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TK1747

Gene
TK1747
Protein
Probable inosine/xanthosine triphosphatase
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Length
178 amino acids
Function
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
Similarity
Belongs to the YjjX NTPase family.
Mass
19.24 kDa
Sequence
MKVAVGSTNPAKVEAVREVFLGIYGDVEVVPIEVDSGVPDQPVGLEETVKGAINRAKQAIEKTDADFGVGIEAGLYRVPETITGYMDVQFCAVVDREGRITLGHGPGFEYPPGVIRRVFEEGVEVGIAMGELVNDPELKRKIGAIGVLTHGMLVRKELNKLAVLMALVPRLNPEWYGL