TKFC

Gene

TKFC

Protein

Triokinase/FMN cyclase

Organism

Sus scrofa

Length

579 amino acids

Function

Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate (PubMed:7831203). Represses IFIH1-mediated cellular antiviral response (By similarity).

Similarity

Belongs to the dihydroxyacetone kinase (DAK) family.

Mass

59.234 kDa

Sequence

MTSKKLVNSVAGCADDALAGLVACNPSLQLLQGHRVALRSDLDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVAQAGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVVGDDSAFTVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEEITNRVSVVAKAMGTLGVSLSSCSVPGSRPTFELSADEVELGLGIHGEAGVLRIKMATADEIVAHMLNHMTDSSNVSHVPVQSGSSVVLMVNNLGGLSYLELGIIADAAVRFLEGRGVKIARALVGTFMSALEMPGVSLTLLLVDEPLLKLIDAETTAAAWPNVAKVSVTGRKRSRAAPAEPPEAPDATAAGGATSKQMVRVLERVCTTLLGLEDQLNALDRAAGDGDCGTTHSRAARAIQGWLKESPPPASPAQLLSKLSLLLLEKMGGSSGALYGLFLTAAAQPLKAKTDLAAWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGANLLPVLTKALLENAEAAAEATKNMEAGAGRASYISSARLDQPDPGAVAAAAILRAILEVLQSQGA

Protein

Triokinase/FMN cyclase: TKFC

Gene

TKFC

Protein

Triokinase/FMN cyclase

Organism

Bos taurus

Length

578 amino acids

Function

Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response.

Mass

59.124 kDa

Sequence

MTSKKLVNSVAGCADDALAGLVACNPSLQLLQGHRVALRSDLDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVAQAGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVVGDDSAFTVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEEITDRVSVVAKAMGTLGVSLSSCSVPGSKPTFELSADEVELGLGIHGEAGVRRIKMATANEIVALMLDHMTSSSNASHVPVPPGSSVVLMVNNLGGLSFLELGIIADAAVCSLEGHGVKIARALVGTFMSALEMPGVSLTLLLVDEPLLKLIDAETTASAWPNVAKVWVTGRKRSRAAPTEPLAAPDSTTAAGEASKQMVLVLEWVCTTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIXGWLKEGPPPASPAQLLSKLSFLLLEKMGGSSGALYGLFLTAAAQPLKAKTDLPAWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGANMLQILTKAVKSAEAAAEATKNMEAGAGRASYISSARLDQPDPGAVAAAAILRAILEVLQSQGA

Protein

Triokinase/FMN cyclase: TKFC

Gene

Tkfc

Protein

Triokinase/FMN cyclase

Organism

Mus musculus

Length

578 amino acids

Function

Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response.

Similarity

Belongs to the dihydroxyacetone kinase (DAK) family.

Mass

59.691 kDa

Sequence

MSSKKMVNSVEGCADDALAGLVASNPDLQLLQGHRVALRSDLDTLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGSVFASPPVGSILAAIRAVAQAGTVGTLLIVKNYTGDRLNFGLAMEQAKAEGISVEMVIVEDDSAFTVLKKAGRRGLCGTVLIHKVAGALAEEGMGLEEITKRVSVIAKTMGTLGVSLSSCSVPGATHTFELAADEIELGLGIHGEAGVRRIKIAPVDQIVTLMLDHMTNTSNIFHVPVRSGSSVVLIVNNLGGLSFLELGIIADAAIRLLEGRGVKVARALVGTFMSALEMPGVSLTLMLVDEPVLKLIDAETTAKAWPHMAKVSVTGRKRIRAAPTEPPEAPEATAAGGVTSKQMALVLDRICTTLIGLEEHLNALDRAAGDGDCGSTHSRAAKAIQGWLKEGPSLTSPAQVLSRLSVLLLERMGGSSGALYGLFLTAAAQPLKAKTDLPTWSAAMDAGLESMQKYGKAAPGDRTMLDSLWAAAQEFQAWKSPGASLLPVLTKAVKSAEAAAEATKNMEAGAGRASYISSAQLDQPDPGAVAAAAIFRAILEVLQTQGA

Protein

Triokinase/FMN cyclase: Tkfc

Gene

Tkfc

Protein

Triokinase/FMN cyclase

Organism

Rattus norvegicus

Length

578 amino acids

Function

Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate (PubMed:16289032). Represses IFIH1-mediated cellular antiviral response (By similarity).

Similarity

Belongs to the dihydroxyacetone kinase (DAK) family.

Mass

59.444 kDa

Sequence

MSSKKMVNSVEGCAGDALAGFVACNPDLQLLQGYRVALRSDLDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFASPAVGSILAAIRAVAQAGTAGTLLIVKNYTGDRLNFGLAMEQAKAEGISVEMVVIEDDSAFTVLKKAGRRGLCGTILIHKVAGALAEEGMGLEEITKKVSVIAKAIGTLGVSLSPCSVPGTKPTFELAADEMELGLGIHGEAGVRRIKLVPVDQIVTLMLDHMTDTSNISHVPVKSGSSVVLMVNNLGGLSFLELGIIADAAIRLLEGRGVKVARALVGTFMSALEMRGVSLTLMLVDEPLLKLIDAETNAKAWPHMSKVSVTGRNRIRAAPTEPAEAPEATAAGGVASKQMTLVLDRISTTLIGLEEHLNALDRAAGDGDCGSTHSRAAKAIQGWLKEGPTPASPAQVLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKANTDLPAWSAAMDAGLKAMQKYGKAAPGDRTMLDSLWAAAQELQAWKSPGASLLPVLTKAVKSAEAAAEATKNMEAGAGRASYISSAQLDQPDPGAVAAAAIFRAILEVLQTKAA

Protein

Triokinase/FMN cyclase: Tkfc

Gene

TKFC

Protein

Triokinase/FMN cyclase

Organism

Homo sapiens

Length

575 amino acids

Function

Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response (PubMed:17600090).

Similarity

Belongs to the dihydroxyacetone kinase (DAK) family.

Mass

58.947 kDa

Sequence

MTSKKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVAQAGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLMLDHMTNTTNASHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDEPLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEWLKEGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLPAWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATKNMEAGAGRASYISSARLEQPDPGAVAAAAILRAILEVLQS

Protein

Triokinase/FMN cyclase: TKFC