TXNDC11

Thioredoxin domain-containing protein 11

985 amino acids

May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.

Belongs to the protein disulfide isomerase family.

110.529 kDa

MSECGGRGGGSSSSEDAEDEGGGGGGPAGSDCLSSSPTLATASSAGRLRRGLRGAFLMARQRPELLCGAVALGCALLLALKFTCSRAKDVIIPAKPPVSFFSLRSPVLDLFQGQLDYAEYVRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQKHFFYFPVIYLYHRSFGPIEYKGPMSAVYIEKFVRRVMKPLLYIPSQSELLDFLSNYEPGVLGYFEFSGSPQPPGYLTFFTSALHSLKKALESTSSPRALVSFTGEWHLETKIYVLDYLGTVRFGVITNKHLAKLVSLVHSGSVYLHRHFNTSLVFPREVLNYTAENICKWALENQETLFRWLRPHGGKSLLLNNELKKGPALFLFIPFNPLAESHPLIDEITEVALEYNNCHGDQVVERLLQHLRRVDAPVLESLALEVPAQLPDPPTITASPCCNTVVLPQWHSFSRTHNVCELCVNQTSGGMKPSSVSVPQCSFFEMAAALDSFYLKEQTFYHVASDSIECSNFLTSYSPFSYYTACCRTISRGVSGFIDSEQGVFEAPTVAFSSLEKKCEVDAPSSVPHIEENRYLFPEVDMTSTNFTGLSCRTNKTLNIYLLDSNLFWLYAERLGAPSSTQVKEFAAIVDVKEESHYILDPKQALMKLTLESFIQNFSVLYSPLKRHLIGSGSAQFPSQHLITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARIDVSQNDLPWEFMVDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSDPASSPQNVANSPTKECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVATMERKLEGRDGAESLAAQREVHPKQPEPSATPQLPGSSPPPANVSATLVSERNKENRTD

TXNDC11

Thioredoxin domain-containing protein 11

957 amino acids

May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation (By similarity).

Belongs to the protein disulfide isomerase family.

107.366 kDa

MSECGGRGGGGGSSSSSDDAEDEGGGGGPAGSGSLSPAPAASSEGRLRRGLRGASLMARRRPELLCGAVALGCALLLALKFTCSRAKDVIIPAKPPVSFFSSRSPVLDLFQGQLDYAEHIRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQKHFFYFPVIYLYHRSFGPIEYKGPMSAVYIEKFVRRVMKPLLYIPSQSELLDFLSNYEPGVLGYFEFSGSPQPPGYLTFFTSALHSLKKDYLGTVRFGVITNKHLAKLVSLVHSGSVYLHRHFNTSLVFPREVINYTAENICKWALENRETLVRWLWPHGGKSLLLNNELKKGPALFVFIPFNPLAESHPLIDEITEVALEYNNCHGDQVVERLLQHLRRVDAPAFKSLAPDPPARLPDPPLITASPCCNTVVLPRWHSISRTHNVCELCVNQTAGGLRPSSVSMPQCSFFEMAAALDSFYLKEQTFYHVVSDSIECSNFLSFYSPFSYYTACCRTINRGVAGFIDSEQGVFETPPVAFSSLEKKCEVESPGSVPHIEENRYLFPELETSSSSFTGLSCRTNKTLNIYLLDSNLFWLYAERLGAPSAARVKEFATIVDVKEESHYILDPKQALMKFTLESFIQNFSVLYSPLKRHLIGSDSTQFTSQRLITEVTTDTFWEVVLQKQDVLLLYYAQWCGFCPALNHVFIQLARLLPSDTFTVARIDVSQNDLPWEFMVDRLPTVLFFPCNRKDLSVKYPEDLPITLPNLLRFILHHSDPASDPRNLAGPPTAECLQNEAVLQQGHIAHLEREIRKLRAEIGTLQRAQVQVEARLASARRDEHRLLRQQHTLERQHDLLRLHSEQLQALYEHKTRELDEVARKLQELADASETLLTENTWLKILVATMEQRLEGRDGADDRVPPSKARSEHPEPPGAPRLPASTPLPANISSTLASEGSPENRTD

Txndc11

Thioredoxin domain-containing protein 11

948 amino acids

May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation (By similarity).

Belongs to the protein disulfide isomerase family.

105.959 kDa

MSECGGRGGGGGNNSEDAEDEGGGPKGSGSLSPAGAAASLEGRIRRGLRGASLMARQRPELLCGAVALGCALLFALKFTCSRAKDVIIPAKPPVSFFSSRSPVLDLFQGQLDYADHVRQDSEVVVLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQKHFFYFPVIHLYHRSFGPIEYKGPMSAVYIEKFVRRAMKPLLYIPSQSALLDFLSSYEPGVLGYFEFSGSPQPPGYLTFFTSALHSLKKDYLGTVRFGVITDKHLARLVSLVHSGSVYLHRHFNTSLVFPREVMNFTAENIYKWASENQETLFRWLQPHGGKSLLLNNELKKGPALFLFIPFDPLAERHPLLDEITEVALEYNNCHGDQVVERLLQHLRRVEAPVLQSLAPELPASLPDTQLMAASPCCNTVVLPQGPALSRTHNVCELCVNQTVGGTRPSSVSVPQCSFFEMAAALDSFYLKEQTFYHVVSGSIECSNFLTSYSPFSYYTACCRTISRGMASFTGSEQNVLTAPAIEFSSLEKSCEATAPSSIPHIEENRYRFPQVGLTSTAFTGLSCRTNKTLNIYLLDSNLFWLYAERLGAPSSAPVKEFATIVDVKEESHYILDPKQALMKFTLESFIQNFSVLYSPLKRHLTGSDSAQFPTQHLITEVTTDTFWEVTLRKQDVLLLYYTQWCGFCPSLNHIFIQLARLLPEDTFTVARIDVSQNDLPWEFMVDRLPTVLFFPCNRKDLSVKYPGDLPITLPNLLRFILHHSDAASAPQDPGISPPTQDCVQSKAVLQREHISHVENAMQKLRSEMSSLRRTQEQVEGRLLSARRDGHRLLRRQRTLEQQHRLLRRHSQKLQALYLKKARELQELARASGTPLPEHTWLKILVATMERELEGQGGAKEPAPLGKARPNHSKSMGTTQLPGDTPPPSTTSSTLASETKHENRTD