TRM3

tRNA (guanosine(18)-2'-O)-methyltransferase

1436 amino acids

S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs.

Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

165.048 kDa

MVGGALICKYLPREEQLKLISDLIQNDSLEEVLELIETSPLDITTDSNIETPIFEKITEQVIAYASIDGEAREMFRSSRAEMNKALRTSAQLLCCLPSVWHKFQVWMSYRLNDIISENYKHLFNDNFGKKIVQPFFDSFAEEQNANIKHENLHLDILSLLHYLEVVYLFDECKNGISSKCLDFIIVPLLGCNSEEIADSCSKLMRWHIKYLSKCCNTDSNFDKLIWTFIKQLYAEGSQQAWKQKNSLSFLLRFLLAAELSPELITYIKTDAYWRHIQTELDNDVHEHRKLALSILKLTIQKLSSHGITLQTTFYKCNDLANIEMLGSWKKFTTLYEMIALDTSLNQIQAAKQDIIKIFDNEHLHHSWGLILLSTGLKSSMESVRKYMMTLMFSITNMSAFSSNLPLLTKTLLPAAMSAHYFDVKGVSCPHGEKLSLFVNNLLSQTTEGISDILFEILKLLVEKGTSFDPSRIYLSYGILVFFQNNKQKTINSDHLSLIRKLYDFAAEEEVLETTIQTIYLKFLLYIDPSVSASELLFTLVSHIKLKGGTYKYVEPLFEDYRDLAVSHFDDLQAKENLTTNIGKDTIFDLLASIIFDFKDIDITPDFLIEVAKSKQDIPVYTSKAVTFLTQLLSGEPSNGYTYENATALLSYPNFTISTWKSINVNNLFKSVMEKFSLDKFKFFAEIYQKTYECRFDTIELNFNDLLSLYEMVKKSANQCSRESFKVKDSAYSSYFELLNTFLKTYALNRDSSEGNDDELHILLRLVDENINKDNGNYLGNLAVCKLLYFIIDSYIHCSTSVSDDDIFIVKFIFEKFSFIWECINSERLVLKERDLHLMLIKGLFHPVILYFGSNQYIDTLTSKLEEHAQTIISLSYSRRSLLPLLGSQLRVFMKFYGKLLREDVNYWWLINIIVGVFKQPQMDVNLYKLKPVISSLFDHKLNNYYIKGDELYEKVYGPDEILARVSIIDSILYANDQLKIRLIEKVTEKTNALYAIKRTDGAEALQRLLQWQLLLLSLLTTNEKKLSETSMIRILKSIEDESSPLVRVYKEWFISSKVVDYYKTGNPKFAEDYLFSLLEDHSKPVFVVSAEKICFMVLKDLRNDEKKYGFTQLLDRFICTLVPNAASNKPLVRHFSNSLIISLWPTFKAYLSDHTLRNIIENLYSNAKKTQIFGQYRAGDANIWDLKGDRKLTNMFGGVLKKVTDHDCPYISESVFEKYLQEKDIVPIGTDERSLWLDKRDTNTESVNNANISCDTSPLQTKSGAWETVLDLDNKKSNDVVTRSELIVVSSLVDKPPNLGGICRLCDVLGVGLLTVQDIKVKNHPQFKNVAVTADRWMPMEEVALDEIASFMKEKKKEGYTLIGLEQTDKSVKLDNNFQFPKKSLILLGTEAFGIPGTLLSELDLCLEIQQFGVIRSMNIQTATAVIVHSYTVQHM

TRM3

Tripartite terminase subunit 3

747 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

82.757 kDa

MSLIMFGRTLGEESVRYFERLKRRRDERFGTLESPTPCSTRQGSLGNATQIPFLNFAIDVTRRHQAVIPGIGTLHNCCEYIPLFSATARRAMFGAFLSSTGYNCTPNVVLKPWRYSVNANVSPELKKAVSSVQFYEYSPEEAAPHRNAYSGVMNTFRAFSLSDSFCQLSTFTQRFSYLVETSFESIEECGSHGKRAKVDVPIYGRYKGTLELFQKMILMHTTHFISSVLLGDHADRVDCFLRTVFNTPSVSDSVLEHFKQKSTVFLVPRRHGKTWFLVPLIALVMATFRGIKVGYTAHIRKATEPVFEGIKSRLEQWFGANYVDHVKGESITFSFTDGSYSTAVFASSHNTNGIRGQDFNLLFVDEANFIRPDAVQTIVGFLNQTNCKIIFVSSTNTGKASTSFLYNLRGSSDQLLNVVTYVCDDHMPRVLAHSDVTACSCYVLNKPVFITMDGAMRRTADLFMADSFVQEIVGGRKQNSGGVGFDRPLFTKTARERFILYRPSTVANCAILSSVLYVYVDPAFTSNTRASGTGVAIVGRYKSDWIIFGLEHFFLRALTGTSSSEIGRCVTQCLGHILALHPNTFTNVHVSIEGNSSQDSAVAISLAIAQQFAVLEKGNVLSSAPVLLFYHSIPPGCSVAYPFFLLQKQKTPAVDYFVKRFNSGNIIASQELVSLTVKLGVDPVEYLCKQLDNLTEVIKGGMGNLDTKTYTGKGTTGTMSDDLMVALIMSVYIGSSCIPDSVFMPIK

TRM3

Tripartite terminase subunit 3

737 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

82.648 kDa

MFGGLLGEETKRHFERLMKTKNDRLGASHRNERSIRDGDMVDAPFLNFAIPVPRRHQTVMPAIGILHNCCDSLGIYSAITTRMLYSSIACSEFDELRRDSVPRCYPRITNAQAFLSPMMMRVANSIIFQEYDEMECAAHRNAYYSTMNSFISMRTSDAFKQLTVFISRFSKLLIASFRDVNKLDDHTVKKRARIDAPSYDKLHGTLELFQKMILMHATYFVTSVLLGDHAERAERLLRVAFDTPHFSDIVTRHFRQRATVFLVPRRHGKTWFLVPLIALAMSSFEGIRIGYTSHIRKAIEPVFEDIGDRLRRWFGAHRVDHVKGETITFSFPSGLKSTVTFASSHNTNSIRGQDFNLLFVDEANFIRPDAVQTIIGFLNQATCKIIFVSSTNSGKASTSFLYGLKGSADDLLNVVTYICDEHMKHVTDYTNATSCSCYVLNKPVFITMDGAMRRTAEMFLPDSFMQEIIGGGVVDRTICQGDRSIFTASAIDRFLIYRPSTVNNQDPFSQDLYVYVDPAFTANTKASGTGVAVIGKYGTDYIVFGLEHYFLRALTGESSDSIGYCVAQCLIQICAIHRKRFGVIKIAIEGNSNQDSAVAIATRIAIEMISYMKAAVAPTPHNVSFYHSKSNGTDVEYPYFLLQRQKTTAFDFFIAQFNSGRVLASQDLVSTTVSLTTDPVEYLTKQLTNISEVVTGPTCTRTFSGKKGGNDDTVVALTMAVYISAHIPDMAFAPIRV

TRM3

Tripartite terminase subunit 3

735 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

80.923 kDa

MFGQQLASDVQQYLERLEKQRQLKVGADEASAGLTMGGDALRVPFLDFATATPKRHQTVVPGVGTLHDCCEHSPLFSAVARRLLFNSLVPAQLKGRDFGGDHTAKLEFLAPELVRAVARLRFKECAPADVVPQRNAYYSVLNTFQALHRSEAFRQLVHFVRDFAQLLKTSFRASSLTETTGPPKKRAKVDVATHGRTYGTLELFQKMILMHATYFLAAVLLGDHAEQVNTFLRLVFEIPLFSDAAVRHFRQRATVFLVPRRHGKTWFLVPLIALSLASFRGIKIGYTAHIRKATEPVFEEIDACLRGWFGSARVDHVKGETISFSFPDGSRSTIVFASSHNTNGIRGQDFNLLFVDEANFIRPDAVQTIMGFLNQANCKIIFVSSTNTGKASTSFLYNLRGAADELLNVVTYICDDHMPRVVTHTNATACSCYILNKPVFITMDGAVRRTADLFLADSFMQEIIGGQARETGDDRPVLTKSAGERFLLYRPSTTTNSGLMAPDLYVYVDPAFTANTRASGTGVAVVGRYRDDYIIFALEHFFLRALTGSAPADIARCVVHSLTQVLALHPGAFRGVRVAVEGNSSQDSAVAIATHVHTEMHRLLASEGADAGSGPELLFYHCEPPGSAVLYPFFLLNKQKTPAFEHFIKKFNSGGVMASQEIVSATVRLQTDPVEYLLEQLNNLTETVSPNTDVRTYSGKRNGASDDLMVAVIMAIYLAAQAGPPHTFAPITRVS

TRM3

Tripartite terminase subunit 3

734 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

80.973 kDa

MFGQQLASDVQQYLERLEKQRQQKVGVDEASAGLTLGGDALRVPFLDFATATPKRHQTVVPGVGTLHDCCEHSPLFSAVARRLLFNSLVPAQLRGRDFGGDHTAKLEFLAPELVRAVARLRFRECAPEDAVPQRNAYYSVLNTFQALHRSEAFRQLVHFVRDFAQLLKTSFRASSLAETTGPPKKRAKVDVATHGQTYGTLELFQKMILMHATYFLAAVLLGDHAEQVNTFLRLVFEIPLFSDTAVRHFRQRATVFLVPRRHGKTWFLVPLIALSLASFRGIKIGYTAHIRKATEPVFDEIDACLRGWFGSSRVDHVKGETISFSFPDGSRSTIVFASSHNTNGIRGQDFNLLFVDEANFIRPDAVQTIMGFLNQANCKIIFVSSTNTGKASTSFLYNLRGAADELLNVVTYICDDHMPRVVTHTNATACSCYILNKPVFITMDGAVRRTADLFLPDSFMQEIIGGQARETGDDRPVLTKSAGERFLLYRPSTTTNSGLMAPELYVYVDPAFTANTRASGTGIAVVGRYRDDFIIFALEHFFLRALTGSAPADIARCVVHSLAQVLALHPGAFRSVRVAVEGNSSQDSAVAIATHVHTEMHRILASAGANGPGPELLFYHCEPPGGAVLYPFFLLNKQKTPAFEYFIKKFNSGGVMASQELVSVTVRLQTDPVEYLSEQLNNLIETVSPNTDVRMYSGKRNGAADDLMVAVIMAIYLAAPTGIPPAFFPITRTS

TRM3

Tripartite terminase subunit 3

734 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

81.078 kDa

MFGRVLGRETVQYFEALRREVQARRGAKNRAAEAQNGGEDDAKTAFLNFAIPTPQRHQTVVPGVGTLHDCCETAQIFASVARRLLFRSLSKWQSGEARERLDPASVEAYVDPKVRQALKTISFVEYSDDEARSCRNAYYSIMNTFDALRSSDAFHQVASFVARFSRLVDTSFNGADLDGDGQQASKRARVDVPTYGKQRGTLELFQKMILMHATYFIAAVILGDHADRIGAFLKMVFNTPEFSDATIRHFRQRATVFLVPRRHGKTWFLVPLIALALATFKGIKIGYTAHIRKATEPVFDEIGARLRQWFGNSPVDHVKGENISFSFPDGSKSTIVFASSHNTNGIRGQDFNLLFVDEANFIRPEAVQTIIGFLNQTNCKIIFVSSTNTGKASTSFLYNLKGAADDLLNVVTYICDEHMERVKAHTNATACSCYILNKPVFITMDGAMRNTAELFLPDSFMQEIIGGGNVSGAHRDEPVFTKTAQDRFLLYRPSTVANQDIMSSDLYVYVDPAFTTNAMASGTGVAVVGRYRSNWVVFGMEHFFLSALTGSSAELIARCVAQCLAQVFAIHKRPFDSVRVAVEGNSSQDAAVAIATNIQLELNTLRRADVVPMPGAVLFYHCTPHGSSVAYPFFLLQKQKTGAFDHFIKAFNSGSVLASQELVSNTVRLQTDPVEYLLTQMKNLTEVVTGTSETRVFTGKRNGASDDMLVALVMAVYLSSLPPTSDAFSSLPAQ

TRM3

Tripartite terminase subunit 3

734 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

81.078 kDa

MFGRVLGRETVQYFEALRREVQARRGAKNRAAEAQNGGEDDAKTAFLNFAIPTPQRHQTVVPGVGTLHDCCETAQIFASVARRLLFRSLSKWQSGEARERLDPASVEAYVDPKVRQALKTISFVEYSDDEARSCRNAYYSIMNTFDALRSSDAFHQVASFVARFSRLVDTSFNGADLDGDGQQASKRARVDVPTYGKQRGTLELFQKMILMHATYFIAAVILGDHADRIGAFLKMVFNTPEFSDATIRHFRQRATVFLVPRRHGKTWFLVPLIALALATFKGIKIGYTAHIRKATEPVFDEIGARLRQWFGNSPVDHVKGENISFSFPDGSKSTIVFASSHNTNGIRGQDFNLLFVDEANFIRPEAVQTIIGFLNQTNCKIIFVSSTNTGKASTSFLYNLKGAADDLLNVVTYICDEHMERVKAHTNATACSCYILNKPVFITMDGAMRNTAELFLPDSFMQEIIGGGNVSGAHRDEPVFTKTAQDRFLLYRPSTVANQDIMSSDLYVYVDPAFTTNAMASGTGVAVVGRYRSNWVVFGMEHFFLSALTGSSAELIARCVAQCLAQVFAIHKRPFDSVRVAVEGNSSQDAAVAIATNIQLELNTLRRADVVPMPGAVLFYHCTPHGSSVAYPFFLLQKQKTGAFDHFIKAFNSGSVLASQELVSNTVRLQTDPVEYLLTQMKNLTEVVTGTSETRVFTGKRNGASDDMLVALVMAVYLSSLPPTSDAFSSLPAQ

TRM3

Tripartite terminase subunit 3

690 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

76.694 kDa

MLYASQRGRLTENLRNALQQDSTTQGCLGAETPSIMYTGAKSDRWAHPLVGTIHASNLYCPMLRAYCRHYGPRPVFVASDESLPMFGASPALHTPVQVQMCLLPELRDTLQRLLPPPNLEDSEALTEFKTSVSSARAILEDPNFLEMREFVTSLASFLSGQYKHKPARLEAFQKQVVLHSFYFLISIKSLEITDTMFDIFQSAFGLEEMTLEKLHIFKQKASVFLIPRRHGKTWIVVAIISLILSNLSNVQIGYVAHQKHVASAVFTEIIDTLTKSFDSKRVEVNKETSTITFRHSGKISSTVMCATCFNKNSIRGQTFHLLFVDEANFIKKEALPAILGFMLQKDAKIIFISSVNSADQATSFLYKLKDAQERLLNVVSYVCQEHRQDFDMQDSMVSCPCFRLHIPSYITMDSNIRATTNLFLDGAFSTELMGDTSSLSQGSLSRTVRDDAINQLELCRVDTLNPRVAGRLASSLYVYVDPAYTNNTSASGTGIAAVTHDRADPNRVIVLGLEHFFLKDLTGDAALQIATCVVALVSSIVTLHPHLEEVKVAVEGNSSQDSAVAIASIIGESCPLPCAFVHTKDKTSSLQWPMYLLTNEKSKAFERLIYAVNTASLSASQVTVSNTIQLSFDPVLYLISQIRAIKPIPLRDGTYTYTGKQRNLSDDVLVALVMAHFLATTQKHTFKKVH

TRM3

Tripartite terminase subunit 3

690 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

76.694 kDa

MLYASQRGRLTENLRNALQQDSTTQGCLGAETPSIMYTGAKSDRWAHPLVGTIHASNLYCPMLRAYCRHYGPRPVFVASDESLPMFGASPALHTPVQVQMCLLPELRDTLQRLLPPPNLEDSEALTEFKTSVSSARAILEDPNFLEMREFVTSLASFLSGQYKHKPARLEAFQKQVVLHSFYFLISIKSLEITDTMFDIFQSAFGLEEMTLEKLHIFKQKASVFLIPRRHGKTWIVVAIISLILSNLSNVQIGYVAHQKHVASAVFTEIIDTLTKSFDSKRVEVNKETSTITFRHSGKISSTVMCATCFNKNSIRGQTFHLLFVDEANFIKKEALPAILGFMLQKDAKIIFISSVNSADQATSFLYKLKDAQERLLNVVSYVCQEHRQDFDMQDSMVSCPCFRLHIPSYITMDSNIRATTNLFLDGAFSTELMGDTSSLSQGSLSRTVRDDAINQLELCRVDTLNPRVAGRLASSLYVYVDPAYTNNTSASGTGIAAVTHDRADPNRVIVLGLEHFFLKDLTGDAALQIATCVVALVSSIVTLHPHLEEVKVAVEGNSSQDSAVAIASIIGESCPLPCAFVHTKDKTSSLQWPMYLLTNEKSKAFERLIYAVNTASLSASQVTVSNTIQLSFDPVLYLISQIRAIKPIPLRDGTYTYTGKQRNLSDDVLVALVMAHFLATTQKHTFKKVH

TRM3

Tripartite terminase subunit 3

690 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

76.704 kDa

MLYASQRGRLTENLRNALQQDSTTQGCLGAETPSIMYTGAKPDRWAHPLVGTIHASNLYCPMLRAYCRHYGPRPVFVASDESLPMFGASPALHTPVQVQMCLLPELRDTLQRLLPPPNLEDSEALTEFKTSVSSARAILEDPNFLEMREFVTSLASFLSGQYKHKPARLEAFQKQVVLHSFYFLISIKSLEITDTMFDIFQSAFGLEEMTLEKLHIFKQKASVFLIPRRHGKTWIVVAIISLILSNLSNVQIGYVAHQKHVASAVFTEIIDTLTKSFDSKRVEVNKETSTITFRHSGKISSTVMCATCFNKNSIRGQTFHLLFVDEANFIKKEALPAILGFMLQKDAKIIFISSVNSADQATSFLYKLKDAQERLLNVVSYVCQEHRQDFDMQDSMVSCPCFRLHIPSYITMDSNIRATTNLFLDGAFSTELMGDTSSLSQGSLSRTVRDDAINQLELCRVDTLNPRVAGRLASSLYVYVDPAYTNNTSASGTGIAAVTHDRADPNRVIVLGLEHFFLKDLTGDAALQIATCVVALVSSIVTLHPHLEEVKVAVEGNSSQDSAVAIASIIGESCPLPCAFVHTKDKTSSLQWPMYLLTNEKSKAFERLIYAVNTASLSASQVTVSNTIQLSFDPVLYLISQIRAIKPIPLRDGTYTYTGKQRNLSDDVLVALVMAHFLATTQKHTFKKVH

TRM3

Tripartite terminase subunit 3

687 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

76.529 kDa

MLLSRHRERLAANLQETAKDAGERWELSAPTFTRHCPKTARMAHPFIGVVHRINSYSSVLETYCTRHHPATPTSANPDVGTPRPSEDNVPAKPRLLESLSTYLQMRCVREDAHVSTADQLVEYQAARKTHDSLHACSVYRELQAFLVNLSSFLNGCYVPGVHWLEPFQQQLVMHTFFFLVSIKAPQKTHQLFGLFKQYFGLFETPNSVLQTFKQKASVFLIPRRHGKTWIVVAIISMLLASVENINIGYVAHQKHVANSVFAEIIKTLCRWFPPKNLNIKKENGTIIYTRPGGRSSSLMCATCFNKNSIRGQTFNLLYVDEANFIKKDALPAILGFMLQKDAKLIFISSVNSSDRSTSFLLNLRNAQEKMLNVVSYVCADHREDFHLQDALVSCPCYRLHIPTYITIDESIKTTTNLFMEGAFDTELMGEGAASSNATLYRVVGDAALTQFDMCRVDTTAQQVQKCLGKQLFVYIDPAYTNNTEASGTGVGAVVTSTQTPTRSLILGMEHFFLRDLTGAAAYEIASCACTMIKAIAVLHPTIERVNAAVEGNSSQDSGVAIATVLNEICPLPIHFLHYTDKSSALQWPIYMLGGEKSSAFETFIYALNSGTLSASQTVVSNTIKISFDPVTYLVEQVRAIKCVPLRDGGQSYSAKQKHMSDDLLVAVVMAHFMATDDRHMYKPISPQ

TRM3

Tripartite terminase subunit 3

686 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

76.86 kDa

MFYVKVMPALQKACEELQNQWSAKSGKWPVPETPLVAVETRRSERWPHPYLGLLPGVAAYSSTLEDYCHLYNPYIDALTRCDLGQTHRRVATQPVLSDQLCQQLKKLFSCPRNTSVKAKLEFEAAVRTHQALDNSQVFLELKTFVLNLSAFLNKRYSDRSSHIELFQKQLIMHTFFFLVSIKAPELCEKFCNIFKLYFNIDTMDQATLDIFKQKASVFLIPRRHGKTWIVVAIISILLASVQDLRIGYVAHQKHVANAVFTEVINTLHTFFPGKYMDVKKENGTIIFGLPNKKPSTLLCATCFNKNSIRGQTFQLLFVDEANFIKKDALPTILGFMLQKDAKIIFISSSNSSDQSTSFLYNLKGASERMLNVVSYVCSNHKEDFSMQDGLISCPCYSLHVPSYISIDEQIKTTTNLFLDGVFDTELMGDSSCGTLSTFQIISESALSQFELCRIDTASPQVQAHLNSTVHMYIDPAFTNNLDASGTGISVIGRLGAKTKVILGCEHFFLQKLTGTAALQIASCATSLLRSVVIIHPMIKCAQITIEGNSSQDSAVAIANFIDECAPIPVTFYHQSDKTKGVLCPLYLLGQEKAVAFESFIYAMNLGLCKASQLIVSHTIKLSFDPVTYLLEQVRAIKCQSLRDGSHTYHAKQKNLSDDLLVSVVMSLYLSSANTLPFKPLHIERFF

TRM3

Tripartite terminase subunit 3

686 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

76.458 kDa

MILSGKKRMLLDNYKNARAPGGDDERDWVFDRPAIVTRRDKSDRMAHPYIGIIPRTNIYSAVLDSYCKSLNPVYKERIPPVLGTGRDVPVTPANVTGELARAARALCGDLASGDPEALVEFASAVQTQRTSRGCPVFRELSEFLVNLASFLNRCYSVKSDTIEPFQKQLILHTFYFLISIKAPHAANTLFEVFKEYFGLFDMGREALQTFKQKSTVYLIPRRHGKTWIVVAIISMLLTSVENIHVGYVAHQKHVANSVFAEIINTIYRWFPAKNVYIKKENGTIMYTNENRRPSTLMCATCFNKNSIRGQTFNLLYVDEANFIKKDSLPSILGFMLQKDAKIIFISSVNSSDQTTSFLYNLKNAKEKMLNVVNYVCPQHREDFSLQESVVSCPCYRLHIPTYIAIDENIKDTTNLFMEGAFTTELMGDGAAATTQTNMHKVVGEPALVQFDLCRVDTGSPEAQRGLNPTLFLYVDPAYTNNTEASGTGMGAVVSMKNSDRCVVVGVEHFFLKELTGASSLQIASCAAALIRSLATLHPFVREAHVAIEGNSSQDSAVAIATLLHERSPLPVKFLHHADKATGVQWPMYILGAEKARAFETFIYALNSNTLSCGQAIVSNTIKLSFDPVAYLIEQIRAIKCYPLKDGTVSYCAKHKGGSDDTLVAVVMAHYFATSDRHVFKNHMKQI

TRM3

Tripartite terminase subunit 3

683 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

77.05 kDa

MLLLKAKKAIIENLSEVSSTQAETDWDMSTPTIITNTSKSERTAYSKIGVIPSVNLYSSTLTSFCKLYHPLTLNQTQPQTGTLRLLPHEKPLILQDLSNYVKLLTSQNVCHDTEANTEYNAAVQTQKTSMECPTYLELRQFVINLSSFLNGCYVKRSTHIEPFQLQLILHTFYFLISIKSPESTNRLFDIFKEYFGLREMDPDMLQIFKQKASIFLIPRRHGKTWIVVAIISMLLTSVENIHVGYVAHQKHVANSVFTEIINTLQKWFPSRYIDIKKENGTIIYKSPDKKPSTLMCATCFNKNSIRGQTFNLLYIDEANFIKKDSLPAILGFMLQKDAKLIFISSVNSGDRATSFLFNLKNASEKMLNIVNYICPDHKDDFSLQDSLISCPCYKLYIPTYITIDETIKNTTNLFLDGAFTTELMGDMSGISKSNMHKVISEMAITQFDLCRADTTKPEITQCLNSTMYIYIDPAYTNNSEASGTGIGAILTFKNNSSKCIIVGMEHYFLKDLTGTATYQIASCACSLIRASLVLYPHIQCVHVAVEGNSSQDSAVAISTLINECSPIKVYFIHYKDKTTTMQWPIYMLGAEKSIAFESFIYAINSGTISASQSIISNTIKLSFDPISYLIEQIRSIRCYPLRDGSHTYCAKKRTVSDDVLVAVVMAYFFATSNKHIFKPLNST

TRM3

Tripartite terminase subunit 3

674 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

77.079 kDa

MLRGDSAAKIQERYAELQKRKSHPTSCISTAFTNVATLCRKRYQMMHPELGLAHSCNEAFLPLMAFCGRHRDYNSPEESQRELLFHERLKSALDKLTFRPCSEEQRASYQKLDALTELYRDPQFQQINNFMTDFKKWLDGGFSTAVEGDAKAIRLEPFQKNLLIHVIFFIAVTKIPVLANRVLQYLIHAFQIDFLSQTSIDIFKQKATVFLVPRRHGKTWFIIPIISFLLKHMIGISIGYVAHQKHVSQFVLKEVEFRCRHTFARDYVVENKDNVISIDHRGAKSTALFASCYNTNSIRGQNFHLLLVDEAHFIKKEAFNTILGFLAQNTTKIIFISSTNTTSDSTCFLTRLNNAPFDMLNVVSYVCEEHLHSFTEKGDATACPCYRLHKPTFISLNSQVRKTANMFMPGAFMDEIIGGTNKISQNTVLITDQSREEFDILRYSTLNTNAYDYFGKTLYVYLDPAFTTNRKASGTGVAAVGAYRHQFLIYGLEHFFLRDLSESSEVAIAECAAHMIISVLSLHPYLDELRIAVEGNTNQAAAVRIACLIRQSVQSSTLIRVLFYHTPDQNHIEQPFYLMGRDKALAVEQFISRFNSGYIKASQELVSYTIKLSHDPIEYLLEQIQNLHRVTLAEGTTARYSAKRQNRISDDLIIAVIMATYLCDDIHAIRFRVS

