Protein
Probable alpha-tubulin polyglutamylase Ttll1
Organism
Tetrahymena thermophila (strain SB210)
Function
Probable tubulin polyglutamylase with a strong preference for alpha-tubulin. Modifies alpha-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha-tubulin.
Similarity
Belongs to the tubulin polyglutamylase family.
Sequence
MASKKLKYKTDFDKCVLTDNFAARGWTRCGDKDDDDWNIYWATVWNVRNIFNPKSGIRLNDMQIINHFPNHYELTRKDLMVKNFKRYKKELEKENSPYCQKDENGNYLYLDFIPQTFTLPGEYSLFVEEFHRNPNATWIVKPASRSQGKGIFLLRKIQQLKKIGGGTNSNPLQAFSLKEAYVVSRYIDNPLLVGGRKFDLRIYALVTSYRPLKVYLYAMGFGRFCNEQYTQDIAEMDNMFIHLTNVAIQKFSDKYSEKHGGKWSLQSLRYYLEMVYGTDMANKCFDDINNIIIMSLKSVQSIIINDKHCFEMYGYDILIDENCKPWLIEINASPSLTVTGKIDKELKTELIKNVYQIVIPDDWNDDSSKTGANTSTQTKVGDFNILYDEAQEKKISQQQQQQKKNINSKTIWK