TRM13

Gene

trm13

Protein

tRNA:m(4)X modification enzyme TRM13 homolog

Organism

Dictyostelium discoideum

Length

525 amino acids

Function

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

Similarity

Belongs to the methyltransferase TRM13 family.

Mass

61.425 kDa

Sequence

MGEINNNKEINEKDDEINNKRLKYEGFIKKEKKKKQKIDHSIPLKEKPTQEDIDSHSECLFWIVNKKKHRAEFCKYKRAKDSILCNHHKPIDQISSEPQPQLTDYNGDDVTENNNNSTTTTTATTQDDNSKPKERKRIHCPLNPTHIIYECKLQKHLKACPNAKVGQKNAHIELSKKEPYYKENINDLNENVKLTLEPIILSQVSTENLINISIKLDQFFEKFFKNEIQSLNQTHKSFDKIFNSDQQLKHIQQESSIINLLENSNLYNSDNVYLEFGAGSGKLSNHIFMSHEKKSGHILIDRMKFRSLKKVDRLIKNEKGCHHFSRLLIDIRHLNLSNLSILEEKPFVITSKHLCGCATDFTLDSIFNLLNNSNEKVNNNFKGIGIATCCHHICNFNTYSNQSYLKDQLNITPLEFQLICSISSWATIDENKCNNDDDDNEVEEDDELIKKDKKEKKEFENQLKIEFNKQDVFSIKRKEELGYKAKRLIDYGRYLFIKEKLNLPNTKFWIYTNQSKENLFLVSNK

Protein

tRNA:m(4)X modification enzyme TRM13 homolog: trm13

Gene

TRM13

Protein

tRNA:m(4)X modification enzyme TRM13

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

476 amino acids

Function

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

Similarity

Belongs to the methyltransferase TRM13 family.

Mass

54.095 kDa

Sequence

MLQDNNGPAVKRAKPSERLQCEYFMEKKKRRCGMTRSSQNLYCSEHLNLMKKAANSQVHNKNGSEAEKERERVPCPLDPNHTVWADQLKKHLKKCNKTKLSHLNDDKPYYEPGYNGENGLLSSSVKIDITAEHLVQSIELLYKVFEGESMDELPLRQLNNKLMSLKRFPQLPSNTKHAVQQSSLIENLVDAGAFERPESLNFIEFGCGRAEFSRYVSLYLLTQLTSLPAEHSGSNSNEFVLIDRATNRMKFDKKIKDDFSEIKSNSPSKPISCPSIKRIKIDIRDLKMDPILKSTPGDDIQYVCISKHLCGVATDLTLRCIGNSSILHGDDNNGCNPKLKAICIAMCCRHVCDYGDYVNRSYVTSLVEKYRAHGSILTYETFFRVLTKLCSWGTCGRKPGTAITDIVNVVESFEGAEPYTITIKERENIGLMARRVIDEGRLVYVKEKFTEFNAELIRYVESDVSLENVAMLVYKK

Protein

tRNA:m(4)X modification enzyme TRM13: TRM13

Gene

TRM13

Protein

tRNA:m(4)X modification enzyme TRM13

Organism

Yarrowia lipolytica (strain CLIB 122 / E 150)

Length

464 amino acids

Function

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

Similarity

Belongs to the methyltransferase TRM13 family.

Mass

52.624 kDa

Sequence

MTTETGIPEVVKASSETMSADGKPEKPNPSMFPKRQKRDTPKEYSYLRCEYKLPHKNHRQCHMQRKAEEKFCAQHVLLQKDSYAGRERVVCPVDPGHTVWADELQQHMYKCNKVKERMQKEREGWHRDDMNISNPEAKPCVGKKSDITVDYAKWIPVVEAAFKDVEEVPVEILNHEKGLAKRMTEVQNKKHALQQASLIAHMEKTGLLKSSSRILEFGAGRAELSRYINYAICAERQQDDKTAANYLFIDRAMPRMKMDGKLVKDTKDDFPEQPLPLIKRLKMDIKDLMLDGVPVEGPYDANLIVSKHLCGCATDLTLQCLLNSAVFTKEARPAALVIALCCRQICNVQMFPKAGIEWLQERGFDDDGFAALTRMTSWVLCGERPKKEPVEGEQTEAADNETPAPVGHPSGLPAEARKVIGLKCRRLLDQGRLHALRKEGLDARLVQYTEMDISPENVCLIVNK

Protein

tRNA:m(4)X modification enzyme TRM13: TRM13

Gene

TRM13

Protein

tRNA:m(4)X modification enzyme TRM13

Organism

Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)

Length

457 amino acids

Function

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

Similarity

Belongs to the methyltransferase TRM13 family.

