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TULP4

Gene
Tulp4
Protein
Tubby-related protein 4
Organism
Mus musculus
Length
1547 amino acids
Function
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Similarity
Belongs to the TUB family.
Mass
169.638 kDa
Sequence
MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFTSSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGILSMSWNYPIFLVEDSSESDTDSDDYSPPQDGPAAYPIPVQNTKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLAVAGMEQQAQLSELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMASGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVNKLTLPPRLCSYLSTAFIPTIKPPIPDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKLRPEFVIMDPRTDSKSDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRSSKSPKLPRISIEARKSPKLPRAAQEISRSPRLPMRKPSMGSPSLTRREFPFEDITQHNYLAQVTSNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNPNVFSEDEDDLPVTGASGVPENNPPCTVNIPIAPIHSSAQALSPTQSIGLVQSLLANQNVQLDVLTNQTTAVGSAEHAGDAATQYPVSSRYSNPGQVIFGGVEMGRIIQNPPQLPLPPPPPPPPQAPMQLSAVDHGDRDHEHLQKSAKALRPVPQLAAEGDAVVFSAPQEVQVAKMNPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTAAHYQPPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCTSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRSAAQRLDNSLIHATLRRNNREVALKMAQLADSSRAPLQPLAKPKGGAAGAVAQLPARPPPALYTCSQCSGAGPSSQSGAALAHAISTSPLASQSSYNLLSPPDTSRDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTMKRPPPYQWDPMLGEDVWVPQERTAQPTVPNPLKLSPLMLGQGQHLDVARVPFVPPKSPSSPTATFPTGYGMGMPYPGSYNNPSLPGVQAPCSPKDALSQAQFAQQESAVVLQPAYPPSLSYCTLPPTYPGSSTCSSVQLPPIALHPWNSYSTCPPMQNTQGTLPPKPHLVVEKPLVSPPPAELQSHMGTEVMVETADNFQEVLSLTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVKKDARTLSDFNSLISSPRLGREKKKVKSQKDQLKSKKLNKTNEFQDSSESEPELFISGDELMNQSQGSKKGWKSKRSLRTASELEEFKCRKASEKEDGRLGSQGFVYVMANKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQVMQFGRIDGNAYILDFQYPFSAVQAFAVALANVTQRLK
Protein
Tubby-related protein 4: Tulp4

Gene
TULP4
Protein
Tubby-related protein 4
Organism
Homo sapiens
Length
1543 amino acids
Function
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Similarity
Belongs to the TUB family.
Mass
169 kDa
Sequence
MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFTSSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPPQDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLAVAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMASGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPIPDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKLRPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSPKLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVTSNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNPNVFSEDEDDLPVTGASGVPENSPPCTVNIPIAPIHSSAQAMSPTQSIGLVQSLLANQNVQLDVLTNQTTAVGTAEHAGDSATQYPVSNRYSNPGQVIFGSVEMGRIIQNPPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQNPQGTLPPKPHLVVEKPLVSPPPADLQSHLGTEVMVETADNFQEVLSLTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVKKEARTLSDFNSLISSPHLGREKKKVKSQKDQLKSKKLNKTNEFQDSSESEPELFISGDELMNQSQGSRKGWKSKRSPRAAGELEEAKCRRASEKEDGRLGSQGFVYVMANKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQVMQFGRIDGSAYILDFQYPFSAVQAFAVALANVTQRLK
Protein
Tubby-related protein 4: TULP4

Gene
TULP4
Protein
Tubby-like protein 4
Organism
Oryza sativa subsp. japonica
Length
419 amino acids
Similarity
Belongs to the TUB family.
Mass
46.078 kDa
Sequence
MAATKREPLRPISSNAGTVERRARGGAAAAAAAKEKEKENEVPTEIGRGKDGGEKKPPVVVAVVVPPAPPLKPSSLQVRMKAEEEKEREEEEEGSSPAVALVAGLQVRMGPRGRELLLPPPPPPPPLPLPTSSSYEAWDLSDNEAAPASSWATLPNRALLCRPLPLDVGRCTCIIAKETLAAAAAGARGVALYSLYTNEGQGRQDRKLAVARHRRRRGRSEFVVAQNLDGIFCTSDKNFLGTLSSNLVGSRYRIWGQGNRVDEIKSQSKRLLGVVAFAPTVTTLTGSFRSMRAWIPKNQSIHLKNSNSAQIQHISGLPKDWQEKKIKADQLCSRSPFYNNMTKRYELDFRERAGRMGYKVQPSVKNFQMTLEEKGRQTILQLGRIGKSKYIMDFRYPLTGYQALCICLASIDSKLCCTL
Protein
Tubby-like protein 4: TULP4

Gene
TULP4
Protein
Putative Tubby-like protein 4
Organism
Arabidopsis thaliana
Length
265 amino acids
Similarity
Belongs to the TUB family.
Mass
30.184 kDa
Sequence
MPPELLRDVLMRIERSEDTWPSRKNVVSCVGVCKNWRQIFKEIVNVPEVSSKFTFPISLKQPGPGGSLVQCYVKRNRSNQTFYLYLGGEAKIFCQSEPSEPNKSIWKLSLKPGGTATTQTELDNFVSFRSPSGQKEGVLVLKSKVPRLEEQSWCLDFNGWRDIVSSGKKFQLVALLRTNLRMKTTFSSLRKSETCTNSSYEAEWIPLVRTSVFAVIARVCRDKKHTPSYELKLALYFAKNSAILKKFVLRGYTREEDLLALPVAN
Protein
Putative Tubby-like protein 4: TULP4