About Products Protein Database Contact

TONSL

Gene
tonsl
Protein
Tonsoku-like protein
Organism
Danio rerio
Length
1427 amino acids
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks.
Similarity
Belongs to the Tonsoku family.
Mass
158.305 kDa
Sequence
MTSTKEIKQLQKAKSKAQSSNNLKEEASLCNQLGEVYAKTGDYQAAIEEHRQELALSEILHDVIGSAVANRKIGECYAELGNIEAALKHQRLHLNLARSVHDAAEEQRALATIGRTYLFLFDSDQSANSLKHAEDAFKRSLAIVDERLEGTVSPREISEMKARLLLNLGCVYDGMKEPQRCSDLIRQSIYIAEKNNLLEDLYRANFNLGSIHFRNGQHSRAMRCFEQSKECARKMKDKFSESECFHSIGKILLHLGDFSAARRSLKKAFCLGSQQPSDREAVKKDFRHAIRGCQLEQTAAEVTQKFSHEALDLSEQLGDLYCKVGCYSKALEAYQTQLACAEALAKPARELAVIHVSLAATYTDLRQHHRAVEHYRQELQLRKGNPKEECETWLNMAVCQEEMCQSMETLDHCFTSALNCAEKSGLNKLQRRVLRVWLQAQRRCGSSQCDDTEARLMELCERDGLSLDQSEDEDEEDEVDNSEPLEDSDIQYSESDDEDLEGYDKMVTGRRKTQRWNRRNEKGETVLHRACIEGNLKQVQYLIEQGHPVNVRDYCGWTPLHESCNYGHQEIVAFLLDRGANVNDPGGRECGGITPLHDTLSCGHFSVARLLVLRGASVTVRNSKGHTPLDTLRQWFKTYSGQLDPETKQECLETEKLIKRALSGDVSVVCAAPRQQKELQDSQLFDAEYSEPLLRESPPSPPPITRPAATVPTSKDSAPKHRSTSASTRRPRGMEVDVLYGDDSSSSDNPDSDCSLSPLRPVRSRPRSPPAQSPQEVPSSQELPSVYGIKETTVPPQSESGRLEYQKAMQNLGSAKSRLFSQSLSDPAFTSTPAVSANSRAALVPEDQYLADDWLEDDLIDMQPKKKRRVSEHNATRETTSRSQNNSSTIAEVPPRVQSCSSRGSLSLKKGSNKPRQVKMNQLPGMVMLGRREVSRSQSPIMTQESDHIQEPAPPSHQAMPPASFQNRAAHVPAPIRMRVKVQDNVFLIPVPHSEADSCTVAWLCDQAAQRYYQMCGLLPRLSLQKEGALLLPTDPLLAVLHTNEEVLAEVCSWDLPPLPERYRKACESLGVEENRRVSRVCEVQDSSSCVSVCGLSLSPASLNPLLRALKLQASLTELRISANRLNDELLPEMMAAAATMPRLRVLDISANQITGEGLRKASDAFETRSQAAFPCLEELNLSMNPLGDGWTQALASLLSSCPLLSSLSLQACGLSARFLQQHRLLLANAMASTGNMRSVCLSHNALGSTGFELVLKTLPMHCLTHLELSAVCRGPSDQPSMEILTKLLAQGDCPLTHLNLSGNGLTDHSVLLLARCLPVCPSLVSLDLSANPLVTSTGLHSLLNGLVEARRPLGHLNLQGCQVSGPLAEDCLDSLSDHIRDLRLCSQSLNKLDQDALQQSWKRRTEAVHIFSRNSKCMLSISSPSH
Protein
Tonsoku-like protein: tonsl

Gene
TONSL
Protein
Tonsoku-like protein
Organism
Homo sapiens
Length
1378 amino acids
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, may act as a scaffold.
Similarity
Belongs to the Tonsoku family.
Mass
150.929 kDa
Sequence
MSLERELRQLSKAKAKAQRAGQRREEAALCHQLGELLAGHGRYAEALEQHWQELQLRERADDPLGCAVAHRKIGERLAEMEDYPAALQHQHQYLELAHSLRNHTELQRAWATIGRTHLDIYDHCQSRDALLQAQAAFEKSLAIVDEELEGTLAQGELNEMRTRLYLNLGLTFESLQQTALCNDYFRKSIFLAEQNHLYEDLFRARYNLGTIHWRAGQHSQAMRCLEGARECAHTMRKRFMESECCVVIAQVLQDLGDFLAAKRALKKAYRLGSQKPVQRAAICQNLQHVLAVVRLQQQLEEAEGRDPQGAMVICEQLGDLFSKAGDFPRAAEAYQKQLRFAELLDRPGAERAIIHVSLATTLGDMKDHHGAVRHYEEELRLRSGNVLEEAKTWLNIALSREEAGDAYELLAPCFQKALSCAQQAQRPQLQRQVLQHLHTVQLRLQPQEAPETETRLRELSVAEDEDEEEEAEEAAATAESEALEAGEVELSEGEDDTDGLTPQLEEDEELQGHLGRRKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQGHPLNPRDYCGWTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGASVTLRTRKGLSPLETLQQWVKLYRRDLDLETRQKARAMEMLLQAAASGQDPHSSQAFHTPSSLLFDPETSPPLSPCPEPPSNSTRLPEASQAHVRVSPGQAAPAMARPRRSRHGPASSSSSSEGEDSAGPARPSQKRPRCSATAQRVAAWTPGPASNREAATASTSRAAYQAAIRGVGSAQSRLGPGPPRGHSKALAPQAALIPEEECLAGDWLELDMPLTRSRRPRPRGTGDNRRPSSTSGSDSEESRPRARAKQVRLTCMQSCSAPVNAGPSSLASEPPGSPSTPRVSEPSGDSSAAGQPLGPAPPPPIRVRVQVQDHLFLIPVPHSSDTHSVAWLAEQAAQRYYQTCGLLPRLTLRKEGALLAPQDLIPDVLQSNDEVLAEVTSWDLPPLTDRYRRACQSLGQGEHQQVLQAVELQGLGLSFSACSLALDQAQLTPLLRALKLHTALRELRLAGNRLGDKCVAELVAALGTMPSLALLDLSSNHLGPEGLRQLAMGLPGQATLQSLEELDLSMNPLGDGCGQSLASLLHACPLLSTLRLQACGFGPSFFLSHQTALGSAFQDAEHLKTLSLSYNALGAPALARTLQSLPAGTLLHLELSSVAAGKGDSDLMEPVFRYLAKEGCALAHLTLSANHLGDKAVRDLCRCLSLCPSLISLDLSANPEISCASLEELLSTLQKRPQGLSFLGLSGCAVQGPLGLGLWDKIAAQLRELQLCSRRLCAEDRDALRQLQPSRPGPGECTLDHGSKLFFRRL
Protein
Tonsoku-like protein: TONSL

Gene
TONSL
Protein
Tonsoku-like protein
Organism
Bos taurus
Length
1374 amino acids
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, may act as a scaffold (By similarity).
Similarity
Belongs to the Tonsoku family.
Mass
150.245 kDa
Sequence
MSLERELRQLSKAKTKAQRSGQLREEASVCHQLGELLASHGCYAEALREHQQELQLLETTDDPLGCAVAHRKIGERLAEMEDYSAALQHQHRYLELACALSNHVEQQRAWATIGRTHLDIYDHHQSQDALQQAQDAFEKSLAILDEKLQGSLPKRELSEMRTRIYLNLGLTCESLQQVALCSAYFKKSIFLAEQNHLYEDLFRARYNLGAIHWRRGQHSQAMRCLEGARECARVLKQAFLESECCLLLSQVLLDLGDFLAAKRALKKAYRLGSQKPLQKASVCRTLKYVLAVVQLQQRLEESEESDPEVAMGICEQLGDLFSKAGDFPKAAAAYQKQLRFAELLSRPGPELAVIHVSLAATLGDMKDHRQAVHHYEAELKLQEGNPLEEAKTWLNIALSREEAGDAYEVLALCFQKALGCAQLAGQPQLQRQILQHLHAVQLRLQPQEAPSTETRLQELKAAGDEDEGDGEDEEDEEDDDALEATELELSESENEADASPPLEEDEELRGCLGRQRVNKWSRRNDVGETLLHRACIEGQLGRVQDLVRQGHPLNPRDYCGWTPLHEACNYGHLDIVRFLLDHGAAVDDPGGQGCDGITPLHDALNCGHFEVAELLIERGASVTLRTRKGHNPLETLQQWVKLYGKDLDSETQEKAAAMGRLLQAASLGRAPHSSQAPQTLPSNHLFDPETSPPSSPCPGTPEVCEASTRVSQGLAVSTVARPRRSRHKVASSSSSEGEDSAGPSQPTQKRPRHASPSLQTKAPMPGPASDREAATTSTSWAAYREAIRGVGSAQTCRLGPSPLRGPSEIPIPQAALIPQEECLAGDWLEEDFPMSPGHRGRCPARPQSSGDGGRHRASGPGSDTARRPRAQARQSRLPYLESWSTPVRADRANSQATEPARSPDVPRVVAPTGENPTTGHLPGQVLPPPIRVRVRVQDNLFLIPVPHREAHSVAWLAEQAAQRHYQASGLLPRLSLQKEGALLAPQDPIPDVLQSNEEVLAEVTSWDLPPLRDRYRRACQTLEQGEHQQVLQAVEHQGSAPTFSACSLALRQAQLTPLLRALKLHSALRELRLAGNRLGDGCVAELLATLDTVPGLTLLDLSSNHLGPEGLRQLAAGLLGQTTLQNLEELDLSMNPLGDGCGQALASILRACPVLCTLHLQACGFGPGFFLSHQVALGSAFQDTKCLKTLSLSYNGLGPTALGPVLGSLPAHSLLRLELSSVVTGKSDVGLTDPVVHYLSQEGCVLEHLSLSANHLGDKDVRALSRCLPLCPSLVSLDLSANPEVSSAGLEELLSTLQKRPQGLSFLGLSGCAVQGPLGLDLWDKVVAQLQELQLCTRRLSAEDRNALHQLLPSQLGPKVCTLDQGPKLFFRHL
Protein
Tonsoku-like protein: TONSL

Gene
Tonsl
Protein
Tonsoku-like protein
Organism
Rattus norvegicus
Length
1367 amino acids
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, may act as a scaffold (By similarity).
Similarity
Belongs to the Tonsoku family.
Mass
151.834 kDa
Sequence
MTLEQELRQLSKAKARAQRNGQLCEEAVCCHQLGELLASHGRFQEALEEHQQELHLLESVQDTLGCAVAHRKIGERLAEMENYSAALKHQHLYLDLAGSLSNHTELQRAWATIGRTHLDVYDHCQSRDSLLQAQAAFEKSLAIVDEKLEGMLTQRELSEMRTRLYLNLGLTCESLQQTAQCNNYFKKSIFLAEQNHLYEDLFRARYNLGAIHWRGGQHSQAMRCLEGARECARAMKMRFMESECCMLVSQVLQDLGDFLAAKRALKKAYRLGSQKPNQRVAICQSLKYVLAVVRLQQQLQEAEGNDLQGAMAICEQLGDLFSKADDFPKASEAYQKQLHFAELLNRPDLELAVIHESLATTLGDMKDYHKAVHHYEEELRLRKGNALEEAKTWFNIGLAREEAGDAYELLAPCFQKAFGCAQQAQRYQLQRQILQHLYTVQLKLQPQEARDTEIRLQELSMAKDTEEEEEEEEEEEEEASEALETSEMELSESEDDADGLSQQLEEEEELQGCVGRRKINKWNRRNDMGETLLHRACIEGQLRRVQDLVKQGHPLNPRDYCGWTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCDGITPLHDALNCGHFEVAELLIERGASVTLRTRKGLSPLETLQQWVKLYFRDLDLETRQKAASMERRLQMASSGQASHSSPALQTIPNNHLFDPETSPPSSPCPKPPSYTPRPPEASPAPAKVFLEETVSAVCRPRKNRHRPASSSSSSEDDDDNTNPCRPSQKRLRHSTQQGEAKTPDPSKSRETAISSACRAAYQAAIRGVGSAQSRRLVPSLPRGSNEVPAPKTALIPEEEFLAEEWLEVDTPLTRSSSSSRPSTSISDYERCPARPRTRAKQSRPASLDGWCTRTKAADASLTAEPTENSSMPRTTGPNKENCAAGQPLLLVQPPPIRVRVQIQDNLFLIPVPHSDVHSVAWLAEQAAQRYFQTCGLLPRLTLRKDGALLAPQDPIPDVLQSNDEVMAEVTSWDLPPLKDRYRRACQSLGQGEHQQVLQAMEHQSSSPSFSACSLALCQAQLTPLLRALKLHTALRELRLSGNRLGDPCATELLATLGTMPNLVLLDLSSNHLGPEGLRQLVEGSLGQTAFQNVEELDLSMNPLGDGCAQALASLLRTCPVLRTLRLQACGFSPSFFLSHQAALGSAFKDAEHLKTLSLSYNTLGAPALARVLQSLPTCTLLHLELSSVAASKSNSSLIEPVIKYLTKEGCALAHLTLSANCLSDKAVRELSRCLPSCPSLTSLDLSANPEVSCAGLEELLSALQERPQGLSFFDLSGCSIQGPLNSDLWDKILSQLQELQLCSKDLTTKDRDTLCQRLPAGACTLNQGSKLFFKCL
Protein
Tonsoku-like protein: Tonsl

Gene
Tonsl
Protein
Tonsoku-like protein
Organism
Mus musculus
Length
1363 amino acids
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, may act as a scaffold (By similarity).
Similarity
Belongs to the Tonsoku family.
Mass
151.108 kDa
Sequence
MTLEQELRQLSKAKTRAQRNGQLREEAAYCHQLGELLASHGRFKDALEEHQQELHLLESVQDTLGCAVAHRKIGERLAEMENYSAALKHQHLYLDLAGSLSNHTELQRAWATIGRTHLDIYDHCQSRDSLLQAQAAFEKSLAIVDEKLEGMLTQRELSEMRTRLYLNLGLTCESLQQTALCNNYFKKSIFLAEQNHLYEDLFRARYNLGAIHWRGGQHSQAMRCLEGARECARAMKMRFMESECCVLVSQVLQDLGDFLAAKRALKKAYRLGSQKPNQRVTVCQSLKYVLAVIQLQQQLEEAEGNDLQGAMAICEQLGDLFSKAGDFPKAAEAYQKQLHLAELLNRPDLELAVIHVSLATTLGDMKDHRKAVHHYEEELRLRKGNALEEAKTWFNIALSREEAGDAYELLAPCFQKAFCCAQQAQRFQLQRQILQHLYTVQLKLQPQEARDTEIRLQELSMAKDTEEEEEEEEEEEEEASEAPETSELELSESEDDADGLSQQLEEDEELQGCVGRRKVNKWNRRNDMGETLLHRACIEGQLRRVQDLVKQGHPLNPRDYCGWTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCDGITPLHDALNCGHFEVAELLIERGASVTLRTRKGLSPLETLQQWVKLYFRDLDLETRQKAATMEERLQMASSGQASRSSPALQTIPSNHLFDPETSPPSSPCPEPSSYTPRPPEASPAPAKVFLEETVSAVSRPRKTRHRPTSSSSSSEDEDNPSPCRPSQKRLRHTTQQGEVKIPDPPKSRETATSSACRAAYQAAIRGVGSAQSRRLVPSLPRGSEEVPAPKTALIPEEEYLAGEWLEVDTPLTRSGRPSTSVSDYERCPARPRTRVKQSRLTSLDGWCARTQAGDGSLNAEPAENPSVPRTSGPNKENYAAGQPLLLVQPPPIRVRVQIQDNLFLIPVPQSDIRPVAWLTEQAAQRYFQTCGLLPRLTLRKDGALLAPQDPIPDVLQSNDEVLAEVTSWDLPPLKDRYRRACLSLGQGEHQQVLHAMDHQSSSPSFSACSLALCQAQLTPLLRALKLHTALRELRLAGNRLGDACATELLATLGTTPNLVLLDLSSNHLGQEGLRQLVEGSSGQAALQNLEELDLSMNPLGDGCGQALASLLRACPMLSTLRLQACGFSSSFFLSHQAALGGAFQDAVHLKTLSLSYNLLGAPALARVLQTLPACTLKRLDLSSVAASKSNSGIIEPVIKYLTKEGCALAHLTLSANCLGDKAVRELSRCLPCCPSLTSLDLSANPEVSCASLEELLSALQERSQGLSFLGLSGCSIQGPLNSDLWDKIFVQLQELQLCTKDLSTKDRDSVCQRLPEGACTMDQSSKLFFKCL
Protein
Tonsoku-like protein: Tonsl