Protein
Eukaryotic translation initiation factor 3 subunit I
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Function
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Similarity
Belongs to the eIF-3 subunit I family.
Sequence
MRPIKLMGHERSLTQVKFNREGDLIFSVAKDSTASIWYSSNGERLGTLEGHIGTIWSIDVDADTILCATGSADLTIKLWKIETGECVQSWEMPTPVRRVAFSPDNKRLLAVTDQVMGQTGTISVFDINYEGDYTKQQSKPSLIIETRSDAKKVTVAGWSANGDFIIAGHEDGYVSKYNSSTGEFIETAQVHGIHNEEKIASITDIQFAPEDKSYIVTASKDKCSCLVDVDTLELMKVYKADAPMNTAAITPIKDFVILGGGQEARNVTTTAESQGKFEARFYHKIFIDEIGRVKGHFGPLNSIAVHPDGTGYASGGEDGFIRLHYFDKSYFDFEFDTERAERAMASSAA