TM7SF2

Delta(14)-sterol reductase

418 amino acids

Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis.

Belongs to the ERG4/ERG24 family.

46.751 kDa

MAPPQGSRAPLEFGGPLGAAALMLLLPVTMFHLLLVARSGPARLLGPPPYLPGPEELWSPWALLLCLTWLGLQAALYLLPARKVAEGQELKDKSRLRYPTNGFQALVLTALLVGLGVSAGLPLSALPEMLLPLAFAATLTAFIFSLLLYLKALLAPASALAPGGNSGNLIYDFFLGRELNPRICSFDFKYFCELRPGLIGWVLINLALLIQEAELRGSPSLAMWLVNGFQLLYVGDALWYEEAVLTTMDIIHDGFGFMLAFGDLAWVPFTYSLQAQFLLYHPQPLGWPLASFICLINAVGYYIFRGANSQKNTFRKNPSDPRVADLETISTATGRRLLVSGWWGMVRHPNYLGDLIMALAWSLPCGVFHLLPYFYFLYFTALLVHREDRDERQCRQKYGLAWHEYCRRVPYRIVPYVY

TM7SF2

Delta(14)-sterol reductase

418 amino acids

Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis.

Belongs to the ERG4/ERG24 family.

46.406 kDa

MAPTQGPRAPLEFGGPLGAAALLLLLPATMFHLLLAARSGPARLLGPPASLPGLEVLWSPRALLLWLAWLGLQAALYLLPARKVAEGQELKDKSRLRYPINGFQALVLTALLVGLGMSAGLPLGALPEMLLPLAFVATLTAFIFSLFLYMKAQVAPVSALAPGGNSGNPIYDFFLGRELNPRICFFDFKYFCELRPGLIGWVLINLALLMKEAELRGSPSLAMWLVNGFQLLYVGDALWHEEAVLTTMDITHDGFGFMLAFGDMAWVPFTYSLQAQFLLHHPQPLGLPMASVICLINATGYYIFRGANSQKNTFRKNPSDPRVAGLETISTATGRKLLVSGWWGMVRHPNYLGDLIMALAWSLPCGVSHLLPYFYLLYFTALLVHREARDERQCLQKYGLAWQEYCRRVPYRIMPYIY

Tm7sf2

Delta(14)-sterol reductase

418 amino acids

Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis.

Belongs to the ERG4/ERG24 family.

46.521 kDa

MTSREASQAPLEFGGPLGVAALLILLPATMFHLLLAARSGPARLLALPAYLPGLEELWSPWALLLLFIWLGLQVALYLLPARKVAEGLELKDKSRLRYPINGFQALVLTALLMGLGVSVGLPLGALPGMLLPLAFATTLTSFIFSLLLYAKALVAPASALAPGGNSGNSMYDFFLGRELNPRLGSFDFKYFCELRPGLIGWVFINLALLMQEAELRGSPSLAMWLVNGFQLLYVGDALWYEESVLTTMDIIHDGFGFMLVFGDLAWVPFTYSLQAQFLLYHPQPLGLPMALLICLLKVIGYYIFRGANSQKNTFRKNPSDPSVAGLETIPTATGRQLLVSGWWGMVRHPNYLGDLIMALAWSLPCGLSHLLPYFYVLYFTALLVHREARDEQQCLQKYGRAWQEYCKRVPYRIIPYVY