About Products Protein Database Contact

Tbrg1

Gene
TBRG1
Protein
Transforming growth factor beta regulator 1
Organism
Homo sapiens
Length
411 amino acids
Function
Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.
Similarity
Belongs to the TBRG1 family.
Mass
44.946 kDa
Sequence
MSLLDGLASSPRAPLQSSKARMKKLPKKSQNEKYRLKYLRLRKAAKATVFENAAICDEIARLEEKFLKAKEERRYLLKKLLQLQALTEGEVQAAAPSHSSSLPLTYGVASSVGTIQGAGPISGPSTGAEEPFGKKTKKEKKEKGKENNKLEVLKKTCKKKKMAGGARKLVQPIALDPSGRPVFPIGLGGLTVYSLGEIITDRPGFHDESAIYPVGYCSTRIYASMKCPDQKCLYTCQIKDGGVQPQFEIVPEDDPQNAIVSSSADACHAELLRTISTTMGKLMPNLLPAGADFFGFSHPAIHNLIQSCPGARKCINYQWVKFDVCKPGDGQLPEGLPENDAAMSFEAFQRQIFDEDQNDPLLPGSLDLPELQPAAFVSSYQPMYLTHEPLVDTHLQHLKSPSQGSPIQSSD
Protein
Transforming growth factor beta regulator 1: TBRG1

Gene
tbrg1
Protein
Transforming growth factor beta regulator 1
Organism
Xenopus tropicalis
Length
409 amino acids
Function
May act as a growth inhibitor. May be involved in maintaining chromosomal stability.
Similarity
Belongs to the TBRG1 family.
Mass
45.785 kDa
Sequence
MNHSPATTFSPHSRYQELKVRNKKSTKKSHKEKYRLKCLRLRRVAKDMVFENAALCDEIARTEDKFIRAKEERRFLLKRLLQLQALSEEEPGTSHNSNVSAGYSVPDMAAMNEGNLDMCYSSVLDDGGSCKKVKKDKREKGKENKSEAMKKPSKKKRVTEGTTRKWVQPIALDPCGRPVFPIVLEGLTVYSLGEIISDRAGFHEKVAIYPVGFCSTRVYVGMKNPDQKCLYTCQIKDGGTGPQFEIVPDDDPQNSIVASSADECHSILLQKISTPLGKRFSTPDLAGAYFFGFTHPTIQNLIQSCPGARKCTGYQWVKFEVCRAGEEQVPRDICESSASVNFEAFQRQSFATINNSTALAGTLDLPEIHASHDYISTYQEIFLSHSQLASGMQHLKSPSNQYSPSRSSE
Protein
Transforming growth factor beta regulator 1: tbrg1

Gene
Tbrg1
Protein
Transforming growth factor beta regulator 1
Organism
Mus musculus
Length
406 amino acids
Function
Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.
Similarity
Belongs to the TBRG1 family.
Mass
44.881 kDa
Sequence
MSVLSGLASEPRTPLSSKARMKRLPRKSQNEKYRLKYLRLRRAAKATVFENASICDEIARLEEKFLKAKEERRYLLKKLLQIHALTEGEPQAAAPSHSSSLPLPYGVTSSVGTMQGAGPSTGAEEPFAKKSKKEKKEKGKENSKLEVLKKTSKKKKMEGGARKLVRPIALDPSGQPVFPIGLGGLTVYSLGEIITNRPGFHDENAIYPVGYCSTRVYASMKCPDQKCLYTCQIKDGGVQPQFEIVPEDDPQNTIVGSSADACYEELLRAISATTGKLMPNPLSCGADFFGFSHPTIHNLIQSCPEAQNCVNYQWVKFDACKPRKGQLSQELPENDATMSLEAFQTQTFDDDHDDSILPGSLDLPELQHEAFVSSYQPEFLTHEPLVDTDLQHLKSPSQCSPIQSSD
Protein
Transforming growth factor beta regulator 1: Tbrg1

Gene
Tbrg1
Protein
Transforming growth factor beta regulator 1
Organism
Rattus norvegicus
Length
406 amino acids
Function
Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability (By similarity).
Similarity
Belongs to the TBRG1 family.
Mass
44.785 kDa
Sequence
MSVLSGLASEPRTPLSSKARMKRLPKKNQNEKYRLKYLRLRRAAKATVFENAAVCDEIARLEEKFLKAKEERRYLLKKLLQIHALTEGEPQAAAPSHSSSLPLAYGVTSSVGTIQGAGPSTGAEEPFAKKSKKEKKEKGKENSKLEVLKKTSKRKKMEGGARKLVRPIALDPSGQPVFPIGLGGLTVYSLGEIITNRPGFHDENAIYPVGYCSTRVYASMKCPDQKCLYTCQIKDGGVQPQFEIVPEDDPRNTIVGSSADACYEELLRAISAATGKLMPNPLSCGADFFGFSHPTIHNLIQSCPEAQNCVNYQWVKFDACKPRKGQLSQELPENDAAMSLEAFPTQTFDDDHEDSILPGSLDLPELQHEAFVSSYQPEFLTHEPLVDTDLQHLKSPSQCSPIQSSD
Protein
Transforming growth factor beta regulator 1: Tbrg1