TRM9

tRNA (carboxymethyluridine(34)-5-O)-methyltransferase

404 amino acids

Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA.

44.96 kDa

MILDVLRTFSTRTRNLPSSGFYSISTSIMRDIKVKSDSKEFLTSSDEEEESVSIRVSSSSSLSSVKSTPEIEKKYVHRVYDAIAPHFSSTRFAKWPKVAAFLESLPSGSVILDAGCGNGKYLGLNPSCFFIGCDISHPLIKICSDKGQEVLVADAVNLPYREEFGDAAISIAVLHHLSTENRRKKAIEELVRVVKPGGFVLITVWAAEQEDTSLLTKWTPLSAKYVEEWVGPGSPMNSPRVRNNPFFSLESIPETEVSTKEQKVENSQFIGLESIPESEESTREQKGESIIPETKASIVEQKDEKSVEESLEALKKSQQEYFVPWHLPYHRAEVSGASASALASGLAKKDDRKGAVVYNRYYHVFSEGELERLASGVGNAMIVDRFFDKSNWCIVLQKEALNQD

TRM9

tRNA (carboxymethyluridine(34)-5-O)-methyltransferase

279 amino acids

Required for the methylation of the wobble bases at position 34 in tRNA. Appears to have a role in stress-response.

32.439 kDa

MEINQAAEKEQEYVHKVYNEIAPHFSQTRYKPWPIVTQFLKTRPMGSIGIDVGCGNGKYLGVNPDIYIIGSDRSDGLIECARGINPSYNLLVADGLNLPHKNETFDFAISIAVVHHWSTRERRVEVIRHVLSKLRQGGQALIYCWALEQGSSRRGYHEGMEQDVFVPWVLPKSKSKPKTKSTPPAKVKTRPKPNLMNIPPKERSEYLQRWKEEQQRSKSLDDNDEKQQQDQEQEREEVKYRYYHLYREGELAEDCRQAGAAVHSEGFERDNWWVVAQKR

trm9

tRNA (carboxymethyluridine(34)-5-O)-methyltransferase

228 amino acids

Required for the methylation of the wobble bases at position 34 in tRNA. Appears to have a role in stress-response (By similarity).

26.277 kDa

MEIEYENEYVHQVYDKIATHFSDTRYKPWPVVEKFLKSLPLGSVGVDIGCGNGKYQKVNPNVYMIGSDRCVKLVKIASNLGPMVISDGLHVPHPSNRFDFALSIAVIHHFSNENRRLQAVQEVLRPLVKGGKALFFVWALEQKNSRRGFSEDGPQDVYVPWILKRQYEYPNAKPEELKGHDPAENIAYQRYYHLFRKGELNELVETAGGSILEHGYDRDNWWVIAEKN