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UGT43

Gene
UGT43
Protein
UDP-glycosyltransferase 43
Organism
Pueraria montana var. lobata
Length
469 amino acids
Function
Glycosyltransferase that catalyzes the C-glucosylation of daidzein to puerarin (PubMed:28207970). Shows activity with the isoflavones daidzein and genistein, but has no activity towards flavonoids such as 2-hydroxynaringenin (PubMed:28207970). Can use UDP-glucose, but not UDP-galactose or UDP-glucuronic acid as sugar donor (PubMed:28207970). Does not require bivalent cations for activity (PubMed:28207970).
Similarity
Belongs to the UDP-glycosyltransferase family.
Mass
52.437 kDa
Sequence
MTRYEVVFIAIPTLGNLVPQVEFANLLTKHDPRFSATILTVSMPQRPLMNTYVQARASSAANIKLLQLPIVDPPAPEQYQTLVGFLSLHMQNHKHHVKHALLNLMKTTESNSSNSVRLAAIFVDMFSTTLIDVAAELAVPCYLFFASPASCLGFTLDLPRFDLAESKSEFTVPCFKNLLPRSVFPNLVLDAKDGTFWLSYHARRYKETKGIVINTLQELETHALQSLHNDSQLQRVYPIGPILDLVGSAQWDPNPAQYKRIMEWLDQQPLSSVVLLCFGSMGSLEANQVEEIAIGLERAGVRFLWALRESPKAQLEYPRDYENHKDVLPDGFLERTNNIGLVCGWVPQAVVLAHKAVGGFVSHCGWNSILESLWHGVPVATWPLYSEQQMNAFQMVRDLGLAVEISVDYRVGADLVRAEEVENGLRSLMKGGDEIRRKVKEMSDTCRGALLENGSSYSNLVSLIQELTS