Protein
Adenylosuccinate synthetase
Organism
Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)
Function
Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
Similarity
Belongs to the adenylosuccinate synthetase family.
Sequence
MAAAPSATAPKHNYTLGTNASQLELYKYLKTVPPIPELRQAVTIKKYEEASVDDTLYPLIDEHQIIMVVGAFFGDEGKGKTVDAVARHPACTCVARVNSGENAGHTVFDDIGRKYVFNLAPSSLLTPNTRNYVSSECVMDPISFMEREIGQFIKSNMPYKDKLFVGNVFVVTPYHKLLDLLGSAPNSSTLKGMSPIHASKVTKRGIRLDHIFNDEGVLRARLAKDMDTYYGLLKVKGLTDKDVVRRCEEENADGVERVPGYVVDFARAENKIDYLVKLYTERVKNNKDFPRRCDVTHELRAALARGEKLLLEGPQSYWLSNAREKFWESTTSADTTAGGLLASAQFNFQRYKVLVINVHKAPGSSRVGIGANPSSFVPQDYYSAQDIKTLEALPKGGCVDFDKIQNFFYTKAFNTESKTFNGIYEPLEYEDATGKYNIGVAMSIASARHHGECGAVTKKPRVCGFFDCVLHFEVNAVQGPYLSISAVDRGDDYDRIGITIAYVYYDVGNKMVDANGRVYKNGDIIKAGDPVPCEMALYHCYPIVKVINGWKGAPIAASKRRPNEPLPKGVCEFIANVEFFTGAKVISIGNGPRGSDIIYLKQ