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TBXT

Gene
TBXT
Protein
T-box transcription factor T
Organism
Halocynthia roretzi
Length
471 amino acids
Function
Involved in the transcriptional regulation of genes required for mesoderm differentiation.
Mass
52.417 kDa
Sequence
MSITNNMESPSDSEVRLTLNDRALWTKFCSLTNEMIVTKSGRRMFPVLKLTASGLEPNSMYSFLLDFAPADSNRWKYVNGEWVPGGKPEPHAASCVYVHPDSPNFGSHWMKQPVSFNKVKLTNKGNGGGQQIMLNSLHKYEPRIHVVKVGGEAASERTIATFSFPESQFIAVTAYQNEEVTSLKIKHNPFAKAFLDAKERPDQTDFHSLAGIPVSSPQVPSWYGRNGSTSSARHFTHCNSYGGESELTSVQDTAIPSYTSRNCMRNSYRGNARATPYTIPHKELTCQATSFPEPVPNDGFYPMFPNSELLPRTTLNNYSPAMGAYTNSSIVTSSDIQSGNNNNFFYSNNNNINTTDEVPTTYMTNDFNSFYNQSSNSGMPGTTYLPYQSSPVNQFYSYQPPYSTEIADISPTQQDIINAQNPYQTAWTPPLSYDGCSTMYNSITPYSSSGESTTSEMTLLATARYLQNLRL
Protein
T-box transcription factor T: TBXT

Gene
TBXT
Protein
T-box transcription factor T homolog
Organism
Patiria pectinifera
Length
453 amino acids
Function
May be involved in the transcriptional regulation of genes required for gastrulation.
Mass
49.376 kDa
Sequence
MSADTMRAPTYNVAHLLSAVQSEMTRGSEKGDPSEKGLKVTLEDRDLWRRFSKLTNEMIVTKTGRRMFPVLSASVTGLNPNAMYSILLDFTPADEHRWKYVNGEWVPGGKPDSPPPSTAYIHPDSPNFGAHWMKQCVSFSKVKLSNKLNGTGQIMLNSLHKYEPRIHVIRVGGPEKQRLIRSFSFPETQFIAVTAYQNEDITQLKIKYNPFAKAFLDIKEKGEHEFEDCHDHQQPRYPQLGSWFLPSAGTLCPPSPHHQFPPSLGMPSPVSHSCAVERYGSLRSHRSTPYPPPPYEQKYSPTSAYATDSTASSLSLLPAHEAWSPLGSSTHHTSNITTSPSHQYGGVWPPVTSSAVQPASSCGVGSPVHTSLLRAAYSNYSQPSTSSITGVPRPPAGSMSSSCAGYQNYNSPSEIHGGLNSTDAIGSYPTVGNQLCPGKVGAWSPLTPPSPGV
Protein
T-box transcription factor T homolog: TBXT

Gene
TBXT
Protein
T-box transcription factor T homolog 1
Organism
Branchiostoma floridae
Length
448 amino acids
Function
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation.
Mass
49.253 kDa
Sequence
MSSAETMKQPTAASPDQFSVSHLLSAVESEISAGSEKGDPTERDLKITLEEKPLWDKFNALTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFTAADNHRWKYVNGEWVPGGKPEPSVPSCVYIHPDSPNFGAHWMKSPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRLHIIKVGGPDNQRMVSTHTFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERSDGKDGMEDLQDQPQYSQLGGWFLPGTGPICPPPNPHQFAPSLGLPSHGCDRYSTLRNHRSAPYPHPYQRSSPPTNYGHDTAASLPMMPTHDNWSGLPVSTHNMLSMSAMPHTTTSTHAQYPNLWSVSNNNLTPTTHAQTHMSGTMGTGLPHQFLRTTAPAPYHSIPTCTVPTTASSSPVYHDSHEVSSTDSGYGHSTTPPAPQTRITSNNWSPMTPPSL
Protein
T-box transcription factor T homolog 1: TBXT

