About Products Protein Database Contact

TMEFF1

Gene
TMEFF1
Protein
Tomoregulin-1
Organism
Homo sapiens
Length
380 amino acids
Function
May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.
Similarity
Belongs to the tomoregulin family.
Mass
40.934 kDa
Sequence
MGAAAAEAPLRLPAAPPLAFCCYTSVLLLFAFSLPGSRASNQPPGGGGGSGGDCPGGKGKSINCSELNVRESDVRVCDESSCKYGGVCKEDGDGLKCACQFQCHTNYIPVCGSNGDTYQNECFLRRAACKHQKEITVIARGPCYSDNGSGSGEGEEEGSGAEVHRKHSKCGPCKYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHCTDTDDTSLLGKKDDGLQYRPDVKDASDQREDVYIGNHMPCPENLNGYCIHGKCEFIYSTQKASCRCESGYTGQHCEKTDFSILYVVPSRQKLTHVLIAAIIGAVQIAIIVAIVMCITRKCPKNNRGRRQKQNLGHFTSDTSSRMV
Protein
Tomoregulin-1: TMEFF1

Gene
Tmeff1
Protein
Tomoregulin-1
Organism
Rattus norvegicus
Length
373 amino acids
Function
May inhibit NODAL and BMP signaling during neural patterning.
Similarity
Belongs to the tomoregulin family.
Mass
40.143 kDa
Sequence
MGAQAPLRLPAAPPLAVCGYTSVLLLFAFCLPGSGASNQPAGGGGDCPGGRGKSINCSELNLRESDIRACDESSCKYGGVCKEDGDGLKCACQFQCHTNYIPVCGSNGDTYQNECFLRRAACKHQKDITVVARGPCYSDNGSGSGEGEEEGSGAGAHRKHSKCGPCKYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIRQEQIDIRHLGHCTDTDDTSLLGKKDDGLQYRPDVKDAGDQREDVYIGSHMPCPENLNGYCIHGKCEFIYSTQKASCRCESGYTGQHCEKTDFSILYVVPSRQKLTHVLIAAIIGAVQIAIIVAIVMCITRKCPKNNRGRRQKQNLGHFTSETSSRMV
Protein
Tomoregulin-1: Tmeff1

Gene
Tmeff1
Protein
Tomoregulin-1
Organism
Mus musculus
Length
372 amino acids
Function
May inhibit NODAL and BMP signaling during neural patterning.
Similarity
Belongs to the tomoregulin family.
Mass
40.114 kDa
Sequence
MGAQAPLRLPAAPPLAVCGYTSVLLLFAFCLPGSRASNQPAGGGGDCPGGRGKSNCSELNLRESDIRVCDESSCKYGGVCKEDGDGLKCACQFQCHTNYIPVCGSNGDTYQNECFLRRAACKHQKDITVVARGPCYSDNGSGSGEGEEEGSGAGAHRKHSKCGPCKYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHCTDTDDVSLLGKKDDGLQYRPDVKDAGDEREDVYIGSHMPCPENLNGYCIHGKCEFIYSTQKASCRCESGYTGQHCEKTDFSILYVVPSRQKLTHVLIAAIIGAVQIAIIVAIVMCITRKCPKNNRGRRQKQNLGHFTSDTSSRMV
Protein
Tomoregulin-1: Tmeff1

Gene
tmeff1
Protein
Tomoregulin-1
Organism
Xenopus laevis
Length
370 amino acids
Function
Inhibits nodal/nr-1 and bmp signaling during neural patterning through interaction with cripto.
Similarity
Belongs to the tomoregulin family.
Mass
40.33 kDa
Sequence
MDGLHPASWMLLLGSLAFWSASSLLLFSLALPGARASNQLLSECHNGKGKGINCSELTVRESEVRVCDESSCKYGGVCKEEGDVLKCICQFQCQTNYAPVCGSNGDTYQNECFLRRSACKQQKDITVVARGPCFSDIASGSGEGEYEGSGGEVHKKHSKCGVCKFGAECDEDAGDVGCVCNIDCSGHNFNPVCATDGSSYSNPCLVREASCLRQEQIDVKHIRSCIETDETSIMGKKDEGLQNRPEVKDSTDQREGDFMGNYIPCSENYNGYCVHGKCELSYSSQKASCRCDSGYTGQYCDKTDFNILYVVPSRQKLTHVLIAAIIGAVQIAIIVAIVMCITRKCPKNNRGRRQKQNLGHFSSDTSSRMV
Protein
Tomoregulin-1: tmeff1