TM6SF2

Gene

Tm6sf2

Protein

Transmembrane 6 superfamily member 2

Organism

Mus musculus

Length

378 amino acids

Function

Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content. May function as sterol isomerase.

Similarity

Belongs to the TM6SF family.

Mass

43.027 kDa

Sequence

MDIPPLAGRTVAMSFCALPVSYLLNQVSAFSQPLFVVLTSALILGLLFLAVYSLSHGEITYDPLYAVFVIFSFTSVVDLVIALQEDGYMMGFMDFYTKEGEPYLRTAHGIFICYWDGTVHYLLYLTMAGAIRKRKRYRNLGLYWLGSFAMSILVFLPGNILGKYSSEMRPTFFLAILYMLVPCWAGVRIFNQSRAPTSYTPDMVQEEQKKSLLQRPADLALIVYLIFAALFTVFRGLVVLDCPTDACFIYIYQYEPYLRDPVAYPKLQMLMYLFYALPFYCLAAYALAFPGCSWLPDWALVFAGAIGQAQFSHMGASMHMRTPFTYRVPEDTWATFFLSNLLLALGPHLLAFRCLWRPAFFLHAALPSSPQDQDKKQQ

Protein

Transmembrane 6 superfamily member 2: Tm6sf2

Gene

Tm6sf2

Protein

Transmembrane 6 superfamily member 2

Organism

Rattus norvegicus

Length

378 amino acids

Function

Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content. May function as sterol isomerase.

Similarity

Belongs to the TM6SF family.

Mass

42.574 kDa

Sequence

MDIPPLAGRTVAMSLGALPVSYVLNQVSAFSQPLCVVLTSALVLGLLFMAVYSLSHGEITYDPLYAVFVVFSFTSVVDLVIALQEDGYLMGLMDFYAKEGEPYLRTAHGIFICYWDGTVHYLLYLTMAGAIRKRKRYRNLGLYWLGSFAMSLLVFLPGNILGKYSSEIRPTFFLAILYMLVPCWAGMRIFNQSPAPSSCTCDVVQEEQKKSLLQRPADLTLIVYLILAAFFTVFRGLVVLDCPADACFIYIYQYEPYLRDPVAYPKLQMLMYLFYALPFYCLAAYALTFPGCSWLPDWALVFAGAIGQAQFSHMGASMHLRTPFTYRVPEDTWATFLLSNLLFALGPHLLALRCLWRPAFFLRAAPPSSPQDQGKKQQ

Protein

Transmembrane 6 superfamily member 2: Tm6sf2

Gene

TM6SF2

Protein

Transmembrane 6 superfamily member 2

Organism

Homo sapiens

Length

377 amino acids

Function

Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content (PubMed:24531328, PubMed:24927523). May function as sterol isomerase (PubMed:25566323).

Similarity

Belongs to the TM6SF family.

Mass

42.554 kDa

Sequence

MDIPPLAGKIAALSLSALPVSYALNHVSALSHPLWVALMSALILGLLFVAVYSLSHGEVSYDPLYAVFAVFAFTSVVDLIIALQEDSYVVGFMEFYTKEGEPYLRTAHGVFICYWDGTVHYLLYLAMAGAICRRKRYRNFGLYWLGSFAMSILVFLTGNILGKYSSEIRPAFFLTIPYLLVPCWAGMKVFSQPRALTRCTANMVQEEQRKGLLQRPADLALVIYLILAGFFTLFRGLVVLDCPTDACFVYIYQYEPYLRDPVAYPKVQMLMYMFYVLPFCGLAAYALTFPGCSWLPDWALVFAGGIGQAQFSHMGASMHLRTPFTYRVPEDTWGCFFVCNLLYALGPHLLAYRCLQWPAFFHQPPPSDPLALHKKQH

Protein

Transmembrane 6 superfamily member 2: TM6SF2