Gene
TBXT
Protein
T-box transcription factor T homolog 2
Organism
Branchiostoma floridae
Length
440 amino acids
Function
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation.
Mass
48.469 kDa
Sequence
MKQTPDQFSVSHLLSAVESEISAGSEKGDPTERDLKVTLGEKPLWEKFKSLTNEMIVTKSGRRMFPVLKVNVSGLDPNAMYSFLLDFTAADNHRWKYVNGEWVPGGKPEPSVPSCVYIHPDSPNFGAHWMKSPVSFSKVKLTNKLNGGGQQIMLNSLHKYEPRIHIVKVGGPDNQRTLSTHTFAETQFIAVTAYQNEELTALKIKHNPFAKAFLDAKERNDTKSGHDDLTDQQPQFSQLGGWFLPGTGPICPPPNPHQFAPSLGLPSHGCDRYSTLRNHRSAPYPHPYQRSSPPTNYGHDTAASLPMMPTHDNWSGLPVSTHNMLSMSAMPHTTTSTHAQYPNLWSVSNNNLTPTTHAQTHMSGTMGTGLPHQFLRTTAPAPYHSIPTCTVPTTASSSPVYHDSHEVSSTDSGYGHSTTPPAPQTRITSNNWSPMTMPSM
Protein
T-box transcription factor T homolog 2: TBXT

Gene
Tbxt
Protein
T-box transcription factor T
Organism
Mus musculus
Length
436 amino acids
Function
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation (PubMed:7588606). Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site (PubMed:8344258, PubMed:7588606).
Mass
47.44 kDa
Sequence
MSSPGTESAGKSLQYRVDHLLSAVESELQAGSEKGDPTERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVTADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNDHKDVMEEPGDCQQPGYSQWGWLVPGAGTLCPPASSHPQFGGSLSLPSTHGCERYPALRNHRSSPYPSPYAHRNSSPTYADNSSACLSMLQSHDNWSSLGVPGHTSMLPVSHNASPPTGSSQYPSLWSVSNGTITPGSQTAGVSNGLGAQFFRGSPAHYTPLTHTVSAATSSSSGSPMYEGAATVTDISDSQYDTAQSLLIASWTPVSPPSM
Protein
T-box transcription factor T: Tbxt

Gene
TBXT
Protein
T-box transcription factor T
Organism
Canis lupus familiaris
Length
435 amino acids
Function
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site.
Mass
47.148 kDa
Sequence
MSSPGAESAGKSLQYRVDHLLSAVESELQAGSEKGDPTERELRVGLEDSELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGAQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERSDHKDMMEEPGDSQQSGYSQWGWLIPGTSTLCPPATPHPQFGGPLSLPSTHGCERYPALRNHRPSPYPSPYAHRNNSPTYSDNPSACLSMLQSHDSWPSLGTPAHTSMLPMSHSAGPPTGSSQYPSLWSVSNGTITPGAQPAGMSNGLGAQFFRGSSAHGAPLGHAVPAPSASGSPLYEGAPTATDVPDSQYDASAQARLIASWTPVSPPSM
Protein
T-box transcription factor T: TBXT

Gene
TBXT
Protein
T-box transcription factor T
Organism
Homo sapiens
Length
435 amino acids
Function
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site.
Mass
47.443 kDa
Sequence
MSSPGTESAGKSLQYRVDHLLSAVENELQAGSEKGDPTERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERSDHKEMMEEPGDSQQPGYSQWGWLLPGTSTLCPPANPHPQFGGALSLPSTHSCDRYPTLRSHRSSPYPSPYAHRNNSPTYSDNSPACLSMLQSHDNWSSLGMPAHPSMLPVSHNASPPTSSSQYPSLWSVSNGAVTPGSQAAAVSNGLGAQFFRGSPAHYTPLTHPVSAPSSSGSPLYEGAAAATDIVDSQYDAAAQGRLIASWTPVSPPSM
Protein
T-box transcription factor T: TBXT