TRM3

Tripartite terminase subunit 3

674 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

77.034 kDa

MLRGDSAAKIQERYAELQKRKSHPTSCISTAFTNVAALCRKRYQMMHPELGLAHSCNEAFLPLMAFCGRHRDYNSPEESQRELLFHERLKSALDELTFRPCSEEQRASYQKLDALTELYRDPQFQQINNFMTDFKKWLDGGFSTAVEGDAKAIRLEPFQKNLLIHVIFFIAVTKIPVLANRVLQYLIHAFQIDFLSQTSIDIFKQKATVFLVPRRHGKTWFIIPIISFLLKHMIGISIGYVAHQKHVSQFVLKEVEFRCRHTFARDYVVENKDNVISIDHRGAKSTALFASCYNTNSIRGQNFHLLLVDEAHFIKKEAFNTILGFLAQNTTKIIFISSTNTTSDATCFLTRLNNAPFDMLNVVSYVCEEHLHSFTEKGDATACPCYRLHKPTFISLNSQVRKTANMFMPGAFMDEIIGGTNKISQNTVLITDQSREEFDILRYSTLNTNAYDYFGKTLYVYLDPAFTTNRKASGTGVAAVGAYRHQFLIYGLEHFFLRDLSESSEVAIAECAAHMIISVLSLHPYLDELRIAVEGNTNQAAAVRIACLIRQSVQSSTLIRVLFYHTPDQNHIEQPFYLMGRDKALAVEQFISRFNSGYIKASQELVSYTIKLSHDPIEYLLEQIQNLHRVTLAEGTTARYSAKRQNRISDDLIIAVIMATYLCDDIHAIRFRVS

TRM3

Tripartite terminase subunit 3

667 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

76.36 kDa

MLRTCDITHIKNNYEAIIWKGERDCSTISTKYPNSAIFYKKRFIMLTPELGFAHSYNQQVKPLYTFCEKQRHLKNRKPLTILPSLSHKLQEMKFLPASDKSFESQYTEFLESFKILYREPLFLQIDGFIKDFRKWIKGEFNDFGDTRKIQLEPFQKNILIHVIFFIAVTKLPALANRVINYLTHVFDIEFVNESTLNTLKQKTNVFLVPRRHGKTWFIVPIISFLLKNIEGISIGYVAHQKHVSHFVMKEVEFKCRRMFPEKTITCLDNVITIDHQNIKSTALFASCYNTHQSIRGQSFNLLIVDESHFIKKDAFSTILGFLPQASTKILFISSTNSGNHSTSFLMKLNNSPFEMLSVVSYVCEDHAHMLNERGNATACSCYRLHKPKFISINAEVKKTANLFLEGAFIHEIMGGATCNVINDVLITEQGQTEFEFFRYSTINKNLIPFLGKDLYVYLDPAYTGNRRASGTGIAAIGTYLDQYIVYGMEHYFLESLMTSSDTAIAECAAHMILSILDLHPFFTEVKIIIEGNSNQASAVKIACIIKENITANKSIQVTFFHTPDQNQIAQPFYLLGKEKKLAVEFFISNFNSGNIKASQELISFTIKITYDPVEYALEQIRNIHQISVNNYITYSAKKQACSDDLIIAIIMAIYVCSGNSSASFREI

TRM3

Tripartite terminase subunit 3

666 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

76.264 kDa

MLRTCDITHIKNNYEAIIWKGERNCSTISTKYPNSAIFYKKRFIMLTPELGFAHSYNQQVKPLYTFCEKQRHLKNRKPLTILPSLTRKLQEMKFLPASDKSFESQYTEFLESFKILYREPLFLQIDGFIKDFRKWIKGEFNDFGDTRKIQLEPFQKNILIHVIFFIAVTKLPALANRVINYLTHVFDIEFVNESTLNTLKQKTNVFLVPRRHGKTWFIVPIISFLLKNIEGISIGYVAHQKHVSHFVMKEVEFKCRRMFPEKTITCLDNVITIDHQNIKSTALFASCYNTHSIRGQSFNLLIVDESHFIKKDAFSTILGFLPQASTKILFISSTNSGNHSTSFLMKLNNSPFEMLSVVSYVCEDHAHMLNERGNATACSCYRLHKPKFISINAEVKKTANLFLEGAFIHEIMGGATCNVINDVLITEQGQTEFEFFRYSTINKNLIPFLGKDLYVYLDPAYTGNRRASGTGIAAIGTYLDQYIVYGMEHYFLESLMTSSDTAIAECAAHMILSILDLHPFFTEVKIIIEGNSNQASAVKIACIIKENITANKSIQVTFFHTPDQNQIAQPFYLLGKEKKLAVEFFISNFNSGNIKASQELISFTIKITYDPVEYALEQIRNIHQISVNNYITYSAKKQACSDDLIIAIIMAIYVCSGNSSASFREI

TRM3

Tripartite terminase subunit 3

663 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

76.412 kDa

MLRSCDIDAIQKAYQSIIWKHEQDVKISSTFPNSAIFCQKRFIILTPELGFTHAYCRHVKPLYLFCDRQRHVKSKIAICDPLNCALSKLKFTAIIEKNTEVQYQKHLELQTSFYRNPMFLQIEKFIQDFQRWICGDFENTNKKERIKLEPFQKSILIHIIFFISVTKLPTLANHVLDYLKYKFDIEFINESSVNILKQKASVFLVPRRHGKTWFMIPVICFLLKNLEGISIGYVAHQKHVSHFVMKDVEFKCRRFFPQKNITCQDNVITIEHETIKSTALFASCYNTHSIRGQSFNLLIVDESHFIKKDAFSTILGFLPQSSTKIIFISSTNSGNHSTSFLTKLSNSPFEMLTVVSYVCEDHVHILNDRGNATTCACYRLHKPKFISINADVKKTADLFLEGAFKHEIMGGSLCNVVNDTLITEQGLIEFDLFRYSTISKQIIPFLGKELYIYIDPAYTINRRASGTGVAAIGTYGDQYIIYGMEHYFLESLLSNSDASIAECASHMILAVLELHPFFTELKIIIEGNSNQSSAVKIACILKQTISVIRYKHITFFHTLDQSQIAQPFYLLGREKRLAVEYFISNFNSGYIKASQELISFTIKITYDPIEYVIEQIKNLHQININEHVTYNAKKQTCSDDLLISIIMAIYMCHEGKQTSFKEI

TRM3

Tripartite terminase subunit 3

660 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

75.392 kDa

MLCKRTLSEISSLYTASKKKKTVIDTLSYTYPDVLLSCNERYQITHPELGIVHASNLYCSSLESFCLQYRDYGNDLSIRSCEKLVFSDALITGLSRIKFTPWPECRTRYETTVSELRRLHDMDNFTEASGFLEDLKRWLCSQNVFLEPFQKNCILHVICFLVATRTPHHYHYIFEYIKRLFNIENINTSVLDTFKHKTTVFLVPRRHGKTWILTPIITFLIKNFSNISVGYVAHQKHVSQHVMKEVEILCRREIPYVVENKDNVISVIRTNSRSCALFASCFNTNSIRGQSFNILLVDESNFIKKEALHAIIGFLAQSTAKIIFISSCNTSTQSTSFLAHVKKTPTQILNVISYVCEEHLYSFGERSEAITCPCYRLHKPTFISLNLNIKKTANAFLKDSFNEEILGTTNTSFLANPILTDSSVNEFDMIRYSTVNKQLQEHLADTLFVYVDPAFTTNRRASGTGVAGVGRYNNQFIVYGIEHFYLKSLADTSEDSIGECVAFMISGIIKIHPFFTMVRVLIEGNSSQAASVKIAYCIKAHLSDSACILQFYQTLDQNGFEQPFFLLKKNKRAAVEHFVSKFNSNLIKASQEIISHTIKLNFDPIEYLLLQIKNISQIVTTESVEYTTRKTKDSSDDALVAVIMAIYFCNDQEVALYKCI

TRM3

Tripartite terminase subunit 3

506 amino acids

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.

Belongs to the herpesviridae TRM3 protein family.

55.025 kDa

MHRSDSTMWLKYGLSPPTRSPNAALCAAAATKCASMTRPSCVLDSLTLYSPAWPCLCRYAIFPCRAWAIYVRAGNFILTKFSRFSFCFCVWSPRPPIAAAANHPATSTIVARSQGLRGQDFNFLFVDEANFIKPGAMHTIMGFLNQTNCKLFFVSSTNTGQSSTSLLYNLKGSSNSLLNVVTYICDDHLPEVQQRQNVTTCSCYVLQKPVYVTMDHSVRNTAELFVKDSFMNEIAGGQVGNTLSARSVIASRAMDQFLVYRPSTSNSPNVHNLSRVLTAYIDPAFTANRSASGTGIALVTELNGATVLLGMEHFYLEALTGEAAAEIAQCANLCVAYTCLLHPGVFREVRVAVEGNSSQDSATAIALRLADLLAPLQKRLGFSLVFAHTRQHGSSVAHPFYLLNKQKSRAFDLFISRFNSGNIMASQELVSNTVLLGNDPCEYLVEQIKNLEIVITSGDANRVYSGKQGGKLADDVLVAVVMAAYLSFEGAPPAGYHTVSGAVCRR