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TCF23

Gene
TCF23
Protein
Transcription factor 23
Organism
Bos taurus
Length
214 amino acids
Function
Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity).
Mass
23.439 kDa
Sequence
MSQREARGARAMPGLGQSPAKATPRLLAGTERKRSRLSRRGQDLWEESSWSNQRWSRTAPNPRGARARSLARGRSEASPENAARERSRVRTLRQAFLALQATLPAVPPDTKLSKLDVLVLATSYIAHLTRTLGQEMPGPSWPPFLRGLRYLHPLKKWPMRSRLYAGGLGCSGLDSTTASNSGQRTKEAEAGPHVSGEPDALLSTRQLSPAPSDK

Gene
TCF23
Protein
Transcription factor 23
Organism
Homo sapiens
Length
214 amino acids
Function
Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity).
Mass
23.309 kDa
Sequence
MSQRKARGPPAMPGVGHSQTQAKARLLPGADRKRSRLSRTRQDPWEERSWSNQRWSRATPGPRGTRAGGLALGRSEASPENAARERSRVRTLRQAFLALQAALPAVPPDTKLSKLDVLVLAASYIAHLTRTLGHELPGPAWPPFLRGLRYLHPLKKWPMRSRLYAGGLGYSDLDSTTASTPSQRTRDAEVGSQVPGEADALLSTTPLSPALGDK

Gene
Tcf23
Protein
Transcription factor 23
Organism
Mus musculus
Length
209 amino acids
Function
Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. May be involved in the regulation or modulation of smooth muscle contraction of the uterus during pregnancy and particularly around the time of delivery. Seems to play a role in the inhibition of myogenesis.
Mass
22.895 kDa
Sequence
MSQEATEAPAMPGEGHGHNKAKARWLLGTDRKRSRINRTRQDLWEDTSWSNHRLSRATSAPRGTRARGTAHGRSEASPENAARERTRVKTLRQAFLALQAALPAVPPDTKLSKLDVLVLATSYIAHLTRTLGHELPGPAWPPFVRGLRYLHPLKKWPMRSRLYAGGLGCSDLDSTTAITTGQRCKDAELGSQDSVAAESLLTSPAFGNK