHQLGVKGAPFFTHSCAVGAIYYNAHLGKLKIPPEEGLTSVSLPSIPLLGRDDLPIIRTGTFPDLFEHLGNQFSDLDKADWIFFNTFDKLENEEAKWLSSQWPITSIGPLIPSMYLDKQLPNDKGNGINLYKADVGSCIKWLDAKDPGSVVYASFGSVKHNFGDDYMDEVAWGLLHSKYNFIWVVIEPERTKLSSDFLAEAEEKGLIVSWCPQLEVLSHKSIGSFMTHCGWNSTVEALSLGVPMVAVPQQFDQPVNAKYIVDVWQIGVRVPIGEDGVVLRGEVANCIKDVMEGEIGDELRGNALKWKGLAVEAMEKGGSSDKNIDEFISKLVSS

Protein

UDP-glucosyltransferase 74AE2: UGT74AE2