UGLYAH

Probable (S)-ureidoglycine aminohydrolase

309 amino acids

Involved in the catabolism of purine nucleotides. The sequential activity of AAH, UGLYAH and UAH allows a complete purine breakdown without the intermediate generation of urea.

Belongs to the UGHY family.

34.106 kDa

MMLPRLLLLVVASALPLASVAAGAVGVGEGFCSAEPSAASGGCSGVRPPLYWKATNPTLAPAHLQDLPGFTRSVYKRDHALITPESHVFSPLPDWINTLGAYLISPAIGAHFTMYLAKMHDGSKSALPPKGVERLIFVLQGSILLSEESGNTHTLLVDSYAYLPANMKHSVISDEVTTLVIFERRYTTIEGYHPDLIVGSTDKQPLLETPGEVFELRKLLPTSLPYDFNIHIMDFQPGEYLNVKEVHYNQHGLLLLEGQGIYRLGDSWYPVQSGDTIWMAPFVPQWYAALGKTKTRYLLYKDVNRDPLI

UGLYAH

(S)-ureidoglycine aminohydrolase

298 amino acids

Involved in the catabolism of purine nucleotides. Can use (S)-2-ureidoglycine as substrate, but not allantoate. The sequential activity of AAH, UGLYAH and UAH allows a complete purine breakdown without the intermediate generation of urea.

Belongs to the UGHY family.

33.673 kDa

MRSLYLIVFIVISLVKASKSDDGFCSAPSIVESDEKTNPIYWKATNPTLSPSHLQDLPGFTRSVYKRDHALITPESHVYSPLPDWTNTLGAYLITPATGSHFVMYLAKMKEMSSSGLPPQDIERLIFVVEGAVTLTNTSSSSKKLTVDSYAYLPPNFHHSLDCVESATLVVFERRYEYLGSHTTELIVGSTDKQPLLETPGEVFELRKLLPMSVAYDFNIHTMDFQPGEFLNVKEVHYNQHGLLLLEGQGIYRLGDNWYPVQAGDVIWMAPFVPQWYAALGKTRSRYLLYKDVNRNPL