tbcb

Tubulin-specific chaperone B

270 amino acids

Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer.

Belongs to the TBCB family.

30.454 kDa

MSSTKSDFEIIREYIIGDGKDISVGKAPEGNVRLEITHSVLTGESLGTNNFKNFSLDLKIKDFKEKLYRFVGTEPKYMELILRDENKVNDICKIDDDDDKTLGSYEPKDGMNVHIIDKDPNNFVSELQDISKAPKPVISEEDYNKREGTYKKWKEENQLKKENDTTATTVTATTTTTNNATDTEIEIKVGDRCKVISDDPTNYDERLGKVQYVGTVEFSSGVWIGVELDLPLGKNDGSVKGKQYFQCSPKYGCFAKPKNVLVGDYPEEEI

TBCB

Tubulin-folding cofactor B

244 amino acids

Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.

Belongs to the TBCB family.

27.518 kDa

MEVTGLSAPTVNVFISSSLNSFRSQKRYSRSLTVAEFKCKLQLVVGSPASCMELELYGPDDKFCCKLDQDDALLGSYPVDDGCRIHVIDHSGARLGEYEDISKVEKYEISQEAYEQRQDSIRSFLKRNKLGRFNEEERAQQEAENSQRLIEEEAQASTIPVGSRCEVRTPGQPPRRGTVMYVGLTDFKPGYWIGIRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPSVVTVGDFPEEDYGLDEM

TBCB

Tubulin-folding cofactor B

244 amino acids

Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (PubMed:9265649). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth (By similarity).

Belongs to the TBCB family.

27.326 kDa

MEVTGVSAPTVTVFISSSLNTFRSEKRYSRSLTIAEFKCKLELLVGSPASCMELELYGVDDKFYSKLDQEDALLGSYPVDDGCRIHVIDHSGARLGEYEDVSRVEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPAVVTVGDFPEEDYGLDEI

Tbcb

Tubulin-folding cofactor B

244 amino acids

Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation (PubMed:17184771). May function as a negative regulator of axonal growth (PubMed:17217416).

Belongs to the TBCB family.

27.386 kDa

MEVTGISAPTVMVFISSSLNSFRSEKRYSRSLTIAEFKCKLELVVGSPASCMELELYGADDKFYSKLDQEDALLGSYPVDDGCRIHVIDHSGVRLGEYEDVSKVEKYEISPEAYERRQNTVRSFMKRSKLGPYNEELRAQQEAEAAQRLSEEKAQASAISVGSRCEVRAPDHSLRRGTVMYVGLTDFKPGYWVGVRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPSAVTVGDFPEEDYGLDEM