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THG1L

Gene
THG1L
Protein
Probable tRNA(His) guanylyltransferase
Organism
Bos taurus
Length
298 amino acids
Function
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.
Similarity
Belongs to the tRNA(His) guanylyltransferase family.
Mass
34.74 kDa
Sequence
MWAAGALKVRDCLAATSVTLRRCLKLGATMAKSKFEYVRDFEADDTCLPHCWVVVRLDGRNFHRFAEKHSFIKPNDSRALHLMTKCAQTVMNELEDIVIAYGQSDEYSFVFKRKSNWFKRRASKFMTHVVSQFASSYVFYWRDYFEDQPLLYPPGFDGRVIVYPSNQTLKDYLSWRQADCHINNLYNTVFWALVQQSGLTPLQAQERLQGTLAADKNEILFSEFNINYNNEPLMYRKGTVLIWQKVEEITTKEVKLPAEMEGKKMAVTRTRTMVVPLHCNIIGDAFWKEHPEILDEDS

Gene
THG1L
Protein
Probable tRNA(His) guanylyltransferase
Organism
Homo sapiens
Length
298 amino acids
Function
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.
Similarity
Belongs to the tRNA(His) guanylyltransferase family.
Mass
34.831 kDa
Sequence
MWGACKVKVHDSLATISITLRRYLRLGATMAKSKFEYVRDFEADDTCLAHCWVVVRLDGRNFHRFAEKHNFAKPNDSRALQLMTKCAQTVMEELEDIVIAYGQSDEYSFVFKRKTNWFKRRASKFMTHVASQFASSYVFYWRDYFEDQPLLYPPGFDGRVVVYPSNQTLKDYLSWRQADCHINNLYNTVFWALIQQSGLTPVQAQGRLQGTLAADKNEILFSEFNINYNNELPMYRKGTVLIWQKVDEVMTKEIKLPTEMEGKKMAVTRTRTKPVPLHCDIIGDAFWKEHPEILDEDS

Gene
Thg1l
Protein
Probable tRNA(His) guanylyltransferase
Organism
Mus musculus
Length
298 amino acids
Function
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.
Similarity
Belongs to the tRNA(His) guanylyltransferase family.
Mass
34.971 kDa
Sequence
MWAFRTARIGSLLAATSVILRRCLRLGVAMAKSKFEYVRNFEVQDTCLPHCWVVVRLDGRNFHRFAEEHNFAKPNDSRALHLMTKCAQTVMEELEDIVIAYGQSDEYSFVFRKKSNWFKRRASKFMTLVASQFASSYVFYWRDYFEDQPLRYPPGFDGRVVLYPSNQTLKDYLSWRQADCHINNLYNTVFWALIQQSGLTPVQAQQRLKGTLTADKNEILFSEFHINYNNEPHMYRKGTVLVWQKVEEVRTQEVRLPAEMEGEKKAVARTRTRVVALNCDLIGDAFWKEHPEILAEEN

Gene
Thg1l
Protein
Probable tRNA(His) guanylyltransferase
Organism
Rattus norvegicus
Length
298 amino acids
Function
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.
Similarity
Belongs to the tRNA(His) guanylyltransferase family.
Mass
34.85 kDa
Sequence
MWAFSTARIGSPLAATSVTLRRCLRLGVAMAKSKFEYVRDFEVDDTCLPHCWVVVRLDGRNFHRFAEKHNFAKPNDSRALHLMTKCAQTVMQELEDIVIAYGQSDEYSFVFRKRSNWFKRRASKFMTLVASQFASSYVFYWRDYFEDQPLLYPPGFDGRVVLYPSNQTLKDYLSWRQADCHINNLYNTVFWALIQQSGLTPVQAQQRLKGTLTADKNEILFSEFHINYNNEPHMYRKGTVLVWQKVNEVRTQEIRLPAEMEGEKMAVTRTRTKLVALNCDLIGDAFWKEHPEILEGED