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TAS2R43

Gene
TAS2R43
Protein
Taste receptor type 2 member 43
Organism
Homo sapiens
Length
309 amino acids
Function
Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity).
Similarity
Belongs to the G-protein coupled receptor T2R family.
Mass
35.599 kDa
Sequence
MITFLPIIFSSLVVVTFVIGNFANGFIALVNSIEWFKRQKISFADQILTALAVSRVGLLWVLLLNWYSTVLNPAFNSVEVRTTAYNIWAVINHFSNWLATTLSIFYLLKIANFSNFIFLHLKRRVKSVILVMLLGPLLFLACHLFVINMNEIVRTKEFEGNMTWKIKLKSAMYFSNMTVTMVANLVPFTLTLLSFMLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVISFLLLCAIYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVFWQMRYWVKGEKTSSP

Gene
TAS2R43
Protein
Taste receptor type 2 member 43
Organism
Pan paniscus
Length
309 amino acids
Function
Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity).
Similarity
Belongs to the G-protein coupled receptor T2R family.
Mass
35.611 kDa
Sequence
MITFLPIIFSSLVVVTFVIGNFANGFIALVNSIEWFKRQKISFADQILTALAVSRVGLLWVLLLNWYLTVLNPAFNSVEVRTTAYNIWAVINHFSNWLATSLSIFYLLKIANFSNFIFLHLKRRVKSVILVMLLGPLLFLACHLFMINMNEIVRTKEFDGNMTWKIKLKSAMYFSNMTVTMVANLVPFTLTLLSFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVISFLLLCAIYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVFWQMRYWVKGEKTSSP

Gene
TAS2R43
Protein
Taste receptor type 2 member 43
Organism
Pan troglodytes
Length
309 amino acids
Function
Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity).
Similarity
Belongs to the G-protein coupled receptor T2R family.
Mass
35.612 kDa
Sequence
MITFLPIIFSSLVVVTFVIGNFANGFIALVNSIEWFKRQKISFADQILTALAVSRVGLLWVLLLNWYSTVLNPAFNSVEVRTTAYNIWAVINHFSNWLATSLSIFYLLKIANFSNFIFLHLKRRVKSVILVMLLGPLLFLACHLFVINMNEIVRTKEFEGNMTWKIKLKSAMYFSNMTVTMVANLVPFTLTLLSFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKVLQTVISFLLLCAIYFLSIMISVWSFGSLKNKPVFMFCKAMRFSYPSIHPFILIWGNKKLKQTFLSVFWQMRYWVKGEKTSSP

Gene
TAS2R43
Protein
Taste receptor type 2 member 43
Organism
Macaca mulatta
Length
308 amino acids
Function
Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity).
Similarity
Belongs to the G-protein coupled receptor T2R family.
Mass
35.353 kDa
Sequence
MITFLPIIFSILVVFTFVIGNFANGFIALVNSIEWVKRQKISFADQILTALAVSRVGLLWILLLNWYSTVLNPAFYSVEVRTIAYNLWAVINHFSNWLATSLSIFYLLKIANFSNLIFLHLRRRVKSVVLVILWGPLLFLVCHLFVVNMNEIIQTKEYEGNMTWKSKLRSAMYLSNTTVTILANLVPFILTLISFLLLICSLCKHLKKMQLRDKGSQDPSTKVHIKALQTVISLSLCAIYFLSIMISSWSLGRVENKAIFMFCKAIRFSYPSAHAFILIWGNKKLKQTLLSVLWNVRYCVKGQKLQSP

Gene
TAS2R43
Protein
Taste receptor type 2 member 43
Organism
Papio hamadryas
Length
308 amino acids
Function
Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity).
Similarity
Belongs to the G-protein coupled receptor T2R family.
Mass
35.168 kDa
Sequence
MITFLPIIFSILVVVTFVIGNCANGFIALVNSTEWVKRQKISFADQILTALAVSRVGLLWVLLLNWYATVLNPAFYSVEVRTIVYNLWAVINHFSNWLATSLSIFYLLKIANFSNLIFLHLKRRVKSVVLVILLGPLLFLVCHLFVVNMNEIVRTKEYEGNMTWKSKLRSAMYLSNTTVTILANLVPFILTLISFLLLICSLCKHLKKMQLRDKGSQDPSTKVHIKALQTVISLLLCVIYFLSIMISSWSLGRVENKAVFMFCKAIRFSYPSAHAFILIWGNKKLKQTLLSVLWNVRYCVKGQKLPSP