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U65

Gene
U65
Protein
Cytoplasmic envelopment protein 2
Organism
Human herpesvirus 6A (strain Uganda-1102)
Length
335 amino acids
Function
Plays a critical role in cytoplasmic virus egress. Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm by directly interacting with the capsid. Upon virion binding to target cell, a signaling cascade is triggered to disrupt the interaction with the capsid, thereby preparing capsid uncoating.
Similarity
Belongs to the herpesviridae cytoplasmic envelopment protein 2 family.
Mass
37.877 kDa
Sequence
MAISTFSIGDLGYLRNFLQNECNWFRICKKTFYREYRSVATSSPTFSLNNKPKKFCMHCEIVIFKRSEEFMFSLAVNGIHFGQFLTGKMKFNKKAVPEGLYYYILELGSITPIDLGFIPRYNSDCVTNMRCVTPEVIYENCSIVCPEEANRLTVKGSGDNKLTPLGGCGAWCLKNGGDLYIYTFALAYDLFLTCYDKSTFPSLAKIIFDMIACESEDCVFCKDHNKHVSQAGQIVGCVSNQETCFCYTSCKKKMANINNPELISLLCDQEINKIDIMYPKIKASLSLDINSYAHGYFGDDPYALKCVNWIPVRISAALSRLIVLSCPVCKRVVMD

Gene
U65
Protein
Cytoplasmic envelopment protein 2
Organism
Human herpesvirus 6B (strain Z29)
Length
335 amino acids
Function
Plays a critical role in cytoplasmic virus egress. Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm by directly interacting with the capsid. Upon virion binding to target cell, a signaling cascade is triggered to disrupt the interaction with the capsid, thereby preparing capsid uncoating.
Similarity
Belongs to the herpesviridae cytoplasmic envelopment protein 2 family.
Mass
37.878 kDa
Sequence
MAISTFSIGDLGYLRNFLQNECNWFRICKKTFYREYRSVATSSPIFSLKNKPKKYCMHCEMVVLKRSHEFMFSLAVNGIHFGQFLTGIMKFKKKQVAEGLCYYVLELGSISPVDLSFIPKYNSDCVTSMHCVTPELIYENCSIVCPEEASRLTVKGLGDNKLIPLGGCGVWCLKNGGDLYIYAFVLAYDLYVACYDKTIFPSLAKIVFDMIACDSEDCVFCKDHNKHVSQAGHIVGCVSNQETCFCYTPCQKKMTDINNPELISLLCDQEINKIDIMYPEKKASLSLDINSYVHGYLGDEPCALKCVNWMPIRISSALSRLIILSCPVCKRVVMD

Gene
U65
Protein
Cytoplasmic envelopment protein 2
Organism
Human herpesvirus 7 (strain JI)
Length
330 amino acids
Function
Plays a critical role in cytoplasmic virus egress. Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm by directly interacting with the capsid. Upon virion binding to target cell, a signaling cascade is triggered to disrupt the interaction with the capsid, thereby preparing capsid uncoating.
Similarity
Belongs to the herpesviridae cytoplasmic envelopment protein 2 family.
Mass
37.498 kDa
Sequence
MNFSSIGNLGCLRSFLQNECNWFSVCKKKLYHEYRCVATSSPVFAVDKFKDCLHCNIIILKKNLDFVFSLAINGIHAGQFATNSIKLKKIIITNDLVYYILELGSLTVTDLHFIPKYNSEHVLNVRPITPNLIYDTCSIVSYDEAKLLTVKGPGENKLIPLGCGSWCLNNMGRYYVYTFVLVYDLYLACFEKNTLPSLSKVVFDMISCNNKHCVFCKDHSKHVEQTGKTVGCTDNQETCFCYTPCKKKMAKISNQDLSSLLCDQELDLLDLIYPEKPTSLSTDINAYVHGHKNQEPVVLRNTNWILIRLDPAISRLILLSCPVCKRIVSR