Gene
TBXT
Protein
T-box transcription factor T homolog
Organism
Hemicentrotus pulcherrimus
Length
434 amino acids
Function
Involved in the transcriptional regulation of genes required for mesoderm differentiation.
Mass
46.714 kDa
Sequence
MPAMSADALRAPSYNVSHLLNAVQSEMNRGSEKGDPSEEGLKVRLDDVELWKKFHKLTNEMIVTKSGRRMFPVLSASIAGLDPNSMYSVLLDFSAADDHRWKYVNGEWIPGGKPDGSPPTTAYIHPDSPNFGAHWMKQAVNFSKVKLSNKLNGSGQVMLNSLHKYEPRIHIIRVGGREKQRLVGSYSFTETRFIAVTAYQNEDITQLKIKYNPFAKAFLDIKDKNDGHDLFDDVHDFQGSKYPQFGGWFLPGSGAFGPTPHQFNPSIGLPSHAGCDRYGGLRSHRTSPYPPPPYHQKYSAAGAGYGAEASAGLSSSISLLAADSWSSLANSTSAASSMPACSQYGSMWPSTAATSGFSHVSSPQSPLPTGLFRNPHPTSSHQHNLASTAHGMAPVASGLPSAAVTTANSSEAHALSQSVMAPGECRASDNAGYL
Protein
T-box transcription factor T homolog: TBXT

Gene
TBXT
Protein
T-box transcription factor T
Organism
Gallus gallus
Length
433 amino acids
Function
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site.
Mass
47.289 kDa
Sequence
MGSPEDAGKAPAYRVDHLLSAVESELQAGSEKGDPTERELRVALEDGELWLRFKELTNEMIVTKNGRRMFPVLKVSVSGLDPNAMYSFLLDFVAADGHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHSFPETQFTAVTAYQNEEITALKIKYNPFAKAFLDAKERNDHKDMMEEAGDNQQSGYSQLGSWLIPGAGALCPPANPHSQFGAPLSLSPAHSCERYSPLRNHRSAPYPNPYTHRNNSPTAYTDNSSACLPMLQSHDNWSSLGVPTHTTMLPMSHSTGTATSSSQYPNLWSVSNSTITPAPQSSGMSNGLSSQFLRGSPVHYTALPHPVTATTSTSPLYDGGAPADLPDSQYDASAHTRLASMWTPITPPSM
Protein
T-box transcription factor T: TBXT

Gene
tbxt
Protein
T-box transcription factor T
Organism
Xenopus laevis
Length
432 amino acids
Function
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Causes dorsal mesodermal differentiation of animal cap ectoderm when co-expressed with wnt8 and noggin. None of these molecules causes dorsal mesoderm formation when expressed alone. Establishes the left/right axis at early gastrula stage by directly up-regulating mesodermal expression of zic3.
Mass
47.599 kDa
Sequence
MSATESCAKNVQYRVDHLLSAVENELQAGSEKGDPTEKELKVSLEERDLWTRFKELTNEMIVTKNGRRMFPVLKVSMSGLDPNAMYTVLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKDPVSFSKVKLTNKMNGGGQIMLNSLHKYEPRIHIVRVGGTQRMITSHSFPETQFIAVTAYQNEEITALKIKHNPFAKAFLDAKERNDYKDILDEGIDSQHSNFSQLGTWLIPNGGSLCSPNPHTQFGAPLSLSSPHGCERYSSLRNHRSAPYPSPYTHRNNSPNNLADNSSACLSMLQSHDNWSTLQMPAHTGMLPMSHSTGTPPPSSQYPSLWSVSNSAITPVSQSGGITNGISSQYLLGSTPHYSSLSHAVPSPSTGSPLYEHGAQTEIAENQYDVTAHSRLSSTWTPVAPPSV
Protein
T-box transcription factor T: tbxt