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UGAT

Gene
UGAT
Protein
Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase
Organism
Bellis perennis
Length
438 amino acids
Function
Involved in the production of glucuronosylated anthocyanins that are the origin of the red coloration of flowers. Can use cyanidin 3-O-6''-O-malonylglucoside, cyanidin 3-O-glucoside and delphinidin 3-O-glucosideas substrates, but not pelargonidin 3-O-glucoside, cyanidin 3-O-3'',6''-O-dimalonylglucoside, pelargonidin 3,5-O-diglucoside, pelargonidin 3-O-6''-O-malonylglucoside-5-O-glucoside, quercetin 3-O-glucoside, quercetin 3-O-6''-O-malonylglucoside, daidzin, genistin,7-O-6''-O-malonylglucosides of daidzein and genistein, cyanidin, quercetin, daidzein, genistein p-Nitrophenyl beta-D-glucopyranoside, beta-estradiol, 17alpha-estradiol, 1-naphthol, 2-naphthol, 4-methylumbelliferone, and p-nitrophenol. Highly specific for UDP-glucuronate (UDP-GlcUA). Arg-25 is decisive with respect to UDP-sugar specificity.
Similarity
Belongs to the UDP-glycosyltransferase family.
Mass
49.645 kDa
Sequence
MDSKIDSKTFRVVMLPWLAYSHISRFLVFAKRLTNHNFHIYICSSQTNMQYLKNNLTSQYSKSIQLIELNLPSSSELPLQYHTTHGLPPHLTKTLSDDYQKSGPDFETILIKLNPHLVIYDFNQLWAPEVASTLHIPSIQLLSGCVALYALDAHLYTKPLDENLAKFPFPEIYPKNRDIPKGGSKYIERFVDCMRRSCEIILVRSTMELEGKYIDYLSKTLGKKVLPVGPLVQEASLLQDDHIWIMKWLDKKEESSVVFVCFGSEYILSDNEIEDIAYGLELSQVSFVWAIRAKTSALNGFIDRVGDKGLVIDKWVPQANILSHSSTGGFISHCGWSSTMESIRYGVPIIAMPMQFDQPYNARLMETVGAGIEVGRDGEGRLKREEIAAVVRKVVVEDSGESIREKAKELGEIMKKNMEAEVDGIVIENLVKLCEMNN