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UBE2F

Gene
UBE2F
Protein
NEDD8-conjugating enzyme UBE2F
Organism
Bos taurus
Length
185 amino acids
Function
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
Similarity
Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.
Mass
21.133 kDa
Sequence
MLTLASKLKRDDGLKGSRASATASDSTRRVSVRDRLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTRIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVEDYIKRYAR

Gene
UBE2F
Protein
NEDD8-conjugating enzyme UBE2F
Organism
Gallus gallus
Length
185 amino acids
Function
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
Similarity
Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.
Mass
21.229 kDa
Sequence
MLTLASKLKRDDGVRGPRASNPASDSTRRVSVRDKLLVKEVAELEANLPCTCKVNFPDPNKLHYFQLTVIPDEGYYQGGKFQFEIEVPDAYNMVPPKVKCLTRIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVEDYIKRYAR

Gene
ube2f
Protein
NEDD8-conjugating enzyme UBE2F
Organism
Danio rerio
Length
185 amino acids
Function
Accepts the ubiquitin-like protein NEDD8 from the uba3-nae1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase rbx2, but not rbx1, suggests that the rbx2-ube2f complex neddylates specific target proteins, such as cul5.
Similarity
Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.
Mass
21.019 kDa
Sequence
MLTLASKLKREEGVRAGRTPAGSNDAAHRVSIRDRLLIKEVAELEANLPSTCKVTFPDENKLCHFQLAISPDEGYYLGGKFQFEIEVPEAYNMVPPKVKCLTRIWHPNIAETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIDAAEHHLRDKEDFRNKVQDFIKNYAR

Gene
UBE2F
Protein
NEDD8-conjugating enzyme UBE2F
Organism
Homo sapiens
Length
185 amino acids
Function
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
Similarity
Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.
Mass
21.077 kDa
Sequence
MLTLASKLKRDDGLKGSRTAATASDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYIKRYAR

Gene
Ube2f
Protein
NEDD8-conjugating enzyme UBE2F
Organism
Rattus norvegicus
Length
185 amino acids
Function
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
Similarity
Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.
Mass
21.08 kDa
Sequence
MLTLASKLKRDDGLKGSRASASTSDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVSPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRDKVDEYIKRYAR

Gene
ube2f
Protein
NEDD8-conjugating enzyme UBE2F
Organism
Xenopus laevis
Length
185 amino acids
Function
Accepts the ubiquitin-like protein NEDD8 from the uba3-nae1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase rbx2, but not rbx1, suggests that the rbx2-ube2f complex neddylates specific target proteins, such as cul5.
Similarity
Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.
Mass
21.397 kDa
Sequence
MLTLASKLKRDDGVKGSRTTSTTLDSMRRISVRDRLLVKEVAELEANLPCTCKVNFPDPNKLHYFHLTVSPDESYYQGGRFQFEIEVPDAYNMVPPKVKCLTRIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKDEYRNKVEDYIKRYAR

Gene
ube2f
Protein
NEDD8-conjugating enzyme UBE2F
Organism
Xenopus tropicalis
Length
185 amino acids
Function
Accepts the ubiquitin-like protein NEDD8 from the uba3-nae1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase rbx2, but not rbx1, suggests that the rbx2-ube2f complex neddylates specific target proteins, such as cul5.
Similarity
Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.
Mass
21.313 kDa
Sequence
MLTLASKLKRDDGVKGSRTSSTTSDSTRRVSVRDRLLVKEVAELEANLPCTCKVNFPDPNKLHYFHLTVSPDESYYQGGRFQFEIEVPDAYNMVPPKVKCLTRIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKDEYRNKVEDYIKRYAR

Gene
Ube2f
Protein
NEDD8-conjugating enzyme UBE2F
Organism
Mus musculus
Length
185 amino acids
Function
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
Similarity
Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.
Mass
21.11 kDa
Sequence
MLTLASKLKRDDGLKGSRTSASTSDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVSPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRDKVDEYIKRYAR