Protein
Bifunctional phosphoglucose/phosphomannose isomerase
Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Function
Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency.
Similarity
Belongs to the PGI/PMI family.
Sequence
MLRSHCMEFSEELKTLKDQVRFDGSFRTGTFSNIVIAGMGGSGIAGRIFSEMYSAKPVFVCDDYHIPEFVDGNTEFIAVSYSGNTEETLSAAEEAIKKGAKVHAITSGGRLSEMGVDTIKIPGGLQPRSAVGYLTMPIINTFIRPKHEDIEEAAGLLSDLDKNNTVQENIATEIYAGRRIPVIYGSTPYRSVAYRWKTQFNENAKILAYSNYFSELNHNDTMPLRDTYRKDEFYFMAFDSTDERIRKRIEVTQKITGTSFKKIEARGSSLIARIFYLIHFGDYVTYHLARIRNVDPQDVSAIEDLKKRIS