Function
Promotes cell fate progression in stomatal development. In leaves, needed to correctly orient spacing divisions, to limit the number of asymmetric divisions in neighbor cells, and to promote the asymmetric (amplifying) divisions of meristemoids. In stems, promotes the conversion of meristemoids into guard mother cells (GMC) (PubMed:11090210, PubMed:12040198, PubMed:18979118). Positively regulates CAPRICE (CPC) expression in differentiating stomaless-forming cell files (PubMed:19513241). Forms constitutive complexes with ERECTA and ERL1 involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN (PubMed:28536146). Modulates the activity of the ligand-receptor pairs EPF2-ERECTA and EPF1-ERL1 in stomatal development (PubMed:16002616, PubMed:22241782). Functions in a combinatorial specific manner with the ERECTA-family (ERf) receptor kinases in the regulation of the immune response (PubMed:27446127).
Sequence
MARYEFFRQIFIVLSIVSPLVRSFTVITSDSTAPSALIDGPQTGFTMTNDGARTEPDEQDAVYDIMRATGNDWAAAIPDVCRGRWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDPQRSYVSESLTRLKHLKALFFYRCLGRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHLEGNNLTGEIPLEFRDVKHLSELRLNDNSLTGPVPFERDTVWRMRRKLRLYNNAGLCVNRDSDLDDAFGSKSGSTVRLCDAETSRPAPSGTVQHLSREEDGALPDGATDVSSTSKSLGFSYLSAFFLVFPNFIFMLISS