Mass

52.466 kDa

Sequence

MANIDKEVLASQPDEISKDQKRRKLNKHEKKERTHLQCEYFIAKKNRRCCMQRKADRKYCSEHLVDNNEPDKGERVPCPLDNNHSVWSKNLTNHLKKCNAKPKENEEIWYEKDLNTKLGVDITEDSFKNDGNDNDNEDDDLNEKELYEKYIPILRNIKDHFEPLGFSISKHSGLKNRLSEVSNQKHAIQQSSLIGNMKKRGLLDINKFYLEFGCGKGELSRFVNLSVLEDLQVKDLAGKSKYGYGFIDRGVNRMKMDSKIVKDAKENTIEVNITTKRSKIDIKDLHVDKFLKDIDPEHVVVISKHLCGAATDLTFKSLLNSSLLQGNSDKFGGLLIAMCCRHVCAYDQLLPESRAFLQSKGFRSLSSFNILKKIVSWAVCGKRDGTNEESTGEHISGLTFKEREELGLVARRLIDESRVFAMNLLVNPLGFHTEMFWYVEKEITLENVCLCIIPDSN

Protein

tRNA:m(4)X modification enzyme TRM13: TRM13

Gene

TRM13

Protein

tRNA:m(4)X modification enzyme TRM13

Organism

Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)

Length

442 amino acids

Function

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

Similarity

Belongs to the methyltransferase TRM13 family.

Mass

48.34 kDa

Sequence

MEASSLVAERPTGGEQDPGHARCAFYLPRKRRSCGMAPKAGARFCAEHQPGDSGTAARVPCPLDPRHTVAKAQLRSHLARCNRTKQDQALRAEREHMPWYEAGVNSAARPAAAAADEATLQAAVMRAIPVLAQIAEAEFRAPLRVAVLSNAQVEHVRFPQLPSNRKHALQQSSLIQHLREAGLWVAPERPVAYVEFGCGRGELSRYINQAAVLEQLERGGPAAPPAFVLVDRACPRMKFDSKFAEDVAELHARFCPSVPPDERPAPAVTRKKIDIRDLRLAALLSPGLEHIAVSKHLCGVATDLTLRCLAAGPRASLCGALIAMCCRHACNPAEYANPAYVEALLARHAPDMSYDLFFLALMKMASWAVSGRRPGVPDTEVGGHFSGLAIAERERLGHLARRLVDEGRRQYFADLGYDAELLVYCERDTSREDIALLVRRPA

Protein

tRNA:m(4)X modification enzyme TRM13: TRM13

Gene

TRM13

Protein

tRNA:m(4)X modification enzyme TRM13

Organism

Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)

Length

434 amino acids

Function

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

Similarity

Belongs to the methyltransferase TRM13 family.

Mass

49.673 kDa

Sequence

MMAVTVSGNTGQSTAERLQCEFFLVKKKRQCGMTRRAGSQFCSEHSTDSDRVPCPLDPSHTVCLSKMRVHMRKCNKFRHDVSYQAKQREIPWFKEGLNSISNGKSDSKPADETLVKSVSLIQKIFQNEFGDEPPLPLIEKQNELLERTERYKTLVNRKHARQQSSLIQHLKESKLWPSLESCAVNKTLEYIELGCGRAEFSRYVNIATNLDQKEHSHEKPEYKAVAPSFTLIDRASQRLRFDNKFSSDIGTEVQIRREKIDIKDLRLDAVLHDASQYVAISKHLCGVATDLSLRCLLNSDKCKANLRGILIAMCCRHVCQSSEYVNQEYIKGLLKRQTDGSMAYSEFFQCLKKFCSYCTCGLRPDMDPNSGSEDHITKLTHNERQRIGHMARRIIDEGRAQFLQSKGFETVLFKYTDSAVTLEDTALLALRKHD

Protein

tRNA:m(4)X modification enzyme TRM13: TRM13

Gene

TRM13

Protein

tRNA:m(4)X modification enzyme TRM13

Organism

Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)

Length

430 amino acids

Function

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

Similarity

Belongs to the methyltransferase TRM13 family.

Mass

50.213 kDa

Sequence

MQPESKKQRLQCEFYMEKKKRRCGMSRNLSSKYCSEHQILNENTKRIPCPLDPNHTVWESDLDSHLKKCNKLKLIHQHDNKPYFLKDCNAITTEDSNTTVITKDSLQNWIMKTIPVLKNFFKDDEKNYLSNVPLDIRKNHTMEDKRFPQLNENDNIGKKYHAIQQSSLIQNMIDRNILQFKENSLANFIEFGCGRAELSRYVNQVVIKNSEEKIYNPHFILIDRSTNRMKFDTKMKKDALEFNQNLNPPTITRIRIDIKDLKIDPLLQKDSKYIAISKHLCGVATDLTLRSLTYNPDDNDFLQGVCIAMCCRHVCNSNNYVNPDFVKSIIGNTNTEEQLPYDQFFHALTKIAAWATSGDRPTSSDENNTHFTNLPYTERQELGLMARRVIDQGRCDWLQQKLGESFKVELIRYVEPSISLENVALLAYRK

Protein

tRNA:m(4)X modification enzyme TRM13: TRM13

Gene

TRM13

Protein

tRNA:m(4)X modification enzyme TRM13

Organism

Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)

Length

420 amino acids

Function

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

Similarity

Belongs to the methyltransferase TRM13 family.

Mass

48.427 kDa

Sequence

MIKKNRRCAMRRKGSQKYCSEHIIYNESSSIVNTDTKLSEDERVPCPLDGKHTVWKKNLAVHLKKCNAKPVERTEEWFSKDINVKLKNSLGETEDITRSEDKTLDEKDLYSKYIPIIEGINFEPLQYRISEHSGLQQRLNEVLIQKHALQQSSLIGNIKDAKLLSPNNTFVEFGCGKAELSRFVNLCLLDDLKQKVNNEVTLENYGYGFIDRGVNRMKMDKKILKDCLDSPIEITPRIQRTRIDIKDLDLDKFINKLQPSKIVAISKHLCGAATDLTLKSLLNSSLLSDNRDKFGGLLIAMCCRHVCSYDQLLPKSREYLAEKGFKTPDSFRILKKMVSWAVCSKKEHAKNVERLEAEHISQLDYSSRERLGFVARRLIDESRVYALKSMLSGFEVKMFWYVEKDVTLENVCLYVGQEPM

Protein

tRNA:m(4)X modification enzyme TRM13: TRM13

Gene

trm13

Protein

tRNA:m(4)X modification enzyme TRM13

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

368 amino acids

Function

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

Similarity

Belongs to the methyltransferase TRM13 family.

Mass

42.666 kDa

Sequence

MARIKKIFTQEELKQIPCPYDHKHTIVRHRLEYHLKRCNARPVERTDPYYKKDINISTSTDASESSSFEIVDLSKEELSKWICLFNRISDSLPTPQKKVLFHPAMNARLEEGTKKKHAIQQASLLGHMEKLHYFDNQGSIYYEFGAGRAELSRYVQHCSQQENVYILIDRDSNRTKHDSRILKDSIKNNWPEPKIIRCKIDIKDLKLDFFASEFRNSGKPVFAYSKHLCGAATDLTLNCLKSSPPNALVIALCCHHHCRWRTLSTFAREQLSHWGISNPQEFQILRQMTGWAVNSLREHMHASGGADSHISGLSHEERVKIGLKCKHIINYMRKLECEKMGYESSLVYYVGEETTLENVALIAYKRIN

Protein

tRNA:m(4)X modification enzyme TRM13: trm13

Gene

TRM13

Protein

tRNA:m(4)X modification enzyme TRM13

Organism

Oryza sativa subsp. japonica

Length

250 amino acids

Function

tRNA methylase that catalyzes 2'-O-methyladenosine (Am) nucleoside formation on tRNA(Gly)(GCC) in vitro. May 2'-O-methylate cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His) (PubMed:28369540). Involved in salt stress tolerance (PubMed:28369540).

Similarity

Belongs to the methyltransferase TRM13 family.

Mass

27.114 kDa

Sequence

MGRAPAKRKPSSPPPPPPPGRCHFWLPNKRRHCANTPLPTSQYCGNHLPDSASDAGAPFRRLVPCPVDPSHTVLEENLEAHVGKCPLKKQAAALAAQPFYSKGINSGGGEGGGGVTSAAKRALVHKLTKDELRALIEKIKLAHASAAMAMRDSFLVTDACDNWMRNQVDRKVPYQEKHVTQQASIIGNMEAFGLLQKGGEVAEENGVKNAPAVVEFGAGRGYLTQMLADCYGIRNVFLVERRSYKLKLKI

Protein

tRNA:m(4)X modification enzyme TRM13: TRM13