Protein
Archaeal Lon protease
Organism
Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Function
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively (By similarity).
Similarity
Belongs to the peptidase S16 family. Archaeal LonB subfamily.
Sequence
MEENIESVEEWVSKLDIETTKDIHVPKLLFDQVIGQDQAGEIVKKAALQRRHVILIGEPGTGKSMLAQSMVDFLPKSELEDILVFPNPEDPNKPKIKTVPAGKGKEIVRQYQIKAEREKRDRSRSIMFVIFSVVLLGIIAAIVLRSITLIFFAIMAAAFLYMAMAFNPVIRNEKAMVPKLLVSHSSTDKPPFVDSTGAHSGALLGDVRHDPFQSGGLETPAHERVEAGNIHKAHKGVLFIDEINLLRPEDQQAILTALQEKKYPISGQSERSAGAMVQTEPVPCDFVLVAAGNYDAIRNMHPALRSRIRGYGYEVVVNDYMDDNDENRKKLVQFIAQEVEKDKKIPHFDKSAIVEIIKEAQKRSGRRNKLTLRLRELGGLVRVAGDIAVSQKRNIVTASDVIAAKALSKPLEQQIADKSIEIKKIYKTFRTEGSVVGMVNGLAVVGADTGMAEYTGVVLPIVAEVTPAEHKGAGNIIATGKLGDIAKEAVLNVSAVFKKITGKDISNMDIHIQFVGTYEGVEGDSASVSIATAVISAIENIPVDQSVAMTGSLSVRGDVLPVGGVTAKVEAAIEAGMAKVIVPELNYNDIILDAEHINRIQIIPARTIEDVLKVALVNSPEKDKLFDRIASIINNAKIIKPQKPVASTRAGQNVA